Employing Copper-Based Nanomaterials to Combat Multi-Drug-Resistant Bacteria

Microorganisms, Год журнала: 2025, Номер 13(4), С. 708 - 708

Опубликована: Март 21, 2025

The rise of multi-drug-resistant (MDR) bacteria poses a severe global threat to public health, necessitating the development innovative therapeutic strategies overcome these challenges. Copper-based nanomaterials have emerged as promising agents due their intrinsic antibacterial properties, cost-effectiveness, and adaptability for multifunctional approaches. These materials exhibit exceptional potential in advanced therapies, including chemodynamic therapy (CDT), photothermal (PTT), photodynamic (PDT). Their unique physicochemical such controlled ion release, reactive oxygen species (ROS) generation, tunable catalytic activity, enable them target MDR effectively while minimizing off-target effects. This paper systematically reviews mechanisms through which Cu-based enhance efficiency emphasizes specific performance field. Key factors influencing properties—such electronic interactions, characteristics, size effects, ligand single-atom doping, geometric configurations—are analyzed depth. By uncovering copper-based nanomaterials, this work aims inspire approaches that improve patient outcomes, reduce burden bacterial infections, health initiatives.

Язык: Английский

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Construction of pH-Responsive Copper Sulfide Nanocomposites and Their Photothermal/Chemodynamic Synergistic Antibacterial Studies

ACS Applied Nano Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 15, 2025

Язык: Английский

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Potential‐Driven Dynamic Spring‐Effect of Pd─Cu Dual‐Atoms Empowered Stability and Activity for Electrocatalytic Reduction

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Апрель 26, 2025

Abstract Atomic‐level catalysts are extensively applied in heterogeneous catalysis fields. However, it is a general but ineluctable issue that active metal atoms may migrate, aggregate, deactivate, or leach during reaction processes, suppressing their catalytic performances. Designing superior intrinsic‐structural stability of atomic‐level with high activity and revealing dynamic structure evolution vital for wide applications complex reactions harsh conditions. Herein, high‐stable Pd─Cu dual‐atom PdN 3 ─CuN coordination engineered via strong chelation Cu 2+ ‐ions electron pairs from palladium‐source, achieving the highest turnover frequency under lowest overpotential Cr(VI) electrocatalytic reduction detection strong‐acid electrolytes. In situ X‐ray absorption fine spectra reveal “spring‐effect” Cu─Pd Cu─N bonds reversibly stretched potential changes can be recovered at 0.6 V regeneration. The modulated electron‐orbit coupling effect prevents Cu‐atoms aggregating as metallic nanoparticles. dual‐atoms interact two O H 2 CrO 4 , forming stable bridge configurations transferring electrons to promote Cr─O bond dissociation, which prominently decreases energy barriers. This work provides feasible route boost robustness single‐atoms easily affected by conditions sustainable applications.

Язык: Английский

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Nanoconfinement-guided in situ co-deposition of single-atom cascade nanozymes combined with injectable sodium alginate hydrogels for enhanced diabetic wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140814 - 140814

Опубликована: Фев. 1, 2025

Язык: Английский

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Engineering oxygen vacancies in scaffold for enhanced photodynamic antibacterial efficacy

Vacuum, Год журнала: 2025, Номер unknown, С. 114151 - 114151

Опубликована: Март 1, 2025

Язык: Английский

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Development of an aminoguanidine hybrid hydrogel composites with hydrogen and oxygen supplying performance to boost infected diabetic wound healing

Journal of Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 137401 - 137401

Опубликована: Март 1, 2025

Язык: Английский

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