Rhodium-catalyzed transformations of diazo compounds via a carbene-based strategy: recent advances DOI Creative Commons
Fatemeh Doraghi,

Parsa Baghershahi,

Mehran Ghasemi

и другие.

RSC Advances, Год журнала: 2024, Номер 14(53), С. 39337 - 39352

Опубликована: Янв. 1, 2024

As a carbene precursor, diazo compounds incorporate in Rh-catalyzed synthesis of heterocycles, carbocycles and functionalized compounds. The reaction involves C–H activation, insertion an annulation/functionalization sequence.

Язык: Английский

Substrate-Controlled Divergent Synthesis of Benzimidazole-Fused Quinolines and Spirocyclic Benzimidazole-Fused Isoindoles DOI Creative Commons

Ying‐Ti Huang,

Wan‐Wen Huang,

Yi‐Ting Huang

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(11), С. 7513 - 7520

Опубликована: Май 9, 2024

A Rh(III)-catalyzed annulation of 2-arylbenzimidazoles with α-diazo carbonyl compounds via C–H activation/carbene insertion/intramolecular cyclization is explored. The switchable product selectivity achieved by the use distinct compounds. Benzimidazole-fused quinolines are obtained through [4 + 2] exclusively when 2-diazocyclohexane-1,3-diones used, where they act as a C2 synthon. Alternatively, diazonaphthalen-1(2H)-ones merely function one-carbon unit synthon to generate quaternary center 1] afford spirocyclic benzimidazole-fused isoindole naphthalen-2-ones. thorough mechanistic study reveals course reaction.

Язык: Английский

Процитировано

3
Synthesis of 1,4-epoxy-2-aryltetrahydro-1-benzazepines via rhodium(iii)-catalyzed C–H allylation/intramolecular 1,3-dipolar cycloaddition DOI
Xuan Wang, Jianlong Li,

Haifang Du

и другие.

Chemical Communications, Год журнала: 2024, Номер 60(17), С. 2401 - 2404

Опубликована: Янв. 1, 2024

Herein, we report a new synthetic route to 1,4-epoxy-2-aryltetrahydro-1-benzazepine derivatives with high efficiency, namely the Rh(III)-catalyzed C-H allylation of nitrones allyl precursors, followed by subsequent intramolecular 1,3-dipolar cycloaddition, deliver title compounds. This reaction is regio- and stereo-selective, generating

Язык: Английский

Процитировано

1
Synthesis of Functionalized Indoles by an Iridium-Catalyzed N–H Insertion Cascade: Nucleophilic Cyclization of Naphthylamines with α-Diazocarbonyl Compounds DOI
Xiaogang Wang, Chi Yang, Di Chen

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 28, 2024

A novel iridium-catalyzed [3 + 2] annulation of naphthylamines and α-diazocarbonyl compounds was developed for the rapid assembly densely functionalized indoles. This new catalytic process represents first example a cascade intramolecular nucleophilic cyclization by N-H insertion amines. Various could be obtained in high yields with excellent functional group tolerance. The reaction affords valuable indole derivatives, enabling expedient access to heterocyclic analogues not easily accessible other methods.

Язык: Английский

Процитировано

1
Rhodium-catalyzed transformations of diazo compounds via a carbene-based strategy: recent advances DOI Creative Commons
Fatemeh Doraghi,

Parsa Baghershahi,

Mehran Ghasemi

и другие.

RSC Advances, Год журнала: 2024, Номер 14(53), С. 39337 - 39352

Опубликована: Янв. 1, 2024

As a carbene precursor, diazo compounds incorporate in Rh-catalyzed synthesis of heterocycles, carbocycles and functionalized compounds. The reaction involves C–H activation, insertion an annulation/functionalization sequence.

Язык: Английский

Процитировано

1