Visible-light-induced reactions of methylenecyclopropanes (MCPs) DOI Creative Commons

Hao-Zhao Wei,

Min Shi, Yin Wei

и другие.

Chemical Communications, Год журнала: 2023, Номер 59(19), С. 2726 - 2738

Опубликована: Янв. 1, 2023

We describe recent achievements in the visible-light-induced chemical transformations of methylenecyclopropanes (MCPs), including ring-opening reactions, cyclopropane-producing and reactions via a non-classical radical clock.

Язык: Английский

Visible-Light-Mediated Two Transient C(sp3) Radical-Selective Cross-Coupling via Nickel Catalyst Continuous Capture: Synthesis of Pyrroline Derivatives DOI
Biao Yang, Xue‐Yang Wang,

Xie‐Tian Huang

и другие.

ACS Catalysis, Год журнала: 2023, Номер 13(23), С. 15331 - 15339

Опубликована: Ноя. 13, 2023

Two C(sp3) radicals cross-coupling as a straightforward method for constructing C(sp3)–C(sp3) bonds has attracted extensive attention from chemists. Unfortunately, the strategy is challenging due to unexpected reactions of transient radicals, such homocoupling and hydrogen atom transfer. In this regard, capturing open-shell by metal catalysts can effectively enhance selectivity radical via formation more stable organometallic intermediates. Herein, we disclose selective two through dual combination iridium-catalyst-mediated decarboxylation nickel-catalyst-mediated continuous capture radicals. This mild atom-efficient Ni-catalyzed N-cyclization–alkylation protocol was employed prepare various alkyl–alkyl cross-coupled products. The synthetic applications methodology are demonstrated late-stage functionalization drugs, natural products, biomolecules.

Язык: Английский

Процитировано

10
Copper-Catalyzed [3 + 2] Annulation of O-Acyl Oximes with 4-Sulfonamidophenols for the Synthesis of 5-Sulfonamidoindoles and 2-Amido-5-sulfonamidobenzofuran-3(2H)-ones DOI

Zi-Jun Hu,

Wei Chen,

Xinyu Lyu

и другие.

Organic Letters, Год журнала: 2024, Номер 26(20), С. 4229 - 4234

Опубликована: Май 13, 2024

A copper-catalyzed [3 + 2] annulation of

Язык: Английский

Процитировано

3
A general photochemical strategy for the oximation of activated alkenes without a catalyst DOI

Hongyan Lan,

You Su,

Y. Chen

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(15), С. 4207 - 4213

Опубликована: Янв. 1, 2024

A general photochemical approach for the oximation of activated alkenes to synthesize diverse oximes without catalysts is described. The simple and modular method offers a new perspective chemists rapidly obtain various radical intermediates.

Язык: Английский

Процитировано

3
DABCO‐Promoted Selective Photochemical C−N Coupling: Access to Unsymmetrical Azahelicenes DOI
R. Yu. Balakhonov, I. S. Mekeda, Валерий З. Ширинян

и другие.

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(21), С. 3690 - 3703

Опубликована: Сен. 16, 2023

Abstract A multifaceted study on the effect of various factors efficiency photocyclization naphthofuran O‐acyl oximes was performed. It showed that without any additives or in presence electron acceptors, reaction occurs by a radical pathway and with low chemoselectivity, while DABCO promotes intramolecular cyclization to give naphthofuroquinolines (NFQs) 34–87% yields. The iminyl formed under UV irradiation due single transfer (SET) N−O bond cleavage undergoes selective homolytic aromatic substitution (HAS) formation new C−N bond. This route quinoline‐annulated scaffolds is based use both as an agent proton acceptor.

Язык: Английский

Процитировано

9
Visible-light-induced reactions of methylenecyclopropanes (MCPs) DOI Creative Commons

Hao-Zhao Wei,

Min Shi, Yin Wei

и другие.

Chemical Communications, Год журнала: 2023, Номер 59(19), С. 2726 - 2738

Опубликована: Янв. 1, 2023

We describe recent achievements in the visible-light-induced chemical transformations of methylenecyclopropanes (MCPs), including ring-opening reactions, cyclopropane-producing and reactions via a non-classical radical clock.

Язык: Английский

Процитировано

8