Precision Pore Structure Optimization of Additive Manufacturing Porous Tantalum Scaffolds for Bone Regeneration : A proof-of-concept study

Biomaterials, Год журнала: 2024, Номер 313, С. 122756 - 122756

Опубликована: Авг. 15, 2024

Язык: Английский

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Probiotic biofilm modified scaffolds for facilitating osteomyelitis treatment through sustained release of bacteriophage and regulated macrophage polarization

Materials Today Bio, Год журнала: 2025, Номер 30, С. 101444 - 101444

Опубликована: Янв. 7, 2025

Язык: Английский

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New insights into constitutive neutrophil death

Cell Death Discovery, Год журнала: 2025, Номер 11(1)

Опубликована: Янв. 12, 2025

Neutrophils undergo rapid aging and death known as constitutive or spontaneous death. Constitutive neutrophil (CND) contributes to homeostasis inflammation resolution. CND has long been considered be apoptotic until our findings reveal that it was a heterogeneous combination of diverse Furthermore, dead neutrophils retain functional roles via multiple manners. This review provides an overview current research on the mechanism modulation CND. More noteworthy, we also summarize after-death events neutrophils. The fate can changed under pathological conditions, so involvement in diseases CND-related therapeutic strategies are addressed.

Язык: Английский

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Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection

Biomaterials, Год журнала: 2024, Номер 313, С. 122772 - 122772

Опубликована: Авг. 24, 2024

Язык: Английский

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Novel Palladium Hydride Surface Enabling Simultaneous Bacterial Killing and Osteogenic Formation through Proton Capturing and Activation of Antioxidant System in Immune Microenvironments

Advanced Materials, Год журнала: 2024, Номер 36(31)

Опубликована: Май 17, 2024

Achieving bacterial killing and osteogenic formation on an implant surface rarely occurs. In this study, a novel design-a palladium hydride (PdH

Язык: Английский

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Development of endolysin-integrated pH-responsive antiadhesive and antibacterial coatings with nanorods for the prevention of cross-contamination in fresh produce

Food Research International, Год журнала: 2025, Номер 202, С. 115762 - 115762

Опубликована: Янв. 19, 2025

Язык: Английский

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A microenvironment responsive polyetheretherketone implant with antibacterial and osteoimmunomodulatory properties facilitates osseointegration

Bioactive Materials, Год журнала: 2024, Номер 43, С. 273 - 291

Опубликована: Сен. 25, 2024

Язык: Английский

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Engineering Surface-Adaptive Metal–Organic Framework Armor to Promote Infected Wound Healing

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 17(1), С. 776 - 789

Опубликована: Дек. 17, 2024

Metal–organic frameworks (MOFs) hold enormous promise for treating bacterial infections to circumvent the threat of antibiotic resistance. However, positioning MOFs on wound dressings is hindered and remains a significant challenge. Herein, facile heterointerfacial engineering strategy was developed tailor "MOF armor" that adaptively weaponized poly(ε-caprolactone) electrospun dressing with excellent bacteria-killing efficacy. Hydrophilic epitaxial crystallization enhance interfacial wettability key induce uniform seeding Cu2+ thus generate compact MOF layer dressing. The universality proposed demonstrated by construction different kinds (HKUST-1, ZIF-8, ZIF-67) variously shaped substrates (nanofibers, pellets, plates, 3D-printed porous scaffolds). By optimizing loading, Cu-MOF armor exhibited sustained ion release behavior, strong antibacterial activity, good biocompatibility. In vivo rat model revealed significantly promoted infected healing inhibiting inflammatory factors, promoting collagen deposition, angiogenesis. This unique provides an appealing effective solution designing fabricating advanced dressings.

Язык: Английский

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Rational regulation of post-electrodialysis electrochromic anion exchange membranes via TiO2@Ag synergistically strengthens visible-light photocatalytic anti-contamination activity

Water Research, Год журнала: 2024, Номер 263, С. 122178 - 122178

Опубликована: Авг. 2, 2024

Язык: Английский

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Multifunctionally disordered TiO₂ nanoneedles prevent periprosthetic infection and enhance osteointegration by killing bacteria and modulating the osteoimmune microenvironment

Theranostics, Год журнала: 2024, Номер 14(15), С. 6016 - 6035

Опубликована: Янв. 1, 2024

Total hip arthroplasty (THA) and total knee (TKA) are effective interventions for end-stage osteoarthritis; however, periprosthetic infection is a devastating complication of arthroplasty. To safely prevent enhance osteointegration, the surface modification strategy was utilized to kill bacteria, modulate osteoimmune microenvironment, improve new bone formation.

Язык: Английский

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