Targeted Cancer Therapy‐on‐A‐Chip DOI Creative Commons

Heba Abed,

R. Radha,

Shabana Anjum

и другие.

Advanced Healthcare Materials, Год журнала: 2024, Номер 13(29)

Опубликована: Авг. 5, 2024

Abstract Targeted cancer therapy (TCT) is gaining increased interest because it reduces the risks of adverse side effects by specifically treating tumor cells. TCT testing has traditionally been performed using two‐dimensional (2D) cell culture and animal studies. Organ‐on‐a‐chip (OoC) platforms have developed to recapitulate in vitro, as cancer‐on‐a‐chip (CoC), used for chemotherapeutics development testing. This review explores use CoCs both develop test TCTs, with a focus on three main aspects, identify target biomarkers development, free, un‐encapsulated encapsulated TCTs. Despite current challenges such system scaling, externally triggered TCToC shows promising future serve supportive, pre‐clinical platform expedite bench‐to‐bedside translation.

Язык: Английский

Future prospects of targeted drug delivery DOI
Chandrabose Karthikeyan, Akhilesh Tiwari, Sourajyoti Goswami

и другие.

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 377 - 402

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Targeted Cancer Therapy‐on‐A‐Chip DOI Creative Commons

Heba Abed,

R. Radha,

Shabana Anjum

и другие.

Advanced Healthcare Materials, Год журнала: 2024, Номер 13(29)

Опубликована: Авг. 5, 2024

Abstract Targeted cancer therapy (TCT) is gaining increased interest because it reduces the risks of adverse side effects by specifically treating tumor cells. TCT testing has traditionally been performed using two‐dimensional (2D) cell culture and animal studies. Organ‐on‐a‐chip (OoC) platforms have developed to recapitulate in vitro, as cancer‐on‐a‐chip (CoC), used for chemotherapeutics development testing. This review explores use CoCs both develop test TCTs, with a focus on three main aspects, identify target biomarkers development, free, un‐encapsulated encapsulated TCTs. Despite current challenges such system scaling, externally triggered TCToC shows promising future serve supportive, pre‐clinical platform expedite bench‐to‐bedside translation.

Язык: Английский

Процитировано

1