Light from Afield: Fast, High-Resolution, and Layer-Free Deep Vat 3D Printing DOI Creative Commons
Parth Chansoria, Riccardo Rizzo, Dominic Rütsche

и другие.

Chemical Reviews, Год журнала: 2024, Номер 124(14), С. 8787 - 8822

Опубликована: Июль 5, 2024

Harnessing light for cross-linking of photoresponsive materials has revolutionized the field 3D printing. A wide variety techniques leveraging broad-spectrum shaping have been introduced as a way to achieve fast and high-resolution printing, with applications ranging from simple prototypes biomimetic engineered tissues regenerative medicine. Conventional light-based printing use material in layer-by-layer fashion produce complex parts. Only recently, new emerged which deploy multidirection, tomographic, light-sheet or filamented image projections deep into volume resin-filled vat photoinitiation cross-linking. These Deep Vat (DVP) approaches alleviate need layer-wise enable unprecedented fabrication speeds (within few seconds) high resolution (>10 μm). Here, we elucidate physics chemistry these processes, their commonalities differences, well emerging biomedical non-biomedical fields. Importantly, highlight limitations, future scope research that will improve scalability applicability DVP engineering medicine applications.

Язык: Английский

Two‐Photon Polymerization Lithography for Optics and Photonics: Fundamentals, Materials, Technologies, and Applications DOI Creative Commons
Hao Wang, Wang Zhang, Dimitra Ladika

и другие.

Advanced Functional Materials, Год журнала: 2023, Номер 33(39)

Опубликована: Март 22, 2023

Abstract The rapid development of additive manufacturing has fueled a revolution in various research fields and industrial applications. Among the myriad advanced 3D printing techniques, two‐photon polymerization lithography (TPL) uniquely offers significant advantage nanoscale print resolution, been widely employed diverse fields, for example, life sciences, materials mechanics, microfluidics. More recently, by virtue optical transparency most resins used, TPL is finding new applications optics photonics, with nanometer to millimeter feature dimensions. It enables minimization elements systems, exploration light‐matter interactions degrees freedom, never possible before. To review recent progress related research, it starts fundamentals material formulation, then discusses novel fabrication methods, wide range These notably include diffractive, topological, quantum, color optics. With panoramic view development, concluded insights perspectives future potential

Язык: Английский

Процитировано

174
High cell density and high-resolution 3D bioprinting for fabricating vascularized tissues DOI Creative Commons
Shangting You, Yi Xiang, Henry H. Hwang

и другие.

Science Advances, Год журнала: 2023, Номер 9(8)

Опубликована: Фев. 22, 2023

Three-dimensional (3D) bioprinting techniques have emerged as the most popular methods to fabricate 3D-engineered tissues; however, there are challenges in simultaneously satisfying requirements of high cell density (HCD), viability, and fine fabrication resolution. In particular, resolution digital light processing-based 3D suffers with increasing bioink due scattering. We developed a novel approach mitigate this scattering-induced deterioration The inclusion iodixanol enables 10-fold reduction scattering substantial improvement for bioinks an HCD. Fifty-micrometer was achieved 0.1 billion per milliliter density. To showcase potential application tissue/organ bioprinting, HCD thick tissues vascular networks were fabricated. viable perfusion culture system, endothelialization angiogenesis observed after 14 days culture.

Язык: Английский

Процитировано

118
Controlling Light in Scattering Materials for Volumetric Additive Manufacturing DOI
Jorge Madrid‐Wolff, Antoine Boniface, Damien Loterie

и другие.

Advanced Science, Год журнала: 2022, Номер 9(22)

Опубликована: Май 18, 2022

3D printing has revolutionized the manufacturing of volumetric components and structures in many areas. Several fully light-based techniques have been recently developed thanks to advent photocurable resins, promising reach unprecedented short print time (down a few tens seconds) while keeping good resolution (around 100 μm). However, these new approaches only work with homogeneous relatively transparent resins so that light patterns used for photo-polymerization are not scrambled along their propagation. Herein, method takes into account scattering resin prior computing projection is proposed. Using tomographic printer, it experimentally demonstrated implementation this correction critical when objects whose size exceeds mean free path. To show broad applicability technique, functional high fidelity fabricated hard organic acrylates soft cell-laden hydrogels (at 4 million cells mL-1 ). This opens up perspectives inside turbid materials particular interesting applications bioprinting constructs.

Язык: Английский

Процитировано

77
Light-based vat-polymerization bioprinting DOI
Riccardo Levato, Oksana Y. Dudaryeva, Carlos Ezio Garciamendez‐Mijares

и другие.

Nature Reviews Methods Primers, Год журнала: 2023, Номер 3(1)

Опубликована: Июнь 22, 2023

Язык: Английский

Процитировано

75
Progress of Microfluidic Hydrogel‐Based Scaffolds and Organ‐on‐Chips for the Cartilage Tissue Engineering DOI
Hamidreza Tolabi, Niyousha Davari, Mehran Khajehmohammadi

и другие.

Advanced Materials, Год журнала: 2023, Номер 35(26)

Опубликована: Янв. 12, 2023

Abstract Cartilage degeneration is among the fundamental reasons behind disability and pain across globe. Numerous approaches have been employed to treat cartilage diseases. Nevertheless, none shown acceptable outcomes in long run. In this regard, convergence of tissue engineering microfabrication principles can allow developing more advanced microfluidic technologies, thus offering attractive alternatives current treatments traditional constructs used applications. Herein, developments involving hydrogel‐based scaffolds, promising structures for regeneration, ranging from hydrogels with channels prepared by devices, that enable therapeutic delivery cells, drugs, growth factors, as well cartilage‐related organ‐on‐chips are reviewed. Thereafter, anatomy types damages, present treatment options briefly overviewed. Various introduced, advantages scaffolds over thoroughly discussed. Furthermore, available technologies fabricating chips presented. The preclinical clinical applications regeneration development time further explained. developments, recent key challenges, prospects should be considered so develop systems repair highlighted.

Язык: Английский

Процитировано

69
Compact holographic sound fields enable rapid one-step assembly of matter in 3D DOI Creative Commons
Kai Melde, Heiner Kremer, Minghui Shi

и другие.

Science Advances, Год журнала: 2023, Номер 9(6)

Опубликована: Фев. 8, 2023

Acoustic waves exert forces when they interact with matter. Shaping ultrasound fields precisely in 3D thus allows control over the force landscape and should permit particulates to fall into place potentially form whole objects "one shot." This is promising for rapid prototyping, most notably biofabrication, since conventional methods are typically slow apply mechanical or chemical stress on biological cells. Here, we realize generation of compact holographic demonstrate one-step assembly matter using acoustic forces. We combine multiple that drive contactless solid microparticles, hydrogel beads, cells inside standard labware. The structures can be fixed via gelation surrounding medium. In contrast previous work, this approach handles positive does not require opposing waves, supporting surfaces scaffolds. envision applications tissue engineering additive manufacturing.

Язык: Английский

Процитировано

62
Shaping Synthetic Multicellular and Complex Multimaterial Tissues via Embedded Extrusion‐Volumetric Printing of Microgels DOI Creative Commons

Davide Ribezzi,

Marième Gueye,

Sammy Florczak

и другие.

Advanced Materials, Год журнала: 2023, Номер 35(36)

Опубликована: Июнь 3, 2023

In living tissues, cells express their functions following complex signals from surrounding microenvironment. Capturing both hierarchical architectures at the micro- and macroscale, anisotropic cell patterning remains a major challenge in bioprinting, bottleneck toward creating physiologically-relevant models. Addressing this limitation, novel technique is introduced, termed Embedded Extrusion-Volumetric Printing (EmVP), converging extrusion-bioprinting layer-less, ultra-fast volumetric allowing spatially pattern multiple inks/cell types. Light-responsive microgels are developed for first time as bioresins (µResins) light-based providing microporous environment permissive homing self-organization. Tuning mechanical optical properties of gelatin-based microparticles enables use support bath suspended extrusion printing, which features containing high densities can be easily introduced. µResins sculpted within seconds with tomographic light projections into centimeter-scale, granular hydrogel-based, convoluted constructs. Interstitial microvoids enhanced differentiation stem/progenitor (vascular, mesenchymal, neural), otherwise not possible conventional bulk hydrogels. As proof-of-concept, EmVP applied to create synthetic biology-inspired intercellular communication models, where adipocyte regulated by optogenetic-engineered pancreatic cells. Overall, offers new avenues producing regenerative grafts biological functionality, developing engineered systems (metabolic) disease

Язык: Английский

Процитировано

52
The physics of 3D printing with light DOI
Paul Somers, Alexander Münchinger, Shoji Maruo

и другие.

Nature Reviews Physics, Год журнала: 2023, Номер 6(2), С. 99 - 113

Опубликована: Дек. 12, 2023

Язык: Английский

Процитировано

44
Advances in Microfluidics: Technical Innovations and Applications in Diagnostics and Therapeutics DOI
Guillaume Aubry, Hyun Jee Lee, Hang Lu

и другие.

Analytical Chemistry, Год журнала: 2023, Номер 95(1), С. 444 - 467

Опубликована: Янв. 10, 2023

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTAdvances in Microfluidics: Technical Innovations and Applications Diagnostics TherapeuticsGuillaume AubryGuillaume AubrySchool of Chemical & Biomolecular Engineering, Georgia Institute Technology, Atlanta, 30332, United StatesMore by Guillaume AubryView Biographyhttps://orcid.org/0000-0001-7828-8508, Hyun Jee LeeHyun LeeSchool LeeView Biographyhttps://orcid.org/0000-0001-9662-2063, Hang Lu*Hang LuSchool StatesPetit for Bioengineering Bioscience, States*Email: [email protected]More LuView Biographyhttps://orcid.org/0000-0002-6881-660XCite this: Anal. Chem. 2023, 95, 1, 444–467Publication Date (Web):January 10, 2023Publication History Published online10 January 2023Published inissue 10 2023https://pubs.acs.org/doi/10.1021/acs.analchem.2c04562https://doi.org/10.1021/acs.analchem.2c04562review-articleACS PublicationsCopyright © 2023 American SocietyRequest reuse permissionsArticle Views3385Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:3D printing,Biotechnology,Fluid dynamics,Liquids,Sensors Get e-Alerts

Язык: Английский

Процитировано

43
Volumetric additive manufacturing: A new frontier in layer-less 3D printing DOI Creative Commons
Daniel J. Whyte, Egan H. Doeven, Alessandra Sutti

и другие.

Additive manufacturing, Год журнала: 2024, Номер 84, С. 104094 - 104094

Опубликована: Март 1, 2024

Volumetric Additive Manufacturing (VAM) is an emerging 3D printing technology that operates by fabricating objects from all points within a medium's volume. This technique capable of producing parts without supporting structures and overprinting around existing structures. Notably, the approach VAM utilises to print time efficient compared traditional additive manufacturing methods with times being measured in seconds minutes instead hours. As this there little comparison or synthesis reported so far literature, thus primary objective review address issue providing comprehensive analysis VAM, delving into its applications, challenges it faces, research advancements made area. also investigates how new are investigated on, literature. In order achieve goal structured literature was conducted thoroughly examine current state VAM. found 30 papers, which were used categorise different methods, explore potential various fields, formulate definition for differentiate other technologies. A key finding while offers rapid fabrication capabilities, currently faces several constraints. These include limited availability commercial printers, complex methodologies, restricted range compatible materials, need specialised equipment. Collectively, these factors could serve as barriers broader adoption technology. addition, lack homogeneity parameters investigate report makes difficult compare contrast works against published field progresses, addressing will be essential unlock applications increase one first explicitly focus on entirety offering valuable insights present directions future research.

Язык: Английский

Процитировано

21