Golden insights for exploring cancer: delivery, from genes to the human body using bimetallic Au/Ag nanostructures DOI Creative Commons
Misbah Ullah Khan, Humaira Aslam, Muhammad Jehanzeb Sohail

и другие.

Discover Oncology, Год журнала: 2025, Номер 16(1)

Опубликована: Май 25, 2025

Sweeping contact with cancer continues to rise globally, which has led advanced research on new treatment approaches; nanotechnology become crucial targeted therapy. Within the intimate of nanomaterials, Au/Ag nanostructures have emerged as highly attractive because their distinctive desirable characteristics and prospective roles in diagnosis well The developed revealed remarkable biocompatibility, optically recursive alteration, magnificently improved therapeutic effects gold silver conjunction each other. This review addresses molecular systemic aspects research, including impact genetic pathways use administration human organism. We explain some related mechanisms action, such photothermal therapy (PTT), photodynamic (PDT), drug delivery systems where they display potential benefits towards offering a more approach fewer side effects. latest development shown that prospect real-time imaging biomarker identification, owing this are being viewed tool for individualized treatment. However, there still limitations: challenges scaling up, biological safety, bringing it clinic. It is therefore incumbent upon these managements overcome hurdles optimize impact. As result, current findings briefly reviewed, directions discussed support revolutionary role

Язык: Английский

Nanomaterials in cancer immunotherapy: targeting cancer-associated fibroblasts DOI Creative Commons

Zhongsong Zhang,

Long Chen

Cancer Nanotechnology, Год журнала: 2025, Номер 16(1)

Опубликована: Янв. 17, 2025

Emphasizing the significance of cancer-associated fibroblasts (CAFs), non-malignant yet pivotal players within tumor microenvironment (TME), this review illuminates role inflammatory subtype (iCAF) as catalysts in cancer proliferation, metastasis, and therapeutic resistance. Given their paramount importance, targeting CAFs emerges a robust strategy evolving landscape immunotherapy. Nanomaterials, distinguished by unique features malleability, hold considerable promise biomedicine, especially precision-oriented domain therapy. Their aptitude for modulating immune responses, amplifying drug efficacy through precise delivery, discerningly focusing on cells TME situates nanomaterials formidable tools to transcend boundaries set conventional treatments. This scrutinizes convoluted interplay among CAFs, cells, TME. It further showcases widely utilized management. We underscore potential nanoscale delivery systems directed at underscoring transformative power revolutionizing therapies, enhancing precision, culminating improved patient outcomes.

Язык: Английский

Процитировано

2

Nanomaterials in the diagnosis and treatment of gastrointestinal tumors: New clinical choices and treatment strategies DOI Creative Commons
Liping Chen,

Qingqing Li

Materials Today Bio, Год журнала: 2025, Номер 32, С. 101782 - 101782

Опубликована: Апрель 19, 2025

Язык: Английский

Процитировано

1

Amino acid-like “Edge” and nanozyme “Core” structured CDs for overcoming cellular uptake barrier and enhancing tumor penetration DOI

Luming Song,

Ye He,

Liu Zhu

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер 512, С. 162712 - 162712

Опубликована: Апрель 16, 2025

Язык: Английский

Процитировано

0

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics DOI Creative Commons
Jingyu Shi, Yadi Fan, Qin Zhang

и другие.

Advanced Materials, Год журнала: 2025, Номер unknown

Опубликована: Май 16, 2025

Abstract The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment monitoring diseases. Photo‐energy conversion‐based nanomaterials have emerged as versatile that utilizes unique properties light activate with high spatial temporal precision. This review provides comprehensive overview recent developments in photo‐energy conversion using nanomaterials, highlighting their applications disease theranostics. discussion begins by exploring fundamental principles including types materials used various light‐triggered mechanisms, such photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered SERS, photodynamic processes. Following this, delves broad spectrum emphasizing role diagnosis major diseases, cancer, neurodegenerative disorders, retinal degeneration, osteoarthritis. Finally, challenges opportunities technologies are discussed, aiming advance personalized medicine.

Язык: Английский

Процитировано

0

Golden insights for exploring cancer: delivery, from genes to the human body using bimetallic Au/Ag nanostructures DOI Creative Commons
Misbah Ullah Khan, Humaira Aslam, Muhammad Jehanzeb Sohail

и другие.

Discover Oncology, Год журнала: 2025, Номер 16(1)

Опубликована: Май 25, 2025

Sweeping contact with cancer continues to rise globally, which has led advanced research on new treatment approaches; nanotechnology become crucial targeted therapy. Within the intimate of nanomaterials, Au/Ag nanostructures have emerged as highly attractive because their distinctive desirable characteristics and prospective roles in diagnosis well The developed revealed remarkable biocompatibility, optically recursive alteration, magnificently improved therapeutic effects gold silver conjunction each other. This review addresses molecular systemic aspects research, including impact genetic pathways use administration human organism. We explain some related mechanisms action, such photothermal therapy (PTT), photodynamic (PDT), drug delivery systems where they display potential benefits towards offering a more approach fewer side effects. latest development shown that prospect real-time imaging biomarker identification, owing this are being viewed tool for individualized treatment. However, there still limitations: challenges scaling up, biological safety, bringing it clinic. It is therefore incumbent upon these managements overcome hurdles optimize impact. As result, current findings briefly reviewed, directions discussed support revolutionary role

Язык: Английский

Процитировано

0