bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Март 11, 2025
The
exponential
growth
of
scientific
publications
presents
opportunities
for
researchers
to
identify
valuable
knowledge,
especially
in
the
highly
interdisciplinary
field
---
biomaterials,
where
exploiting
possible
connections
between
unmet
clinical
needs
and
materials
properties
from
literatures
is
crucial.
However,
with
traditional
literature
reading,
it
extremely
challenging
marry
existing
reported
different
applications
or
other
purposes.
Here,
provide
a
not-renally
cleared
therapeutics
renally
impaired
hyperuricemia
patients,
we
designed
multi-tiered
framework
MatWISE
that
fuses
state-of-the-art
natural
language
processing,
semantic
relationship
mapping,
machine
learning
automate
complex
process
material
discovery
sea
published
until
December
2022,
successfully
identified
optimized
δ-MnO
2
into
an
orally
administered,
nonabsorbable
uric
acid
(UA)
lowering
biomaterial.
had
superior
serum
urine
UA-lowering
effect
three
mouse
models,
by
comparing
standard
care
drug.
promising
serve
as
safe
effective
drug
patients.
We
demonstrated
new
research
paradigm
biomaterials
combining
techniques
handful
experiments
discover
translationally
relevant
massive
research,
need.
Copper
(Cu)
is
currently
the
dominant
interconnect
material
in
back-end-of-line
processes
due
to
its
low
bulk
resistivity
(ρ0).
Unfortunately,
increases
significantly
at
small
dimensions
a
long
electron
mean
free
path
(EMFP,
λ)
of
39
nm,
which
leads
enhanced
scattering
grain
boundaries
and
surfaces,
thereby
limiting
high-density
integration.
In
this
study,
we
demonstrate
that
single-phase
hexagonal-close-packed
(HCP)
nickel–cobalt
(NiCo)
alloy
thin
films
exhibit
reduced
size
effect,
outperforming
Cu
for
thicknesses
below
8
nm
(19.83
μΩ·cm
4.9
nm).
First-principles
calculations
predicted
lower
ρ0·λ
5.68
×
10–16
Ω
m2
HCP
NiCo
(xx)
than
(6.73
m2),
significant
contribution
from
short
EMFP
approximately
5
alloy.
To
date,
growth
film
had
not
been
achieved,
as
both
face-centered-cubic
(FCC)
phases
coexist
Co
concentration
50–80
atom
%.
However,
were
successfully
grown
by
using
an
seed
layer,
lattice
mismatch
with
sapphire
(0001)
substrate.
Moreover,
can
be
dry
etched,
providing
advantage
device
fabrication,
since
it
does
require
damascene
process
unlike
Cu.
The
also
exhibited
high
thermal
stability
above
500
°C.
Therefore,
considered
promising
alternative
overcome
scaling
limitations
interconnects.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
The
traditional
trial-and-error
approach,
although
effective,
is
inefficient
for
optimizing
rubber
composites.
latest
developments
in
machine
learning
(ML)-assisted
methodologies
are
also
not
suitable
predicting
and
composite
properties.
This
due
to
the
dependency
of
properties
on
processing
conditions,
which
prevents
alignment
data
collected
from
different
sources.
In
this
work,
a
novel
workflow
called
ML-enhanced
approach
proposed.
integrates
orthogonal
experimental
design
with
symbolic
regression
(SR)
effectively
extract
empirical
principles.
combination
enables
optimization
process
retain
characteristics
while
significantly
improving
efficiency
capability.
Using
composites
as
model
system,
extracts
principles
encapsulated
by
high-frequency
terms
SR-derived
mathematical
formulas,
offering
clear
guidance
material
property
optimization.
An
online
platform
has
been
developed
that
allows
no-code
usage
proposed
methodology,
designed
seamlessly
integrate
into
existing
process.
Advanced Energy Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 24, 2025
Abstract
Post‐Li
battery
technologies
are
becoming
increasingly
important.
The
diverse
range
of
electrically
powered
devices
requires
a
diversification
electrochemical
energy
storage
technologies.
Organic
electrode
materials
particular
importance
for
alternative
batteries,
not
only
because
the
natural
abundance
their
constituting
elements
and
low
toxicity,
but
also
operating
principle
redox
reactions
compatibility
with
many
types
chemistries,
including
multivalent
metal
anionic
batteries.
All‐organic
batteries
still
“young”
field
research
offer
promising
opportunities
in
terms
mechanical
processing
properties.
In
development
using
organic
understanding
mechanisms,
different
cell
correct
interpretation
data
is
utmost
importance.
This
comprehensive
review
offers
insight
into
working
organic‐based
material
design
considerations,
structure‐property
relations,
highlighting
standardized
terminology,
characterization
newly
developed
cells,
distinguishing
between
half‐cells
full‐cells.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Март 11, 2025
The
exponential
growth
of
scientific
publications
presents
opportunities
for
researchers
to
identify
valuable
knowledge,
especially
in
the
highly
interdisciplinary
field
---
biomaterials,
where
exploiting
possible
connections
between
unmet
clinical
needs
and
materials
properties
from
literatures
is
crucial.
However,
with
traditional
literature
reading,
it
extremely
challenging
marry
existing
reported
different
applications
or
other
purposes.
Here,
provide
a
not-renally
cleared
therapeutics
renally
impaired
hyperuricemia
patients,
we
designed
multi-tiered
framework
MatWISE
that
fuses
state-of-the-art
natural
language
processing,
semantic
relationship
mapping,
machine
learning
automate
complex
process
material
discovery
sea
published
until
December
2022,
successfully
identified
optimized
δ-MnO
2
into
an
orally
administered,
nonabsorbable
uric
acid
(UA)
lowering
biomaterial.
had
superior
serum
urine
UA-lowering
effect
three
mouse
models,
by
comparing
standard
care
drug.
promising
serve
as
safe
effective
drug
patients.
We
demonstrated
new
research
paradigm
biomaterials
combining
techniques
handful
experiments
discover
translationally
relevant
massive
research,
need.
