Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach DOI
M. Akhtar, Hammad Majeed, Tehreema Iftikhar

и другие.

Toxicology Research, Год журнала: 2024, Номер 14(1)

Опубликована: Дек. 31, 2024

Abstract Since the Industrial Revolution, ecological damage, ecosystem disruption, and climate change acceleration have frequently resulted from human advancement at price of environment. Due to rise in illnesses, Industry 6.0 calls for a renewed dedication sustainability with latest technologies. Focused research creative solutions are needed achieve UN Sustainable Development Goals (SDGs), especially 3, 9, 13, 14, 15, 17. A promising sustainable technology enhancing healthcare while reducing environmental effect is Metal Organic Frameworks (MOFs). MOFs perfect drug administration because their high surface areas, adjustable pore sizes, remarkable drug-loading capacities. They created by combining advanced artificial intelligence, intelligent manufacturing, quantum computing. Researchers can create functional groups or ligands that bind selectively target cells tissues, minimizing off-target effects, thanks distinct benefits families like MIL, HKUST, UiO, ZIF etc. offer targeted delivery. Combining other nanomaterials results multipurpose systems handle challenging biomedical issues. Despite its promise, there still issues MOFs’ possible toxicity long-term stability physiological settings. To advance medicinal applications, these problems must be resolved. increase usefulness medicine critically analysing limitations putting up alternatives. The creation technologies (additive manufacturing etc.) delivery prime example how scientific stewardship may coexist provide advantageous both people

Язык: Английский

Two stable metal–organic frameworks with new topology constructed from formic acid-coordinated trinuclear clusters for natural gas purification DOI
Borong Zhang,

Zhaohui Shi,

Xueyue Yu

и другие.

Separation and Purification Technology, Год журнала: 2025, Номер 363, С. 132308 - 132308

Опубликована: Фев. 28, 2025

Язык: Английский

Процитировано

1

ROS-related nanoparticles for the management of Alzheimer’s disease: Wielding the double-edged sword DOI

Yibin Yu,

Qi Zhang, Yihao Guo

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161784 - 161784

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Dual-Functional Amino-MOF with Enhanced Ice Suppression and Intrinsic Photothermal Activity for High-Performance Oocyte Cryopreservation DOI
Pan Wang, Jixiang Zhang,

Minghui Zhan

и другие.

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 28, 2025

The current vitrification-based oocyte cryopreservation relies on inherently cytotoxic high-concentration cryoprotective agents (CPAs), leading to suboptimal post-thaw survival rates and diminished developmental competence. To address this, we developed a series of highly biocompatible amino-functionalized iron-based metal-organic frameworks (Fe-MOFs) via facile hydrothermal method synergistically suppress ice crystallization minimize the reliance toxic CPAs. Among synthesized materials, 2NH2-MIL88(Fe) demonstrated exceptional ice-inhibition performance, reducing crystal size 16.78% that observed in pure water, significantly outperforming its nonaminated counterpart MIL88(Fe) monoaminated NH2-MIL88(Fe). Notably, exhibited an unprecedented intrinsic photothermal response without requiring photosensitizer modification, achieving rapid temperature elevation from 25 86.6 °C under 808 nm laser irradiation (1 W/cm2, 1 min). When applied mouse cryopreservation, this dual-functional amino-MOF enabled complete elimination dimethyl sulfoxide (DMSO) CPAs while maintaining rate 95.1%. Our findings establish dual correlation between amino group density both ice-growth suppression efficiency revealing synergistic mechanism for enhancement. This structure-function relationship provides critical insights rational design next-generation nano-CPAs.

Язык: Английский

Процитировано

0

Nanochannel functionalization using POFs: Progress and prospects DOI
Xuan Kang,

Mingyi Yu,

Yuan Xu

и другие.

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 342, С. 103533 - 103533

Опубликована: Апрель 28, 2025

Язык: Английский

Процитировано

0

Sustainable Green Synthesis, Characterization and Anti-Microbial Testing of Cu-Based Metal-Organic Framework (MOF)/TiO2 Nanocomposites Derived from Cinnamomum Verum Bark DOI

Rohini Sumitra Rajdatta Kadam,

Deepashree D. Kamble,

Aslam Khan

и другие.

Journal for Research in Applied Sciences and Biotechnology, Год журнала: 2025, Номер 4(2), С. 18 - 26

Опубликована: Апрель 12, 2025

This research work is aimed at green synthesis with sustainability towards the production of copper (Cu)-Based Metal Organic Framework (MOF) and their doping in titanium dioxide (TiO₂) nanoparticles synthesized using a natural reductant stabilizer, Cinnamomum verum (C. verum) bark extract. It an eco-friendly technique because bioactive compounds such as flavonoids polyphenols present C. help reduce stabilize metal ions, thus replacing toxic chemicals. The Cu-doped TiO₂ nanocomposites are found to absorb increased visible light owing reduced bandgap from doping, observed by UV-Vis Diffuse Reflectance Spectroscopy (UV-DRS). scanning electron microscopy energy-dispersive X-ray spectroscopy analysis indicates that distribution Cu matrix uniform, which offers structural stability functional efficacy. Well-diffusion experiments on antimicrobial studies reveal produced this process have excellent activity, especially Staphylococcus aureus. attributed photoinduced generation ROS, can break cell walls interfere microbial metabolism. for Cu-TiO2 nanocomposite totally compliance chemistry principles produces having strong photocatalytic action. These results outline grand potential methods-prepared be used coatings, environmental remediation, much more - opening promising route sustainable nanotechnology development.

Язык: Английский

Процитировано

0

Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach DOI
M. Akhtar, Hammad Majeed, Tehreema Iftikhar

и другие.

Toxicology Research, Год журнала: 2024, Номер 14(1)

Опубликована: Дек. 31, 2024

Abstract Since the Industrial Revolution, ecological damage, ecosystem disruption, and climate change acceleration have frequently resulted from human advancement at price of environment. Due to rise in illnesses, Industry 6.0 calls for a renewed dedication sustainability with latest technologies. Focused research creative solutions are needed achieve UN Sustainable Development Goals (SDGs), especially 3, 9, 13, 14, 15, 17. A promising sustainable technology enhancing healthcare while reducing environmental effect is Metal Organic Frameworks (MOFs). MOFs perfect drug administration because their high surface areas, adjustable pore sizes, remarkable drug-loading capacities. They created by combining advanced artificial intelligence, intelligent manufacturing, quantum computing. Researchers can create functional groups or ligands that bind selectively target cells tissues, minimizing off-target effects, thanks distinct benefits families like MIL, HKUST, UiO, ZIF etc. offer targeted delivery. Combining other nanomaterials results multipurpose systems handle challenging biomedical issues. Despite its promise, there still issues MOFs’ possible toxicity long-term stability physiological settings. To advance medicinal applications, these problems must be resolved. increase usefulness medicine critically analysing limitations putting up alternatives. The creation technologies (additive manufacturing etc.) delivery prime example how scientific stewardship may coexist provide advantageous both people

Язык: Английский

Процитировано

2