Recent advances and new trends in the use of deep eutectic solvents in organic synthesis and other applications
Journal of Molecular Liquids,
Год журнала:
2025,
Номер
unknown, С. 127510 - 127510
Опубликована: Апрель 1, 2025
Язык: Английский
A Review on Supercapacitors: Development Trends, Challenges, and Future Perspectives
Next research.,
Год журнала:
2025,
Номер
unknown, С. 100228 - 100228
Опубликована: Март 1, 2025
Язык: Английский
Immune Checkpoint Inhibitors in Therapeutics and their Adverse Effect Profile: A Review
The Open Biomedical Engineering Journal,
Год журнала:
2025,
Номер
19(1)
Опубликована: Май 2, 2025
Objective
Immune
Checkpoint
Inhibitors
(ICIs)
have
transformed
the
field
of
oncology
by
improving
capacity
immune
system
to
combat
malignancies.
This
review
investigates
mechanisms
ICIs,
their
adverse
effects,
resistance
mechanisms,
and
role
Artificial
Intelligence
(AI)
And
Machine
Learning
(ML)
in
predicting
treatment
outcomes.
Methods
Materials
A
literature
search
was
conducted
using
PubMed,
Google
Scholar,
Web
Science
identify
pertinent
studies,
clinical
trials,
articles.
The
study
concentrated
on
seven
ICIs
that
been
approved
are
designed
target
PD-1,
PD-L1,
CTLA-4
pathways.
data
were
derived
from
guidelines
expert
opinions.
Results
illustrated
efficacy
a
variety
malignancies,
such
as
renal
cell
carcinoma,
non-small
lung
cancer,
melanoma.
Their
utilization,
whether
monotherapy
or
conjunction
with
chemotherapy,
radiotherapy,
targeted
therapies,
has
substantially
enhanced
survival.
Nevertheless,
management
Immune-Related
Adverse
Events
(irAEs)
affect
multiple
organ
systems
is
imperative.
In
certain
patients,
ICI
also
restricted
mechanisms.
AI/ML-driven
models
demonstrate
potential
for
anticipating
patient
responses,
optimizing
strategies,
reducing
toxicity
risks.
Conclusion
revolutionized
cancer
therapy;
however,
there
still
obstacles
responses
managing
effects.
emphasizes
innovative
use
AI/ML
improve
precision
safety
ICI.
additional
research
required
due
absence
reliable
predictive
biomarkers
variability
responses.
order
enhance
outcomes
reduce
toxicity,
future
should
AI-driven
incorporate
multi-omics
approaches.
Язык: Английский
Vapor Pressure of Ionic Liquids with a Common Tetrabutylammonium Cation and Three Different Anions
Applied Sciences,
Год журнала:
2025,
Номер
15(11), С. 6040 - 6040
Опубликована: Май 27, 2025
The
vapor
pressures,
pv,
of
three
ionic
compounds
used
as
starting
materials
deep
eutectic
systems,
namely,
tetrabutylammonium
bromide
(TBA-Br),
trifluoromethanesulfonate
(TBA-TFO),
and
bis(trifluoromethanesulfonyl)imide
(TBA-NTF2),
were
measured
using
isothermal
thermogravimetry.
TBA-Br
displays
large
values
reaching
≈700
Pa
at
170
°C.
TBA-NTF2
is
the
less
volatile
liquid,
with
a
pressure
≈1
240
°C,
while
TBA-TFO
has
slightly
higher
value
about
3
same
temperature.
pv
for
NTF2-containing
compound
are
comparable
to
those
liquids
containing
anion.
obtained
mean
vaporization
enthalpy,
ΔHvap,
(≈170
kJ
mol−1)
than
(≈145
mol−1).
enthalpy
fall
within
typical
range
observed
liquids.
Язык: Английский
Synthesis of copper hexaferrite magnetic nanoparticles based on carboxymethyl cellulose modified with polyacrylic acid (CMC/PAA/CuFe12O19) for loading and release of Levothyroxine
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
282, С. 137040 - 137040
Опубликована: Окт. 30, 2024
Язык: Английский