MedComm – Biomaterials and Applications,
Год журнала:
2024,
Номер
3(4)
Опубликована: Ноя. 10, 2024
Abstract
The
effective
treatment
of
skin
wounds
has
long
posed
a
significant
challenge
in
the
medical
field,
impacting
patient
comfort,
quality
life,
and
rate
outcome
wound
healing.
With
continuous
advancements
science
technology,
novel
materials
have
emerged,
providing
new
possibilities
for
treatment.
Among
these,
multifunctional
hydrogels
shown
considerable
potential
promoting
healing
as
type
dressing
material.
This
review
systematically
examines
progress
application
Initially,
structure
composition
are
introduced.
Subsequently,
classified,
wound‐healing
process
is
discussed
detail.
Traditional
modern
dressings
then
categorized,
with
particular
emphasis
on
characteristics
applications
hydrogel
dressings.
various
functions
healing,
including
antibacterial,
antioxidant,
hemostatic,
adhesive,
stimulus‐responsive,
status
monitoring,
reviewed.
paper
concludes
summary
existing
research
gaps
provides
insights
into
future
development
directions
hydrogels.
aims
to
guide
preparation
offer
theoretical
references
exploration
next‐generation
functional
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
13(13)
Опубликована: Янв. 31, 2024
Adhesive
hydrogel
holds
huge
potential
in
biomedical
applications,
such
as
hemostasis
and
emergent
wound
management
during
outpatient
treatment
or
surgery.
However,
most
adhesive
hydrogels
underperform
to
offer
robust
adhesions
on
the
wet
tissue,
increasing
risk
of
hemorrhage
reducing
fault
tolerance
To
address
this
issue,
work
develops
a
polysaccharide-based
bioadhesive
tape
(ACAN)
consisting
dual
cross-linking
allyl
cellulose
(AC)
carboxymethyl
chitosan
(CMCS).
The
hygroscopicity
AC
CMCS
networks
enables
ACAN
remove
interfacial
water
from
tissue
surface
initializes
physical
cross-link
instantly.
Subsequently,
covalent
cross-links
are
developed
with
amine
moieties
sustain
long-term
adhesion.
cross-linked
also
has
good
cytocompatibility
controllable
mechanical
properties
matching
where
addition
provides
remarkable
antibacterial
hemostatic
capability.
Moreover,
compared
commercially
available
3
M
film,
an
ultrafast
healing
tissue.
hybrid
have
advantages
biocompatibility
antibacterial,
hemostatic,
properties,
shedding
new
light
first-aid
design
advancing
cellulose-based
materials
technology
for
high-performance
applications.
Advanced Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 19, 2024
Hydrogels
present
attractive
opportunities
as
flexible
sensors
due
to
their
soft
nature
and
tunable
physicochemical
properties.
Despite
significant
advances,
practical
application
of
hydrogel-based
sensor
is
limited
by
the
lack
general
routes
fabricate
materials
with
combination
mechanical,
conductive,
biological
Here,
a
multi-functional
hydrogel
reported
in
situ
polymerizing
acrylamide
(AM)
N,N'-bis(acryloyl)cystamine
(BA)
dynamic
crosslinked
silver-modified
polydopamine
(PDA)
nanoparticles,
namely
PAM/BA-Ag@PDA.
Compared
traditional
polyacrylamide
(PAM)
hydrogel,
BA-Ag@PDA
nanoparticles
provide
both
high-functionality
crosslinks
multiple
interactions
within
PAM
networks,
thereby
endowing
optimized
PAM/BA-Ag@PDA
significantly
enhanced
tensile/compressive
strength
(349.80
kPa
at
383.57%
tensile
strain,
263.08
90%
compressive
strain),
lower
hysteresis
(5.2%),
improved
conductivity
(2.51
S
m
International Journal of Polymeric Materials,
Год журнала:
2024,
Номер
unknown, С. 1 - 25
Опубликована: Окт. 24, 2024
A
Comprehensive
Review
delves
into
the
evolution
of
carboxymethyl
cellulose
(CMC)
modifications
and
their
extensive
utilization
in
biomedical
fields.
Various
cross-linking
agents
methods
such
as
physical,
chemical,
photo,
enzymatic
are
explored
for
enhancing
CMC
properties.
This
modified
exhibits
notable
antimicrobial
antifungal
activities,
rendering
it
pivotal
pharmaceutical
formulations.
Moreover,
its
versatility
extends
to
applications
including
drug
delivery,
tissue
engineering,
wound
dressing,
regenerative
medicine,
bioimaging,
biosensing,
diagnosis,
Vaccine
immunotherapy
other
therapeutic
purposes.
review
provides
a
thorough
insight
multifaceted
roles
contemporary
sciences.
Nano Letters,
Год журнала:
2024,
Номер
24(44), С. 14073 - 14081
Опубликована: Окт. 28, 2024
Moisture-driven
actuators
featuring
programmable
stimuli-responsiveness
and
a
rapid
response
have
garnered
substantial
research
attention.
Cellulose-based
face
challenges,
including
prolonged
unstable
responsiveness,
along
with
inadequate
interfacial
bonding.
Herein,
we
developed
bilayer
structured
moisture
actuator
by
integrating
multiscale
cellulose
fibers
chitosan.
The
protonated
chitosan
forms
strong
electrostatic
attractions
negatively
charged
nanofibrils
(CNF),
achieving
robust
interaction.
Leveraging
the
hierarchically
porous
structure
varying
hygroscopicity
of
microfibrillated
(MFC)
CNF,
film
establishes
an
effective
wettability
gradient,
enabling
stable
actuation
performance.
exhibits
large
deformation
toward
bending
angle
60°,
short
time
12
s,
good
stability
over
50
wetting
drying
cycles,
promising
recyclability.
Harnessing
these
advantageous
properties,
was
demonstrated
for
its
applications
in
automatic
cooling
textiles,
contactless
electrical
switches,
artificial
moisture-activated
muscles,
showing
great
potential
practical
use.
Biomacromolecules,
Год журнала:
2025,
Номер
26(1), С. 689 - 704
Опубликована: Янв. 1, 2025
Chitosan-based
materials
are
known
for
their
excellent
biocompatibility
and
inherent
hemostatic
properties.
However,
efficiency
is
significantly
affected
by
poor
wettability
mechanical
strength.
Herein,
we
developed
a
novel
super
elastic
sponge
from
mussel-inspired
chitosan
modified
with
long
alkyl
catechol
functional
groups
(HMCC)
via
simple
freezing-drying
procedure.
The
incorporation
of
decanal
in
the
HMCC
enhances
its
antimicrobial
antioxidant
properties
facilitates
multiple
interactions
blood
cells,
thus
promoting
enrichment
rapid
hemostasis.
Moreover,
sponges
exhibit
high
compressibility
fluid-induced
size
recovery
capacity,
enabling
wound
shape
adaptation
to
ensure
minimizing
irritation.
In
vivo
experiments
revealed
that
possessed
enhanced
procoagulant,
hemostasis
abilities,
favorable
degradability
could
promote
healing
rat
skin
model.
These
results
highlight
potential
as
promising
solution
clinical
management
major
bleeding.
