Label‐Free Metal‐Oxide Transistor Biosensors for Metabolite Detection in Human Saliva
Advanced Science,
Год журнала:
2024,
Номер
11(27)
Опубликована: Фев. 21, 2024
Metabolites
are
essential
molecules
involved
in
various
metabolic
processes,
and
their
deficiencies
excessive
concentrations
can
trigger
significant
physiological
consequences.
The
detection
of
multiple
metabolites
within
a
non-invasively
collected
biofluid
could
facilitate
early
prognosis
diagnosis
severe
diseases.
Here,
metal
oxide
heterojunction
transistor
(HJ-TFT)
sensor
is
developed
for
the
label-free,
rapid
uric
acid
(UA)
25(OH)Vitamin-D3
(Vit-D3)
human
saliva.
HJ-TFTs
utilize
solution-processed
In
Язык: Английский
Advances in Biosensor Applications of Metal/Metal-Oxide Nanoscale Materials
Chemosensors,
Год журнала:
2025,
Номер
13(2), С. 49 - 49
Опубликована: Фев. 3, 2025
Biosensing
shows
promise
in
detecting
cancer,
renal
disease,
and
other
illnesses.
Depending
on
their
transducing
processes,
varieties
of
biosensors
can
be
divided
into
electrochemical,
optical,
piezoelectric,
thermal
biosensors.
Advancements
material
production
techniques,
enzyme/protein
designing,
immobilization/conjugation
approaches
yield
novel
nanoparticles
with
further
developed
functionality.
Research
cutting-edge
biosensing
multifunctional
nanomaterials,
the
advancement
practical
biochip
plans
utilizing
nano-based
sensing
material,
are
current
interest.
The
miniaturization
electronic
devices
has
enabled
growth
ultracompact,
compassionate,
rapid,
low-cost
technologies.
Some
sensors
recognize
analytes
at
molecule,
particle,
single
biological
cell
levels.
Nanomaterial-based
sensors,
which
used
for
quickly
precisely,
replace
toxic
materials
real-time
diagnostics.
Many
metal-based
NPs
nanocomposites
favorable
biosensing.
Through
direct
indirect
labeling,
metal-oxide
extensively
employed
metabolic
disorders,
such
as
diabetes,
kidney-disease
biomarkers
based
magnetic
readouts.
present
review
focused
recent
developments
across
multiple
modalities
using
metal/metal-oxide-based
NPs;
particular,
we
highlighted
specific
advancements
key
nanomaterials
like
ZnO,
CeO2,
TiO2
applications
disease
diagnostics
environmental
monitoring.
For
example,
ZnO-based
uric
acid,
glucose,
cholesterol,
dopamine,
DNA;
is
utilized
SARS-CoV-19;
CeO2
glucose
detection.
Язык: Английский
A Rapid and Sensitive SERS-Based Au/MIL-125(Ti) Biosensor for Hyperuricemia Diagnosis via Saliva Analysis
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 19, 2025
An
Au/MIL-125(Ti)
nanocomposite
was
developed
as
a
novel
Raman-based
biosensor
platform
for
the
noninvasive
evaluation
of
uric
acid
(UA)
levels
in
saliva.
The
intensity
ratio
(I497/I1648)
Raman
spectrum
found
to
exhibit
quantitative
correlation
with
concentration
upon
its
adsorption
onto
MIL-125(Ti).
This
innovative
method
achieves
an
impressive
limit
detection
(LOD)
0.01
μM
consistent
performance
physiological
media.
shows
wide
linear
range
from
50
5000
μM,
showcasing
sensitivity
and
versatility.
Furthermore,
this
facilitates
rapid
UA
saliva
samples
can
distinguish
clearly
hyperuricemia
sufferers
healthy
controls
within
remarkable
time
frame
only
90
s
without
complicated
pretreatments,
highlighting
great
potential
real-time
diagnostics.
research
underscores
transformative
composite
biosensors
based
on
metal-organic
frameworks
(MOFs)
biomarker
sensing
applications,
paving
way
future
innovations
diagnostic
technologies.
Язык: Английский
Room-temperature phosphorescent carbonized polymer dots as superior photoresponsive oxidase mimics for colorimetric-fluorescence dual-mode enzyme-free sensing of uric acid
Biosensors and Bioelectronics,
Год журнала:
2025,
Номер
unknown, С. 117423 - 117423
Опубликована: Апрель 1, 2025
Язык: Английский
High-performance electrolyte-gated amorphous InGaZnO field-effect transistor for label-free DNA sensing
Bioelectrochemistry,
Год журнала:
2024,
Номер
160, С. 108794 - 108794
Опубликована: Авг. 10, 2024
Язык: Английский
Metal oxide thin film electronics
Applied Physics Letters,
Год журнала:
2024,
Номер
124(19)
Опубликована: Май 6, 2024
Metal
oxides,
once
a
scientific
curiosity,
1
have
evolved
into
transformative
technology
for
modern
electronics.
24][5][6][7]
The
ability
of
metal
oxides
to
deliver
semiconducting
channels
in
thin-film
transistors
(TFTs)
over
large-area
substrates
with
enhanced
performance
has
propelled
them
from
mere
curiosity
an
enabling
continuously
expanding
range
applications.The
flat
panel
display
industry
is
prime
example
the
pivotal
role
played
by
oxide
TFTs,
offering
numerous
attractive
attributes
absent
competing
technologies.
2,8,9
Recent
efforts
been
focused
on
new
and
dielectric
materials,
primary
goal
enhancing
device's
field-effect
mobility
operational
stability.However,
emergence
oxide-based
resistive
switching
devices
opened
up
exciting
avenues
research,
extending
application
space
memory
memristive
neuromorphic
computing
applications.
10,11etal
stand
out
field
thin
film
electronics
due
their
unique
physical
attributes.Their
optical
transparency,
ecofriendly
nature,
compatibility
energy-efficient
manufacturing
techniques
set
apart
other
technologies.These
characteristics
are
gaining
increasing
importance
light
harmful
environmental
effects
traditional
semiconductor
industry.To
this
end,
offer
potential
shift
toward
more
environmentally
responsible
products
that
can
help
reduce
society's
dependence
incumbent
technologies,
promising
revolutionize
our
fast-paced,
high-tech
world.This
special
topic
Applied
Physics
Letters
attempts
capture
latest
developments
materials
applications
broader
electronics.It
covers
research
exploration
functional
cutting-edge
techniques,
advanced
device
designs,
plethora
key
highlights
different
contributions
issue
organized
based
specific
area
research:
Язык: Английский
ZnO-based Thin Film Metal Oxide Semiconductors and Structures: Transistors, Optoelectronic Devices and Future Sustainable Electronics
ECS Journal of Solid State Science and Technology,
Год журнала:
2024,
Номер
14(1), С. 015001 - 015001
Опубликована: Дек. 27, 2024
Metal
oxide
thin
films
are
critically
important
materials
for
modern
technologies,
particularly
semiconductor
in
transistors
and
optoelectronic
applications.
Many
metal
attract
interest
their
electronic
bandgap,
charge
carrier
mobility,
optical
opacity,
luminescence,
low
cost,
relative
abundance,
environmentally-friendly
production.
Additionally,
these
properties
often
tuneable
via
particle
size,
film
density,
surface
morphology,
deposition,
growth
method,
hetero-interface
engineering
or
ion-doping.
The
n-type
semiconducting
zinc
(ZnO)
is
an
material,
possessing
a
variety
of
useful
including
intrinsically
wide
direct
high
electron
relatively
exciton
binding
energy,
transparency,
demonstrated
metal-ion
doping,
range
different
morphologies
deposition
methods,
electro/photoluminescence,
existing
green
synthesis
methods.
Here,
aspects
ZnO
some
related
compound
oxides
reviewed,
focusing
on
how
the
unique
make
them
suitable
applications
from
transistors,
mobility
interfaces,
transparent
conductive
oxides,
photoanodes
photodetectors,
chemical
sensors,
photocatalysts,
superlattice
electronics,
more.
methods
impact
functionality
will
be
discussed
alongside
role
sustainable
optoelectronics.
Язык: Английский