Nanomaterials in cancer immunotherapy: targeting cancer-associated fibroblasts
Cancer Nanotechnology,
Год журнала:
2025,
Номер
16(1)
Опубликована: Янв. 17, 2025
Emphasizing
the
significance
of
cancer-associated
fibroblasts
(CAFs),
non-malignant
yet
pivotal
players
within
tumor
microenvironment
(TME),
this
review
illuminates
role
inflammatory
subtype
(iCAF)
as
catalysts
in
cancer
proliferation,
metastasis,
and
therapeutic
resistance.
Given
their
paramount
importance,
targeting
CAFs
emerges
a
robust
strategy
evolving
landscape
immunotherapy.
Nanomaterials,
distinguished
by
unique
features
malleability,
hold
considerable
promise
biomedicine,
especially
precision-oriented
domain
therapy.
Their
aptitude
for
modulating
immune
responses,
amplifying
drug
efficacy
through
precise
delivery,
discerningly
focusing
on
cells
TME
situates
nanomaterials
formidable
tools
to
transcend
boundaries
set
conventional
treatments.
This
scrutinizes
convoluted
interplay
among
CAFs,
cells,
TME.
It
further
showcases
widely
utilized
management.
We
underscore
potential
nanoscale
delivery
systems
directed
at
underscoring
transformative
power
revolutionizing
therapies,
enhancing
precision,
culminating
improved
patient
outcomes.
Язык: Английский
Nanomaterials in the diagnosis and treatment of gastrointestinal tumors: New clinical choices and treatment strategies
Materials Today Bio,
Год журнала:
2025,
Номер
32, С. 101782 - 101782
Опубликована: Апрель 19, 2025
Язык: Английский
Amino acid-like “Edge” and nanozyme “Core” structured CDs for overcoming cellular uptake barrier and enhancing tumor penetration
Luming Song,
Ye He,
Liu Zhu
и другие.
Chemical Engineering Journal,
Год журнала:
2025,
Номер
512, С. 162712 - 162712
Опубликована: Апрель 16, 2025
Язык: Английский
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 16, 2025
Abstract
The
rapidly
advancing
field
of
theranostics
aims
to
integrate
therapeutic
and
diagnostic
functionalities
into
a
single
platform
for
precision
medicine,
enabling
the
simultaneous
treatment
monitoring
diseases.
Photo‐energy
conversion‐based
nanomaterials
have
emerged
as
versatile
that
utilizes
unique
properties
light
activate
with
high
spatial
temporal
precision.
This
review
provides
comprehensive
overview
recent
developments
in
photo‐energy
conversion
using
nanomaterials,
highlighting
their
applications
disease
theranostics.
discussion
begins
by
exploring
fundamental
principles
including
types
materials
used
various
light‐triggered
mechanisms,
such
photoluminescence,
photothermal,
photoelectric,
photoacoustic,
photo‐triggered
SERS,
photodynamic
processes.
Following
this,
delves
broad
spectrum
emphasizing
role
diagnosis
major
diseases,
cancer,
neurodegenerative
disorders,
retinal
degeneration,
osteoarthritis.
Finally,
challenges
opportunities
technologies
are
discussed,
aiming
advance
personalized
medicine.
Язык: Английский
Golden insights for exploring cancer: delivery, from genes to the human body using bimetallic Au/Ag nanostructures
Discover Oncology,
Год журнала:
2025,
Номер
16(1)
Опубликована: Май 25, 2025
Sweeping
contact
with
cancer
continues
to
rise
globally,
which
has
led
advanced
research
on
new
treatment
approaches;
nanotechnology
become
crucial
targeted
therapy.
Within
the
intimate
of
nanomaterials,
Au/Ag
nanostructures
have
emerged
as
highly
attractive
because
their
distinctive
desirable
characteristics
and
prospective
roles
in
diagnosis
well
The
developed
revealed
remarkable
biocompatibility,
optically
recursive
alteration,
magnificently
improved
therapeutic
effects
gold
silver
conjunction
each
other.
This
review
addresses
molecular
systemic
aspects
research,
including
impact
genetic
pathways
use
administration
human
organism.
We
explain
some
related
mechanisms
action,
such
photothermal
therapy
(PTT),
photodynamic
(PDT),
drug
delivery
systems
where
they
display
potential
benefits
towards
offering
a
more
approach
fewer
side
effects.
latest
development
shown
that
prospect
real-time
imaging
biomarker
identification,
owing
this
are
being
viewed
tool
for
individualized
treatment.
However,
there
still
limitations:
challenges
scaling
up,
biological
safety,
bringing
it
clinic.
It
is
therefore
incumbent
upon
these
managements
overcome
hurdles
optimize
impact.
As
result,
current
findings
briefly
reviewed,
directions
discussed
support
revolutionary
role
Язык: Английский