Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 30, 2024
The
reaction
mechanism
of
Ni(0)-catalyzed
C–S
cross-coupling
between
benzonitrile
and
propanethiol
has
been
studied
with
DFT
validated
by
microkinetic
modeling.
protocol
is
used
to
assess
its
potential
usage
for
building
C–Se
C–Te
bonds.
Organic Letters,
Год журнала:
2023,
Номер
25(48), С. 8580 - 8584
Опубликована: Ноя. 21, 2023
1,4-Disubstituted
cubyl
aryl
thioethers
were
generated
from
the
corresponding
iodocubanes
and
thiolates
upon
UV
irradiation
in
dimethyl
sulfoxide
at
room
temperature.
This
simple
procedure
was
found
to
be
compatible
with
a
variety
of
substituted
thiolates.
finding
paved
way
synthesis
monocubyl
analogue
dapsone,
key
molecule
treatment
leprosy,
also
known
as
Hansen's
disease,
acne.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(12), С. 3442 - 3450
Опубликована: Янв. 1, 2024
Here,
we
report
a
visible-light-mediated
[2
+
2
1]
cascade
cyclization
of
1,6-enynes
with
thiols,
providing
sulfur-containing
polycyclic
molecules
in
moderate
to
good
yields.
Abstract
We
report
a
useful
flow
protocol
for
the
preparation
of
alkenyl
thioethers
from
bromides
and
thiols
in
basic
media
with
visible-light
irradiation.
The
reactions
exhibit
wide
functional-group
tolerance,
proceed
under
mild
conditions,
are
stereoselective,
do
not
require
use
catalysts.
transformations
can
be
successfully
scaled
up
to
5
mmol
scale
without
compromising
yield.
key
success
these
is
photochemical
excitation
halogen-bonding
complexes
form
sulfur-centered
radicals,
recently
developed
our
laboratories.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 30, 2024
The
reaction
mechanism
of
Ni(0)-catalyzed
C–S
cross-coupling
between
benzonitrile
and
propanethiol
has
been
studied
with
DFT
validated
by
microkinetic
modeling.
protocol
is
used
to
assess
its
potential
usage
for
building
C–Se
C–Te
bonds.