Integrating 3D Bioprinting and Organoids to Better Recapitulate the Complexity of Cellular Microenvironments for Tissue Engineering

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Дек. 8, 2024

Abstract Organoids, with their capacity to mimic the structures and functions of human organs, have gained significant attention for simulating pathophysiology been extensively investigated in recent past. Additionally, 3D bioprinting, as an emerging bio‐additive manufacturing technology, offers potential constructing heterogeneous cellular microenvironments, thereby promoting advancements organoid research. In this review, latest developments bioprinting technologies aimed at enhancing engineering are introduced. The commonly used methods materials organoids, a particular emphasis on advantages combining organoids summarized. These include achieving high cell concentrations form large aggregates, precise deposition building blocks create complex functions, automation throughput ensure reproducibility standardization culture. Furthermore, review provides overview relevant studies from years discusses current limitations prospects future development.

Язык: Английский

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Light-Based 3D Bioprinting Techniques for Illuminating the Advances of Vascular Tissue Engineering

Materials Today Bio, Год журнала: 2024, Номер 29, С. 101286 - 101286

Опубликована: Окт. 2, 2024

Vascular tissue engineering faces significant challenges in creating

Язык: Английский

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The Assembly of Miniaturized Droplets toward Functional Architectures

Small, Год журнала: 2024, Номер 20(46)

Опубликована: Окт. 9, 2024

Abstract Recent explorations of bioengineering have generated new concepts and strategies for the processing soft functional materials. Droplet assembly techniques can address problems in construction extremely architectures by expanding manufacturing capabilities using droplets containing liquid or hydrogels including weak hydrogels. This Perspective sets out to provide a brief overview this growing field, discusses challenges opportunities ahead. The study highlights recent key advances materials from hitherto effective droplet‐assembly technologies, as well applications biomedical fields artificial tissues bioreactors. It is envisaged that these assembled architectures, nature‐inspired models, will stimulate discovery biomaterials miniaturized platforms interdisciplinary research health, biotechnology, sustainability.

Язык: Английский

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Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks

Biomaterials Science, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

This study reports a photoinitiator- and radical-free biocompatible crosslinking method based on ortho-nitrobenzyl alcohol, which provides versatile approach to generate dynamic hydrogels crosslink pristine proteins for biomedical applications.

Язык: Английский

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Bioprinting Approaches in Cardiac Tissue Engineering to Reproduce Blood-Pumping Heart Function

iScience, Год журнала: 2024, Номер 28(1), С. 111664 - 111664

Опубликована: Дек. 20, 2024

Язык: Английский

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