Traditional Chinese medicine as a promising choice for future control of PEDV DOI Creative Commons

Cheng-ye Ji,

Shuxuan Li,

Christine Hu

и другие.

Virus Research, Год журнала: 2025, Номер unknown, С. 199572 - 199572

Опубликована: Апрель 1, 2025

Porcine epidemic diarrhea virus (PEDV) is the major agent of recent outbreaks in piglets, which has caused huge economic losses to global swine industry. Since traditional vaccine strategies cannot provide complete protection for development safe, effective, and economical antiviral drugs urgently needed. For many years, Chinese medicines (TCMs) have been broadly applied viral infectious diseases, exhibiting advantages such as abundant resources, lower toxicity, minimal drug resistance. Many herbal monomers, single extracts derived from these drugs, recipes exhibit significant anti-PEDV effects vitro and/or vivo by targeting multiple sites perspectives, including inhibition life cycle, anti-inflammation effects, enhancement host immune response, modulation reactive oxygen species, apoptosis. However, date, no review published on TCM. Therefore, this summarizes current control PEDV systematically analyses research progress TCMs against PEDV. Furthermore, future directions integration nanotechnology artificial intelligence with are also discussed. This will a valuable reference studies research.

Язык: Английский

Traditional Chinese medicine as a promising choice for future control of PEDV DOI Creative Commons

Cheng-ye Ji,

Shuxuan Li,

Christine Hu

и другие.

Virus Research, Год журнала: 2025, Номер unknown, С. 199572 - 199572

Опубликована: Апрель 1, 2025

Porcine epidemic diarrhea virus (PEDV) is the major agent of recent outbreaks in piglets, which has caused huge economic losses to global swine industry. Since traditional vaccine strategies cannot provide complete protection for development safe, effective, and economical antiviral drugs urgently needed. For many years, Chinese medicines (TCMs) have been broadly applied viral infectious diseases, exhibiting advantages such as abundant resources, lower toxicity, minimal drug resistance. Many herbal monomers, single extracts derived from these drugs, recipes exhibit significant anti-PEDV effects vitro and/or vivo by targeting multiple sites perspectives, including inhibition life cycle, anti-inflammation effects, enhancement host immune response, modulation reactive oxygen species, apoptosis. However, date, no review published on TCM. Therefore, this summarizes current control PEDV systematically analyses research progress TCMs against PEDV. Furthermore, future directions integration nanotechnology artificial intelligence with are also discussed. This will a valuable reference studies research.

Язык: Английский

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