Catalyst-Free Radical Dearomatization of Phenols with Aryldiazonium Tetrafluoroborates and DABCO·(SO2)2 DOI
Xingxian Zhang, Guanyinsheng Qiu, Shaoyu Li

и другие.

Synlett, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Abstract A catalyst-free, three-component dearomatization of phenols with aryldiazonium tetrafluoroborates and DABCO·(SO2)2 has been developed for the synthesis 4-(arylsulfonyl)cyclohex-2,5-dien-1-one scaffolds. This method offers mild reaction conditions high step efficiency, providing a green efficient strategy phenols. Mechanistic studies indicated that this transformation relies on tandem radical sulfur dioxide insertion process.

Язык: Английский

β-Thioamide Sulfone Enabled Copper-Catalyzed Ring-Opening/Sulfonylation of Cyclopropenes: Access to Alkyl Aryl Sulfones DOI

Arshad Ali,

C.‐S. CHUNG, Jingru Wang

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Янв. 9, 2025

Sulfone motifs play important roles in bioactive compounds and functional materials. The development of efficient methodologies for constructing sulfonyl-containing has thus attracted considerable attention. Here, we introduce a protocol the preparation alkyl aryl sulfones under mild conditions. This employs β-thioamide sulfone as novel motif donor. It forms sulfinates situ basic conditions, which then undergo cross-coupling with intermediates that were generated from ligand-free copper-catalyzed cyclopropenes (CPEs) ring opening.

Язык: Английский

Процитировано

0

Catalyst-Free Radical Dearomatization of Phenols with Aryldiazonium Tetrafluoroborates and DABCO·(SO2)2 DOI
Xingxian Zhang, Guanyinsheng Qiu, Shaoyu Li

и другие.

Synlett, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Abstract A catalyst-free, three-component dearomatization of phenols with aryldiazonium tetrafluoroborates and DABCO·(SO2)2 has been developed for the synthesis 4-(arylsulfonyl)cyclohex-2,5-dien-1-one scaffolds. This method offers mild reaction conditions high step efficiency, providing a green efficient strategy phenols. Mechanistic studies indicated that this transformation relies on tandem radical sulfur dioxide insertion process.

Язык: Английский

Процитировано

0