Piezoelectric nanofilms fabricated by coaxial electrospun polycaprolactone/Barium titanate promote Achilles tendon regeneration by reducing IL-17A/NF-κB-mediated inflammation

Bioactive Materials, Год журнала: 2025, Номер 49, С. 1 - 22

Опубликована: Март 1, 2025

Язык: Английский

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Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 17, 2025

Abstract Nerve guidance conduits capable of wireless stimulation represent a promising approach for addressing peripheral nerve defects. However, traditional electrical methods are not sufficiently convenient and may cause secondary damage. In this study, conductive conduit combined with using alternating magnetic fields is presented. The coated nanographene incorporated Fe 3 O 4 nanoparticles induces currents creates supportive microenvironment enhancing regeneration. Finite element analysis confirms that the generates electromotive force under an external field. exhibits improved morphology, physicochemical properties, conductivity by six orders magnitude. vitro experiments demonstrate promotes Schwann cell proliferation, migration, intercellular communication through microcurrents, as well neuronal axon extension. TEM images confirm extension myelin sheath thickness, indicating its high efficiency in promoting regeneration across vivo studies show generated microcurrent electromagnetic stimulation, significantly restoration, gastrocnemius muscle regeneration, motor function recovery, tissue growth, achieving results comparable to gold‐standard autograft method. Overall, work highlights effectiveness induction repair presents new, non‐invasive

Язык: Английский

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Ultrasound-driven piezoelectric hydrogel enhances Schwann/neural stem cell Co-transplantation for spinal cord injury repair

Materials & Design, Год журнала: 2025, Номер unknown, С. 113842 - 113842

Опубликована: Март 1, 2025

Язык: Английский

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The therapeutic application of hydrogels in chronic pain

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106829 - 106829

Опубликована: Март 1, 2025

Язык: Английский

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Reprogrammable shape morphing hydrogel modulated by synergistic photochromism and photoactuation

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162103 - 162103

Опубликована: Март 1, 2025

Язык: Английский

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