Electrochemical detection of ascorbic acid in artificial sweat using a flexible alginate/CuO-modified electrode

Microchimica Acta, Год журнала: 2020, Номер 187(9)

Опубликована: Авг. 27, 2020

Abstract A flexible sensor is presented for electrochemical detection of ascorbic acid in sweat based on single-step modified gold microelectrodes. The modification consists electrodeposition alginate membrane with trapped CuO nanoparticles. electrodes are fabricated at a thin polyimide support and the soft nature can withstand mechanical stress beyond requirements skin monitoring. After characterization via optical scanning electron microscopy cyclic voltammetry, oxidative properties exploited toward amperometric measurement micromolar levels neutral buffer acidic artificial sweat, ultralow applied potential (− 5 mV vs. Au pseudo-reference electrode). Alternatively, horizontal shift redox peaks by voltammetry also possible. Obtaining limit 1.97 μM, sensitivity 0.103 V log (μM) −1 peak shift, linear range 10–150 effect possible interfering species present minimized, no observable cross-reaction, thus maintaining high degree selectivity despite absence enzymes fabrication scheme. With lateral flow approach sample delivery, repeated measurements show recovery few seconds, relative standard deviation about 20%, which serve to detect increased loss or vitamin, yet be improved future optimized device designs. This envisioned as promising component wearable devices e.g. non-invasive monitoring micronutrient through comprising features light weight, low cost, easy needed such application.

Язык: Английский

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Rapid and quantitative detection of tear MMP-9 for dry eye patients using a novel silicon nanowire-based biosensor

Biosensors and Bioelectronics, Год журнала: 2022, Номер 214, С. 114498 - 114498

Опубликована: Июнь 26, 2022

Язык: Английский

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Functional Devices from Bottom-Up Silicon Nanowires: A Review

Nanomaterials, Год журнала: 2022, Номер 12(7), С. 1043 - 1043

Опубликована: Март 22, 2022

This paper summarizes some of the essential aspects for fabrication functional devices from bottom-up silicon nanowires. In a first part, different ways exploiting nanowires in devices, single to large assemblies such as nanonets (two-dimensional arrays randomly oriented nanowires), are briefly reviewed. Subsequently, main properties discussed followed by those that benefit numbers involved. After describing techniques used growth nanowires, context device fabrication, nanowire manipulation largely presented they constitute one fundamental steps allows positioning necessary start integration process. The advantages and disadvantages each these discussed. Then, families nanowire-based transistors presented; their most common routes electrical performance resulting also compared order highlight relevance geometries. Because can be bottlenecks, key technological elements detailed: sintering technique, importance surface interface engineering, role silicidation good performance. Finally application areas

Язык: Английский

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Multi-terminal ionic-gated low-power silicon nanowire synaptic transistors with dendritic functions for neuromorphic systems

Nanoscale, Год журнала: 2020, Номер 12(30), С. 16348 - 16358

Опубликована: Янв. 1, 2020

Neuromorphic computing systems have shown powerful capability in tasks, such as recognition, learning, classification and decision-making, which are both challenging inefficient using the traditional computation architecture.

Язык: Английский

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Porphyrins-based multidimensional nanomaterials: Structural design, modification and applications

Coordination Chemistry Reviews, Год журнала: 2024, Номер 523, С. 216264 - 216264

Опубликована: Окт. 16, 2024

Язык: Английский

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Silicon Nanowires and Their Impact on Cancer Detection and Monitoring

ACS Applied Nano Materials, Год журнала: 2020, Номер 3(9), С. 8522 - 8536

Опубликована: Авг. 3, 2020

Since the inception of silicon nanowire (SiNW)-based biosensors in 2001, SiNWs have been employed various detection schemes and routinely demonstrated capability for label-free, real-time, sub-femtomolar both protein nucleic acid analytes. This has allowed SiNW-based to integrate into field cancer monitoring thus potential be a paradigm shift how biomarkers are detected monitored. Combining this with several promising fields such as liquid biopsies targeted oncology, SiNW based represent an opportunity treatment more dynamic process. Such advances can provide clinicians information shorter time frame on molecular landscape patients, which better inform guidelines.

Язык: Английский

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Process Variability in Top-Down Fabrication of Silicon Nanowire-Based Biosensor Arrays

Sensors, Год журнала: 2021, Номер 21(15), С. 5153 - 5153

Опубликована: Июль 29, 2021

Silicon nanowire field-effect transistors (SiNW-FET) have been studied as ultra-high sensitive sensors for the detection of biomolecules, metal ions, gas molecules and an interface biological systems due to their remarkable electronic properties. “Bottom-up” or “top-down” approaches that are used fabrication SiNW-FET respective limitations in terms technology development. The “bottom-up” approach allows synthesis silicon nanowires (SiNW) range from a few nm hundreds diameter. However, it is technologically challenging realize reproducible bottom-up devices on large scale clinical biosensing applications. top-down involves state-of-the-art lithography nanofabrication techniques cast SiNW down 10s nanometers diameter out high-quality Silicon-on-Insulator (SOI) wafers controlled environment, enabling large-scale myriad possibility wafer-scale integration standard semiconductor processes makes SiNW-FETs one most promising candidates next generation biosensor platforms applications healthcare medicine. Although advanced employed fabricating SiNW, sensor-to-sensor variation limiting factors production towards commercial To provide detailed overview technical aspects responsible this variation, we critically review discuss fundamental could lead such focusing parameters described literature. Furthermore, impact functionalization aspects, surface modification, system biosensors post-fabrication-induced variations experiments.

Язык: Английский

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Review of the gas breakdown physics and nanomaterial-based ionization gas sensors and their applications

Plasma Sources Science and Technology, Год журнала: 2021, Номер 31(3), С. 033001 - 033001

Опубликована: Дек. 21, 2021

Abstract Ionization gas sensors are ubiquitous tools that can monitor desired gases or detect abnormalities in real time to protect the environment of living organisms maintain clean and/or safe industries. The sensors’ working principle is based on fingerprinting breakdown voltage one more target using nanostructured materials. Fundamentally, nanomaterial-based ionization-gas operate within a large framework physics; signifying an overall understanding mechanism crucial factor technological development ionization sensors. Moreover, many studies have revealed physical properties nanomaterials play decisive roles physics and performance plasma-based Based this insight, review provides comprehensive description foundation both ionization-gas-sensor technology, as well introduces research trends reviewed, including classical Townsend discharge theory modified Paschen curves; nanomaterial-based-electrodes proposed improve introduced. secondary electron emission at electrode surface key plasma–surface process affects Finally, we present our perspectives possible future directions.

Язык: Английский

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Self-Assembled Au Nanoparticle Monolayers on Silicon in Two- and Three-Dimensions for Surface-Enhanced Raman Scattering Sensing

ACS Applied Nano Materials, Год журнала: 2022, Номер 5(8), С. 11839 - 11851

Опубликована: Авг. 15, 2022

Gold nanoparticle/silicon composites are canonical substrates for sensing applications because of their geometry-dependent physicochemical properties and high activity via surface-enhanced Raman spectroscopy (SERS). The self-assembly gold nanoparticles (AuNPs) synthesized wet-chemistry on functionalized flat silicon (Si) vertically aligned Si nanowire (VA-SiNW) arrays is a simple cost-effective approach to prepare such substrates. Herein, we report the critical parameters that influence nanoparticle coverage, aggregation, assembly sites in two- three-dimensions with homogeneous optical SERS activity. We show degree AuNP aggregation depends silane used functionalization, while coverage can be adjusted by incubation time solution, both which directly affect substrate properties. In particular, reproducible synthesis nearly touching chain monolayers where AuNPs separated nanoscale gaps, likely formed due capillary forces generated during drying process. Such substrates, when sensing, produce uniform large enhancement signal density hot spots they provide. also controlled VA-SiNW arrays, provide even higher enhancement. directed specific regions SiNWs control over NP monolayer morphology (i.e., isolated vs NPs) demonstrated, together its resulting

Язык: Английский

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Metastable Group IV Allotropes and Solid Solutions: Nanoparticles and Nanowires

Chemistry of Materials, Год журнала: 2020, Номер 32(7), С. 2703 - 2741

Опубликована: Март 16, 2020

In the past decades, group IV nanowires and nanoparticles have been subject of extensive research. Beside tremendous progress in morphological control integration advanced device architectures, research on allotropes metastable compositions has gained considerable interest. Several new approaches now allow controlled formation specific nanostructured form as well chemical not attainable by traditional synthesis protocols. The conditions applied to these solid solutions are usually far from thermodynamic equilibrium or rely unconventional templates. increased interest field nanostructures arises their altered physical properties, including tunable, direct bandgaps with energies equivalent near- mid-infrared spectral region described for materials such Ge1–xSnx hexagonal Si1–xGex. implementation material characteristics complementary metal oxide semiconductor (CMOS) processes desirable applications electronics, optoelectronics, sensors, optics, etc. but also use nonsurface bound sensing, nanobiotechnology nanomedicine can offer additional opportunities. This review article highlights both important advancements still open questions continued development nanoscaled next-generation concepts.

Язык: Английский

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