Exploring nickel-catalyzed organochalcogen synthesis via cross-coupling of benzonitrile and alkyl chalcogenols with computational tools DOI
Francisco A. Gómez-Mudarra, Gabriel Aullón, Jesús Jover

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 30, 2024

The reaction mechanism of Ni(0)-catalyzed C–S cross-coupling between benzonitrile and propanethiol has been studied with DFT validated by microkinetic modeling. protocol is used to assess its potential usage for building C–Se C–Te bonds.

Язык: Английский

Photoinduced Formation of Cubyl Aryl Thioethers and Synthesis of Monocubyl Analogue of Dapsone DOI

Laly Donnier-Valentin,

Seydou Kassamba,

Julien Legros

и другие.

Organic Letters, Год журнала: 2023, Номер 25(48), С. 8580 - 8584

Опубликована: Ноя. 21, 2023

1,4-Disubstituted cubyl aryl thioethers were generated from the corresponding iodocubanes and thiolates upon UV irradiation in dimethyl sulfoxide at room temperature. This simple procedure was found to be compatible with a variety of substituted thiolates. finding paved way synthesis monocubyl analogue dapsone, key molecule treatment leprosy, also known as Hansen's disease, acne.

Язык: Английский

Процитировано

2
Photoredox-catalyzed cascade [2+2+1] cyclization of 1,6-enynes with thiols DOI Creative Commons
Zhe Meng, Min Shi, Yin Wei

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(12), С. 3442 - 3450

Опубликована: Янв. 1, 2024

Here, we report a visible-light-mediated [2 + 2 1] cascade cyclization of 1,6-enynes with thiols, providing sulfur-containing polycyclic molecules in moderate to good yields.

Язык: Английский

Процитировано

0
A Continuous Flow Protocol for the Synthesis of Alkenyl Thioethers Based on the Photochemical Activation of Halogen-Bonding Complexes DOI
Manuel Plaza, Helena F. Piedra, Carlos Valdés

и другие.

Synlett, Год журнала: 2024, Номер unknown

Опубликована: Июнь 15, 2024

Abstract We report a useful flow protocol for the preparation of alkenyl thioethers from bromides and thiols in basic media with visible-light irradiation. The reactions exhibit wide functional-group tolerance, proceed under mild conditions, are stereoselective, do not require use catalysts. transformations can be successfully scaled up to 5 mmol scale without compromising yield. key success these is photochemical excitation halogen-bonding complexes form sulfur-centered radicals, recently developed our laboratories.

Язык: Английский

Процитировано

0
Exploring nickel-catalyzed organochalcogen synthesis via cross-coupling of benzonitrile and alkyl chalcogenols with computational tools DOI
Francisco A. Gómez-Mudarra, Gabriel Aullón, Jesús Jover

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 30, 2024

The reaction mechanism of Ni(0)-catalyzed C–S cross-coupling between benzonitrile and propanethiol has been studied with DFT validated by microkinetic modeling. protocol is used to assess its potential usage for building C–Se C–Te bonds.

Язык: Английский

Процитировано

0