Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential DOI Open Access

Peng Zhang,

Qing Zhou, Rujie He

и другие.

Materials, Год журнала: 2024, Номер 17(24), С. 6092 - 6092

Опубликована: Дек. 13, 2024

Bionic bioceramic scaffolds are essential for achieving excellent implant properties and biocompatible behavior. In this study, inspired by the microstructure of natural bone, bionic hydroxyapatite (HAp) ceramic with different structures (body-centered cubic (BCC), face-centered (FCC), gyroid Triply Periodic Minimal Surfaces (TPMSs)) porosities (80 vol.%, 60 40 vol.%) were designed, 3D-printed, characterized. The effects structure porosity on morphology, mechanical properties, in vitro biocompatibility HAp studied compared each other. Interestingly, scaffold a 80 vol.% TPMS had best combination compressive strength biocompatibility, demonstrated great biomedical application potential bone repair. We hope study can provide reference development field repair engineering.

Язык: Английский

Cellulose nanocrystal composite films for contactless moisture-electric conversion DOI Creative Commons

Wenna Ge,

Quanmao Wei,

Xu Wang

и другие.

RSC Advances, Год журнала: 2025, Номер 15(4), С. 2651 - 2656

Опубликована: Янв. 1, 2025

A cellulose nanocrystal composite film-based soft moisture-electric converter demonstrates high sensitivity to ambient humidity fluctuations, allowing contactless control without requiring an external power source.

Язык: Английский

Процитировано

0

First-Principles Study of Mechanical Properties of Pb(ZrxTi1−x)O3 in the Cubic and Tetragonal Phase DOI Creative Commons

Xudong Ran,

Shaolan Zhou,

Shaowen Zhou

и другие.

Crystals, Год журнала: 2025, Номер 15(2), С. 160 - 160

Опубликована: Фев. 5, 2025

In this study, we employed the first-principles method based on density functional theory to calculate elastic constants, bulk modulus, shear Young’s Poisson’s ratio, and of states for both cubic tetragonal phases Pb(ZrxTi1−x)O3. The structural model Pb(ZrxTi1−x)O3 was established using virtual crystal approximation (VCA). Our results demonstrate that VCA-calculated properties are in excellent agreement with other theoretical predictions experimental data. As Zr content increases, lattice constants increase, while c/a ratio initially decreases subsequently increases. Both satisfy Born stability criteria, indicating mechanical stability. For phase, modulus decrease increasing content. contrast, moduli exhibit a non-monotonic trend, peaking at 0.5, where Pb(Zr0.5Ti0.5)O3 demonstrates superior properties. A comparative analysis reveals as phase exhibits enhanced resilience, greater electronic structure stability, increased anisotropy. These characteristics make more suitable advanced manufacturing techniques such additive manufacturing, offering design flexibility ferroelectric materials.

Язык: Английский

Процитировано

0

Piezoelectricity Promotes 3D-Printed BTO/β-TCP Composite Scaffolds with Excellent Osteogenic Performance DOI

Suyun Li,

Yanbo Shan,

Jingyi Chen

и другие.

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 27, 2025

Piezoelectricity is reported to be able promote bone scaffolds with excellent osteogenic performance. Herein, barium titanate/β-tricalcium phosphate (BTO/β-TCP) piezoelectric composite were 3D printed, and their performances investigated in detail. The fabrication of BTO/β-TCP employed cutting-edge DLP printing technology. scaffolds, featuring a triply periodic minimal surface (TPMS) design porosity 60%, offered unique structural framework. A comprehensive assessment the composition, properties, mechanical characteristics was conducted. Notably, an increase BTO volume fraction from 50 80 vol % within led reduction compressive strength, decreasing 2.47 1.74 MPa. However, this variation accompanied by substantial enhancement constant d33, soaring 1.4 pC/N 21.6 pC/N. Utilizing mouse osteoblasts (MC3T3-E1) live/dead cell staining assay, under influence external ultrasound, demonstrated commendable biocompatibility these ceramic scaffolds. Furthermore, thorough analyses alkaline phosphatase (ALP) activity polymerase chain reaction (PCR) findings provided compelling evidence scaffolds' superior underpinning effectiveness at cellular protein gene levels. In conclusion, study offers groundbreaking strategy for employment implant applications, harnessing blend biocompatibility, piezoelectricity, potential.

Язык: Английский

Процитировано

0

Piezoelectric Biomaterials for Use in Bone Tissue Engineering—A Narrative Review DOI Open Access
Sandeep Choudhury, Debaprasad Das, Sandipan Roy

и другие.

Journal of Biomedical Materials Research Part B Applied Biomaterials, Год журнала: 2025, Номер 113(4)

Опубликована: Март 17, 2025

ABSTRACT To examine natural bone's bioelectrical traits, notably its piezoelectricity, and to look into how these characteristics influence bone growth repair. In the context of exploring potential piezoelectric biomaterials, such as biopolymers bio‐ceramics, towards orthopedic regeneration applications, research seeks evaluate significance piezoelectricity‐driven osteogenesis. The paper reviews recent on electrical dielectric properties, surface polarization/electrical stimulation effects interacting with cell activity effectiveness biomaterials support tissues' regenerative process. study includes a number materials, collagen, polyvinylidene fluoride (PVDF) barium titanate. applications organic polymers, polymers are particularly highlighted. Piezoelectric being shown in studies enhance cellular metabolism vitro well promote tissues vivo, especially when paired electric field or interface polarization. bio‐ceramics like magnesium silicate titanate, collagen PVDF, have possibilities for applications. However, there several challenges regarding manufacturing specific compositions having desired properties. This review highlighted special emphasis bioceramics. Therefore, types materials huge because they can mimic properties allow better advances tissue engineering medicine. date, little is known about their mechanism action, modifications needed improve efficacy clinical uptake.

Язык: Английский

Процитировано

0

Advanced Vat Photopolymerization of Polymer-derived 70S30C Glass-Carbon Nano-Composites: Topological Control and Biological Validation DOI Creative Commons
Hamada Elsayed, Sara Micheli,

Franco Matías Stábile

и другие.

Journal of the European Ceramic Society, Год журнала: 2025, Номер unknown, С. 117384 - 117384

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

3D Printing of Polyester Scaffolds for Bone Tissue Engineering: Advancements and Challenges DOI Creative Commons

Mojtaba Salehabadi,

Hamid Mirzadeh

Advanced Materials Technologies, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 27, 2024

Abstract Polyesters have garnered significant attention in bone tissue engineering (BTE) due to their tunable degradation rates, biocompatibility, and convenient processing. This review focuses on recent advancements challenges the 3D printing of polyester‐based scaffolds for BTE. Various techniques, such as fused deposition modeling (FDM), selective laser sintering (SLS), vat photopolymerization (VP), Wet‐spun additive manufacturing, are explored, emphasizing ability construct with precise architectural control. The main printed polyester limited mechanical properties, lack inherent bioactivity, release acidic byproducts during biodegradation. Strategies enhance scaffold performance, incorporating bioactive ceramics growth factors, discussed, focusing improving osteoconductivity, osteoinductivity, strength. Recent studies integrating these components into techniques optimize porosity biodegradability presented. Finally, addresses ongoing issues, difficulty some biomolecules bioceramics improved clinical translation. comprehensive overview aims provide insight future directions potential solutions overcoming limitations 3D‐printed

Язык: Английский

Процитировано

1

Three-Dimensionally Printed Bionic Hydroxyapatite (HAp) Ceramic Scaffolds with Different Structures and Porosities: Strength, Biocompatibility, and Biomedical Application Potential DOI Open Access

Peng Zhang,

Qing Zhou, Rujie He

и другие.

Materials, Год журнала: 2024, Номер 17(24), С. 6092 - 6092

Опубликована: Дек. 13, 2024

Bionic bioceramic scaffolds are essential for achieving excellent implant properties and biocompatible behavior. In this study, inspired by the microstructure of natural bone, bionic hydroxyapatite (HAp) ceramic with different structures (body-centered cubic (BCC), face-centered (FCC), gyroid Triply Periodic Minimal Surfaces (TPMSs)) porosities (80 vol.%, 60 40 vol.%) were designed, 3D-printed, characterized. The effects structure porosity on morphology, mechanical properties, in vitro biocompatibility HAp studied compared each other. Interestingly, scaffold a 80 vol.% TPMS had best combination compressive strength biocompatibility, demonstrated great biomedical application potential bone repair. We hope study can provide reference development field repair engineering.

Язык: Английский

Процитировано

0