Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 231 - 252
Опубликована: Ноя. 1, 2024
Язык: Английский
Biomedicines, Год журнала: 2024, Номер 12(1), С. 123 - 123
Опубликована: Янв. 7, 2024
Lung cancer demands innovative approaches for early detection and targeted treatment. In addressing this urgent need, exosomes play a pivotal role in revolutionizing both the treatment of lung cancer. Their remarkable capacity to encapsulate diverse range biomolecules, traverse biological barriers, be engineered with specific targeting molecules makes them highly promising diagnostic markers precise drug delivery cells. Furthermore, an in-depth analysis exosomal content biogenesis offers crucial insights into molecular profile tumors. This knowledge holds significant potential development therapies strategies Despite notable progress field, challenges standardization cargo loading persist. Collaborative research efforts are imperative maximize advance field precision medicine benefit patients.
Язык: Английский
Процитировано
32
Medical Oncology, Год журнала: 2025, Номер 42(5)
Опубликована: Март 25, 2025
Язык: Английский
Процитировано
1
European Journal of Medicinal Chemistry Reports, Год журнала: 2024, Номер 12, С. 100202 - 100202
Опубликована: Авг. 13, 2024
Metronidazole (MTZ) is a vital antimicrobial agent widely used in the treatment of various infections. However, its limited bioavailability and associated side effects necessitate development efficient drug delivery systems to enhance therapeutic efficacy minimize adverse reactions. The field nanotechnology nanomaterials presents promising solutions for delivering MTZ, leveraging their unique properties overcome these challenges. This comprehensive review explores variety nanomaterial-based approaches MTZ delivery, emphasizing benefits such as improved stability, targeted release, enhanced bioavailability. Various nanocarrier systems, including polymeric nanoparticles, lipid-based nanocarriers, inorganic are evaluated potential applications. underscores strategies aimed at reducing MTZ's through controlled release with nanocarriers facilitating sustained fluctuations concentrations potentially mitigate reactions linked administration. Furthermore, innovative combination therapies involving other drugs investigated ability outcomes combat resistance. Co-delivery show promise synergistically targeting infections while overall dosage effects. By summarizing latest advancements this provides valuable insights into nanotechnology-based optimizing therapy. These have transform offering safer more effective treatments infectious diseases, improving patient by
Язык: Английский
Процитировано
6
Journal of Nanobiotechnology, Год журнала: 2024, Номер 22(1)
Опубликована: Июнь 18, 2024
Abstract The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal strategy the pursuit refined treatment methodologies for pulmonary disorders. This review discusses utilization nanomaterial-assisted tools techniques to promote development more precise efficient treatments diseases. First, we briefly outline characterization respiratory system succinctly describe principal applications diverse lung ailment treatment. Second, elaborate on gene-editing tools, their configurations, assorted delivery methods, while delving into present state nanomaterial-facilitated interventions spectrum Subsequently, expound its deployment biomedicine, focusing research advances diagnosis conditions against backdrop coronavirus disease 2019 pandemic. Finally, summarize extant lacunae current delineate prospects advancement this domain. holistic approach augments pioneering solutions treatment, thereby endowing patients with efficacious personalized therapeutic alternatives.
Язык: Английский
Процитировано
5
Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 102, С. 106346 - 106346
Опубликована: Ноя. 6, 2024
Язык: Английский
Процитировано
4
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 153 - 189
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Advanced Therapeutics, Год журнала: 2025, Номер unknown
Опубликована: Март 3, 2025
Abstract The rise of antibiotic‐resistant bacteria, driven by antibiotic misuse, is a major global health threat. Addressing this issue requires understanding resistance mechanisms and developing innovative solutions. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)‐associated systems (Cas), genome‐editing tool derived from prokaryotic defense mechanisms, offers precise targeting genes. By reprogramming CRISPR‐Cas, bacteria can be killed or resensitized to antibiotics through plasmid curing. However, clinical applications face challenges, particularly in delivering CRISPR‐Cas components effectively. Nanotechnology has emerged as promising approach for targeted delivery tissues cells. This paper explores the molecular resistance, emphasizing structure function their mechanisms. It highlights use nanoparticles (NPs) nanoscale carriers deliver components, reviewing recent studies that combine NPs CRISPR target Additionally, discusses current challenges future prospects field, underscoring potential nanotechnology combat resistance.
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 201 - 221
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 177 - 199
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Breast Cancer Research and Treatment, Год журнала: 2025, Номер 211(3), С. 561 - 580
Опубликована: Апрель 17, 2025
Язык: Английский
Процитировано
0