Smart Sensors and Microtechnologies in the Precision Medicine Approach against Lung Cancer DOI Creative Commons
Giulia Maria Stella, Sara Lettieri, Davide Piloni

и другие.

Pharmaceuticals, Год журнала: 2023, Номер 16(7), С. 1042 - 1042

Опубликована: Июль 22, 2023

Background and rationale. The therapeutic interventions against lung cancer are currently based on a fully personalized approach to the disease with considerable improvement of patients’ outcome. Alongside continuous scientific progresses research investments, massive technologic efforts, innovative challenges, consolidated achievements together investments at bases engineering manufacturing revolution that allows significant gain in clinical setting. Aim methods. scope this review is thus focus, rather than biologic traits, analysis precision sensors novel generation materials, as semiconductors, which below development diagnosis treatment. In perspective, careful revision state art literature experimental knowledge presented. Results. Novel materials being used treatment for cancer. Among them, semiconductors analyze volatile compounds allow early diagnosis. Moreover, they can be generate MEMS have found an application advanced imaging techniques well drug delivery devices. Conclusions. Overall, these issues represent critical only partially known generally underestimated by community. These micro-technology-based biosensing devices, use molecules atomic concentrations, crucial innovation since allowed recent advances biology deciphering detection therapy. There urgent need create stronger dialogue between technologists, basic researchers, clinicians address all efforts towards real Here, great attention focused their cancer, from exploitations translational development, ensure better outcomes.

Язык: Английский

A skin disease classification model based on multi scale combined efficient channel attention module DOI Creative Commons
Hui Liu, Yibo Dou, Kai Wang

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 19, 2025

Skin diseases, a significant category in the medical field, have always been challenging to diagnose and high misdiagnosis rate. Deep learning for skin disease classification has considerable value clinical diagnosis treatment. This study proposes model based on multi-scale channel attention. The network architecture of consists three main parts: an input module, four processing blocks, output module. Firstly, improved pyramid segmentation attention module extract features image entirely. Secondly, reverse residual structure is used replace backbone network, integrated into achieve better feature extraction. Finally, adaptive average pool fully connected layer, which convert aggregated global several categories generate final task. To verify performance proposed model, this two commonly datasets, ISIC2019 HAM10000, validation. experimental results showed that accuracy was 77.6 $$\%$$ series dataset 88.2 HAM10000 dataset. External validation data added evaluation validate further, comprehensive proved effectiveness paper.

Язык: Английский

Процитировано

1

Self‐Sustaining Triboelectric Nanosensors for Real‐Time Urine Analysis in Smart Toilets DOI Creative Commons
Indrajit Mondal, Elias Mansour, Youbin Zheng

и другие.

Small, Год журнала: 2024, Номер 20(42)

Опубликована: Июнь 21, 2024

Healthcare has undergone a revolutionary shift with the advent of smart technologies, and toilets (STs) are among innovative inventions offering non-invasive continuous health monitoring. The present technical challenges toward this development include limited sensitivity integrated sensors, poor stability, slow response requirement external energy supply alongside manual sample collection. In article, triboelectric nanosensor array (TENSA) is introduced featuring electrodes crafted from laser-induced 3D graphene functional polymers like polystyrene, polyimide, polycaprolactone for real-time urine analysis while generating 50 volts output via droplet-based triboelectrification. Though modulating interfacial double-layer capacitance, these sensors exhibit exceptional selectivity in detecting broad spectrum urinary biomarkers, including ions, glucose, urea classification precision 95% concentration identification accuracy up to 0.97 (R

Язык: Английский

Процитировано

6

Synergistic convergence of materials and enzymes for biosensing and self-sustaining energy devices towards on-body health monitoring DOI Creative Commons
Suntisak Khumngern, Itthipon Jeerapan

Communications Materials, Год журнала: 2024, Номер 5(1)

Опубликована: Июль 24, 2024

Abstract Wearable enzyme-based biosensors enable advanced healthcare diagnostics through the monitoring of biomarkers and physiological states. The integration materials engineering enzyme conjugation has established groundwork for advancements in modern analytical chemistry, poised to extend frontiers wearable biosensing further. Recent enzymatic biofuel cells have also enhanced devices by harnessing biofuels, such as glucose lactate biofluids. Importantly, offer potential self-powered biosensors. Here, we present an overview principles considerations associated with integrating enzymes electrodes achieve effective self-sustaining cell-based energy systems. Furthermore, discuss challenges encountered sensors cells. Representative applications settings are highlighted, along a summary real sample analyses, emphasizing concentration ranges analytes actual sweat samples underscore their relevance real-world scenarios. Finally, discussion explores anticipated impact future material innovations integrations on development next-generation biodevices.

Язык: Английский

Процитировано

5

A novel cell-free therapy using exosomes in the inner ear regeneration DOI

Masoumeh Amiri,

Mohammad Amin Kaviari, Gelavizh Rostaminasab

и другие.

Tissue and Cell, Год журнала: 2024, Номер 88, С. 102373 - 102373

Опубликована: Апрель 9, 2024

Язык: Английский

Процитировано

3

Advancements in Breathomics: Special Focus on Electrochemical Sensing and AI for Chronic Disease Diagnosis and Monitoring DOI Creative Commons

Nikini Rashmithara Subawickrama Mallika Widanaarachchige,

Anirban Paul, Ivneet Banga

и другие.

ACS Omega, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

This Review examines the potential of breathomics in enhancing disease monitoring and diagnostic precision when integrated with artificial intelligence (AI) electrochemical sensing techniques. It discusses breathomics' for early noninvasive diagnosis a focus on chronic kidney (CKD), obstructive pulmonary (COPD), lung cancer, which have been well studied context VOC association diseases. The nature exhaled breath analysis can be advantageous compared to traditional methods CKD, often rely blood urine testing. enhance spirometry imaging used COPD diagnosis, providing more comprehensive picture disease's progression. Breathomics could also provide less intrusive potentially earlier approach is now dependent biopsy. combination breathomics, sensing, AI lead personalized successful treatment plans illnesses using algorithms decipher complicated patterns. assesses viability effectiveness combining sensors by synthesizing recent research findings technological developments.

Язык: Английский

Процитировано

0

An Intuitive and Modular Framework for Enhanced Human-Machine Synergy DOI
Manju Kashyap,

Apoorva Patel,

Ashish Kumar

и другие.

Lecture notes in networks and systems, Год журнала: 2025, Номер unknown, С. 53 - 65

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Sensor-based prevention of falls and pressure ulcers: A scoping review DOI Creative Commons
Anna Katharina Winkler, Martin Pallauf, Simon Krutter

и другие.

International Journal of Medical Informatics, Год журнала: 2025, Номер unknown, С. 105878 - 105878

Опубликована: Март 1, 2025

Falls and pressure ulcers are serious complications impacting care quality in nursing homes. Sensor technologies can help prevent these adverse events through continuous monitoring timely intervention. This scoping review, following JBI guidelines, evaluated the effects of sensor-based fall ulcer prevention long-term experiences patients healthcare professionals. The review included primary studies, reviews, protocols published from 2014 to 2023. Screening, data extraction, appraisal were conducted independently by two authors using MMAT tools. A total 31 studies included: 22 on prevention, eight one addressing both. User-based sensors effective preventing both falls ulcers. Accelerometers enhanced sensitivity for detection adherence repositioning protocols. Context-based sensors, such as Doppler, webcams, Kinect, showed variable precision false alarm rates, while range demonstrated high precision. accelerometers promising but provided inconsistent data. Additional manual assessments sensor accuracy. Patients preferred non-obtrusive, user-friendly professionals emphasized need seamless integration into routines. Both groups valued real-time alert capabilities, though privacy security remained concerns. show potential enhancing patient safety care, further refinement is needed context-based prevention. Integrating with standard improve outcomes, ethical issues essential broader acceptance.

Язык: Английский

Процитировано

0

An end-to-end four tier remote healthcare monitoring framework using edge-cloud computing and redactable blockchain DOI
Naif Alsharabi, Abdulaziz M. Alayba, Gharbi Alshammari

и другие.

Computers in Biology and Medicine, Год журнала: 2025, Номер 189, С. 109987 - 109987

Опубликована: Март 12, 2025

Язык: Английский

Процитировано

0

The Next Generation of Health Monitoring DOI
Wasswa Shafik

Advances in computational intelligence and robotics book series, Год журнала: 2025, Номер unknown, С. 69 - 106

Опубликована: Март 28, 2025

Digital twins and medical wearables are revolutionizing healthcare by enabling personalized, real-time monitoring predictive insights. twins, virtual replicas of patients, integrate data from to simulate health conditions, predict outcomes, optimize treatments. Medical such as smartwatches, biosensors, fitness trackers collect continuous data, providing insights into vital signs, activity levels, chronic disease management. Together, they enhance remote patient monitoring, support AI-driven diagnostics, facilitate early detection anomalies. This synergy accelerates precision medicine, improves empowers proactive healthcare, marking a transformative leap in innovation.

Язык: Английский

Процитировано

0

“First, Do No Harm” in the Digital Era: Examining the Practicality of the European Health Data Space Proposal and Ethical Implications of Artificial Intelligence. A Systematic Literature Review DOI
Ana Rita Ferreira,

Irina Alho,

Ana Luísa Neves

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0