
Fundamental Research, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 1, 2024
Язык: Английский
Fundamental Research, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 1, 2024
Язык: Английский
Antioxidants, Год журнала: 2024, Номер 13(10), С. 1174 - 1174
Опубликована: Сен. 26, 2024
Cadmium (Cd
Язык: Английский
Процитировано
10Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159956 - 159956
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)
Опубликована: Янв. 29, 2025
Overproduction of reactive oxygen species (ROS), elevated synovial inflammation, hyperplasia and fibrosis are the main characteristic microenvironment in rheumatoid arthritis (RA). Macrophages fibroblast-like synoviocytes (FLSs) play crucial roles progression RA. Hence, synergistic combination ROS scavenging, macrophage polarization from pro-inflammatory M1 phenotype towards M2 anti-inflammatory phenotype, restoring homeostasis FLSs will provide a promising therapeutic strategy for In this study, we successfully synthesized metformin-derived carbon dots (MCDs), investigated antirheumatic effect vivo vitro. Designed MCDs could target inflamed cells accumulate at inflammatory joints collagen-induced (CIA) rats. investigation suggested that reduced inflammation hyperplasia, ultimately prevented cartilage destruction, bone erosion, CIA addition, eliminated cellular macrophages RA through enzyme-like catalytic activity as well inhibiting NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome signaling pathway, effectively polarizing them into to realize effect. Furthermore, inhibit proliferation, migration, FLSs. Mechanistically, restored while reducing level by blocking IL-6/gp130 pathway. Combined with preferable biocompatibility, offer prospective treatment approach
Язык: Английский
Процитировано
0Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Фев. 12, 2025
The continuous destruction of the global ecological environment has led to increased natural disasters and adverse weather, severely affecting crop yields quality, particularly due abiotic stress. Nanase, a novel artificial enzyme, simulates various enzyme activities, is renewable, shows significant potential in promoting growth mitigating This study reviews classification nanoenzymes into carbon-based, metal-based, metal oxide-based, others based on synthesis materials. catalytic mechanisms these are discussed, encompassing such as oxidases, peroxidases, catalases, superoxide dismutases. alleviating salt, drought, high-temperature, low-temperature, heavy metal, other stresses crops also highlighted. Furthermore, challenges faced by especially sustainable agricultural development. review provides insights applying agriculture offers theoretical guidance for stress crops.
Язык: Английский
Процитировано
0Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160576 - 160576
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0The Crop Journal, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Plant Physiology and Biochemistry, Год журнала: 2025, Номер 222, С. 109777 - 109777
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
0Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер 72(42), С. 23008 - 23023
Опубликована: Окт. 14, 2024
The demand for food has increased dramatically as the global population increases, putting more strain on sustainability of agriculture. To fulfill this requirement, it is imperative to develop brand-new technologies. application potential nanozymes in plant and environmental sectors progressively becoming apparent a result their effective enzymatic catalytic activity distinctive characteristics nanomaterials, including size, specific surface area, optical properties, thermal properties. Herein, we systematically analyze mechanisms with different enzyme-mimetic activities summarize applications improving crop yields by regulating ROS levels enhancing stress resistance detecting removing hazardous pollutants. Finally, thoroughly challenges faced regarding design, application, economy, biosafety look forward future development directions better serve sustainable
Язык: Английский
Процитировано
2Fundamental Research, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
2