Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(7), С. 1662 - 1667
Опубликована: Янв. 25, 2019
Abstract
A
convenient
C−H
amination
of
quinoxalin‐2‐ones
has
been
developed.
This
transformation
provides
concise
access
to
3‐aminoquinoxalin‐2(1
H
)‐ones
with
a
broad
tolerance
functional
groups,
utilizing
TMSN
3
as
an
amino
source
under
simple
and
mild
conditions.
The
target
are
important
intermediates
for
the
synthesis
biologically
active
3‐
N
‐substituted
quinoxalin‐2‐one
derivatives.
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image
Organic & Biomolecular Chemistry,
Год журнала:
2019,
Номер
17(24), С. 5863 - 5881
Опубликована: Янв. 1, 2019
The
direct
C3-functionalization
of
quinoxalin-2(1H)-ones
via
C–H
bond
activation
has
recently
attracted
considerable
attention,
due
to
their
diverse
biological
activities
and
chemical
properties.
Green Chemistry,
Год журнала:
2020,
Номер
22(5), С. 1720 - 1725
Опубликована: Янв. 1, 2020
An
eco-friendly
visible-light-induced
decarboxylative
acylation
of
quinoxalin-2(1H)-ones
and
α-oxo
carboxylic
acids
with
air
as
the
oxidant
under
external-photocatalyst-free
conditions
was
established.
Organic Letters,
Год журнала:
2019,
Номер
21(12), С. 4698 - 4702
Опубликована: Июнь 6, 2019
The
first
example
of
oxidative
C–H
fluoroalkoxylation
quinoxalinones
with
fluoroalkyl
alcohols
under
transition-metal
and
solvent-free
conditions
is
described.
This
approach
provides
the
synthesis
fluoroalkoxylated
quinoxaline
derivatives
good
to
excellent
yields
mild
reactions
conditions.
method
can
also
be
extended
facile
efficient
histamine-4
receptor.
Green Chemistry,
Год журнала:
2020,
Номер
23(1), С. 374 - 378
Опубликована: Окт. 23, 2020
Aryl
radicals
were
generated
for
the
first
time
from
aryl
acyl
peroxides
in
ethyl
acetate
under
ambient
conditions
and
visible-light
illumination
absence
of
any
additive,
metal
catalyst,
or
external
photosensitizer.
Organic Chemistry Frontiers,
Год журнала:
2020,
Номер
7(3), С. 492 - 498
Опубликована: Янв. 1, 2020
Visible-light-mediated
procedure
has
been
developed
for
the
synthesis
of
3-acyl
quinoxalin-2(1H)-ones
through
acridine
red
catalyzed
decarboxylative
acylation
α-oxo-carboxylic
acids
with
quinoxalin-2(1H)-ones.
Green Chemistry,
Год журнала:
2019,
Номер
21(23), С. 6241 - 6245
Опубликована: Янв. 1, 2019
We
have
developed
a
metal-free
and
catalyst-free
visible-light-promoted
direct
C–H
sulfenylation
of
quinoxalin-2(1H)-ones
with
thiols
for
the
synthesis
diverse
3-sulfenylquinoxalin-2(1H)-ones.
Organic Chemistry Frontiers,
Год журнала:
2019,
Номер
6(8), С. 1173 - 1182
Опубликована: Янв. 1, 2019
A
facile
and
efficient
transition-metal-free
decarboxylative
radical
coupling
reaction
of
α,α-difluoroarylacetic
acids
with
quinoxalin-2(1H)-ones
has
been
developed
under
mild
conditions.
Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(23), С. 5490 - 5498
Опубликована: Сен. 16, 2019
Abstract
An
efficient
approach
using
a
photocatalytic
strategy
for
C−H
perfluoroalkylation
of
quinoxalinones
under
aerobic
oxidation
condition
has
been
developed.
Such
transformation
employs
readily
available
sodium
perfluoroalkanesulfinates
as
reagents
and
demonstrates
good
functional
group
compatibility,
affording
corresponding
products
in
moderate
to
yields.
Compared
with
previous
procedures,
this
protocol
uses
oxygen
oxidant,
avoids
the
use
external
additive.
A
radical
mechanism
is
involved
reaction.
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