Bio-energy-powered microfluidic devices DOI Creative Commons

Y. K. Li,

C. J. Xu, Yifan Liao

и другие.

Biomicrofluidics, Год журнала: 2024, Номер 18(6)

Опубликована: Дек. 1, 2024

Bio-microfluidic technologies offer promising applications in diagnostics and therapy, yet they face significant technical challenges, particularly the need for external power sources, which limits their practicality user-friendliness. Recent advancements have explored innovative methods utilizing body fluids, motion, heat to these devices, addressing supply issue effectively. Among these, body-motion body-heat-powered systems stand out potential create self-sustaining, wearable, implantable devices. In this Perspective, we focus on principles of hydrovoltaic cells, biofuel piezoelectric triboelectric nanogenerators. strides energy conversion efficiency, coupled with development biocompatible durable materials, are driving innovation bio-integrated electronics. Integration bio-microfluidic platforms further enhances linkage human devices personalized healthcare applications. Ongoing research into areas promises deliver sustainable user-friendly solutions continuous monitoring, diagnostics, potentially revolutionizing landscape delivery.

Язык: Английский

Multi‐Zone Visco‐Node‐Pore Sensing: A Microfluidic Platform for Multi‐Frequency Viscoelastic Phenotyping of Single Cells DOI Creative Commons
Andre Lai, Stefan Hinz, Alan Dong

и другие.

Advanced Science, Год журнала: 2024, Номер 11(43)

Опубликована: Сен. 23, 2024

Abstract This study introduces multi‐zone visco‐Node‐Pore Sensing (mz‐visco‐NPS), an electronic‐based microfluidic platform for single‐cell viscoelastic phenotyping. mz‐visco‐NPS implements a series of sinusoidal‐shaped contraction zones that periodically deform cell at specific strain frequencies, leading to changes in resistance across the correspond cell's frequency‐dependent elastic G′ and viscous G″ moduli. is validated by measuring MCF‐7 cells when their cytoskeleton disrupted. also employed measure properties human mammary epithelial entire continuum transformation states, from average‐ high‐risk primary cells, immortal non‐malignant (MCF‐10A), malignant (MCF‐7), metastatic (MDA‐MB‐231) lines. With throughput 600 per hour demonstrated ease‐of‐use, reveals remarkable level heterogeneity would otherwise be masked ensemble averaging.

Язык: Английский

Процитировано

2
Bio-energy-powered microfluidic devices DOI Creative Commons

Y. K. Li,

C. J. Xu, Yifan Liao

и другие.

Biomicrofluidics, Год журнала: 2024, Номер 18(6)

Опубликована: Дек. 1, 2024

Bio-microfluidic technologies offer promising applications in diagnostics and therapy, yet they face significant technical challenges, particularly the need for external power sources, which limits their practicality user-friendliness. Recent advancements have explored innovative methods utilizing body fluids, motion, heat to these devices, addressing supply issue effectively. Among these, body-motion body-heat-powered systems stand out potential create self-sustaining, wearable, implantable devices. In this Perspective, we focus on principles of hydrovoltaic cells, biofuel piezoelectric triboelectric nanogenerators. strides energy conversion efficiency, coupled with development biocompatible durable materials, are driving innovation bio-integrated electronics. Integration bio-microfluidic platforms further enhances linkage human devices personalized healthcare applications. Ongoing research into areas promises deliver sustainable user-friendly solutions continuous monitoring, diagnostics, potentially revolutionizing landscape delivery.

Язык: Английский

Процитировано

0