Rapid purification and enrichment of viral particles using self-propelled micromotors DOI

Haipeng Cui,

Wenwei Pan,

Tiechuan Li

и другие.

Nanoscale, Год журнала: 2023, Номер 15(42), С. 17105 - 17112

Опубликована: Янв. 1, 2023

Schematic of the anti-SP-CSFA micromotors for virus enrichment.

Язык: Английский

Urease-Powered Micromotors with Spatially Selective Distribution of Enzymes for Capturing and Sensing Exosomes DOI
Xiaoxia Liu, Yong Wang, Yixin Peng

и другие.

ACS Nano, Год журнала: 2023, Номер 17(23), С. 24343 - 24354

Опубликована: Дек. 1, 2023

Enzyme-catalyzed micro/nanomotors (MNMs) exhibit tremendous potential for biological isolation and sensing, because of their biocompatibility, versatility, ready access to biofuel. However, flow field generated by enzyme-catalyzed reactions might significantly hinder performance surface-linked functional moieties, e.g., the binding interaction between MNMs target cargos. Herein, we develop enzymatic micromotors with spatially selective distribution urease enable independent operation various modules facilitate capture sensing exosomes. When is modified into motors' cavity, from enzyme catalysis has little effect on exterior surface motors. The active motion encapsulating internally result in enhancement ∼35% 18% efficiency cargos, exosomes as an example here, compared static counterparts moving externally, respectively. Once are trapped, they can be transferred a clean environment motors Raman signal detection and/or identification using scattering (SERS) coated gold nanoshell. biocatalytic micromotors, achieving spatial separation driving module function module, offer considerable promise future design multifunctional biomedicine diagnostics.

Язык: Английский

Процитировано

14

Self‐Degradable Photoactive Micromotors for Inactivation of Resistant Bacteria DOI Creative Commons
Xiaojiao Yuan, Salvio Suárez‐García, Marco De Corato

и другие.

Advanced Optical Materials, Год журнала: 2024, Номер 12(16)

Опубликована: Март 14, 2024

Abstract Pathogenic bacteria pose a significant threat to human health, and their removal from food water supplies is crucial in preventing the spread of waterborne foodborne diseases. Recently, silver‐based photocatalytic micromotors have emerged as promising candidates for inactivating pathogenic microbes due high antibacterial activity. In this study, synthesis photoactive Ag 3 PO 4 with well‐defined tetrapod‐like structure (TAMs) presented using simple precipitation method. These TAMs autonomously move release ions/nanoparticles (NPs) through photodegradation process when exposed light, which enhances antimicrobial activity against Gram‐negative ( Escherichia coli ) Gram‐positive Staphylococcus aureus bacterial strains. Interestingly, different motion modes are observed under manipulated light wavelengths fuels. Furthermore, self‐degradation accelerated presence negatively charged bacteria, results higher rates both E. Coli S. . The findings introduce new concept self‐degradable based on components, hold great potential use applications. This work offers implications materials chemistry, especially designing developing next generation light‐driven agents.

Язык: Английский

Процитировано

4

Succulent-like light-driven micromotor for dynamic fluorescence detection and photocatalytic degradation of tetracycline DOI Open Access
Fang Li, Xin-Yi Liu, Yuxin Gao

и другие.

Science China Materials, Год журнала: 2023, Номер 67(1), С. 179 - 187

Опубликована: Дек. 22, 2023

Язык: Английский

Процитировано

6

Nano/Micromotors for Cancer Diagnosis and Therapy: Innovative Designs to Improve Biocompatibility DOI Creative Commons

Jiahuan Zheng,

Rui Huang, Zhexuan Lin

и другие.

Pharmaceutics, Год журнала: 2023, Номер 16(1), С. 44 - 44

Опубликована: Дек. 27, 2023

Nano/micromotors are artificial robots at the nano/microscale that capable of transforming energy into mechanical movement. In cancer diagnosis or therapy, such “tiny robots” show great promise for targeted drug delivery, cell removal/killing, and even related biomarker sensing. Yet biocompatibility is still most critical challenge restricts techniques from transitioning laboratory to clinical applications. this review, we emphasize aspect nano/micromotors efforts made by researchers promote their application, mainly including non-toxic fuel propulsion (inorganic catalysts, enzyme, etc.), bio-hybrid designs, ultrasound propulsion, light-triggered magnetic dual and, in particular, cooperative swarm-based strategy increasing therapeutic effects. Future challenges translating real applications potential directions also described.

Язык: Английский

Процитировано

5

Scalable fabrication of biohybrid magnetic MOF-based micromotors for toxin enrichment DOI
Xiangyu Wang,

Haidong Yu,

Xiaohu Xia

и другие.

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 683, С. 27 - 38

Опубликована: Дек. 18, 2024

Язык: Английский

Процитировано

1

Light-driven Active Colloids DOI
Leilei Xu, Qiaoxin Guan, Jianguo Guan

и другие.

Royal Society of Chemistry eBooks, Год журнала: 2024, Номер unknown, С. 172 - 207

Опубликована: Дек. 20, 2024

Active colloids, capable of autonomous motion by harnessing energy available in their surroundings, are significance for advancing micro/nanoscale technologies. Light, as a ubiquitous external stimulus to propel the colloid particles, offers unique benefits such remote controllability, flexible tunability, and high temporal spatial resolution. Light-driven active colloids defined particles at that can swim under light irradiation. They, broadly speaking, include micro/nanomotors composed entirely or partially inorganic materials, microdroplets organic matters. propelled primarily relying on light-initiated transformations involving but not limited photochemical reaction, molecule isomerism, pressure temperature changes. In this chapter, we provide comprehensive overview various types associated with propulsion mechanisms related reactions, photoelectrochemical phenomena, photothermal effect, photoisomerisation, well optical momentum transfer. Then, relate them typical models light-driven colloidal systems. Furthermore, summarise uniqueness terms modulation, phototaxis, light-induced swarming, while highlighting important progress towards bionics, cargo capture transport, environmental remediation, biomedical engineering.

Язык: Английский

Процитировано

1

The Model Study of Phase-Transitional Magnetic-Driven Micromotors for Sealing Gastric Perforation via Mg-Based Micropower Traction DOI Creative Commons
Kang Xiong, Leilei Xu

Nanomaterials, Год журнала: 2024, Номер 14(10), С. 865 - 865

Опубликована: Май 16, 2024

Gastric perforation refers to the complete rupture of gastric wall, leading extravasation contents into thoracic cavity or peritoneum. Without timely intervention, expulsion may culminate in profound discomfort, exacerbating inflammatory process and potentially triggering perilous sepsis. In clinical practice, surgical suturing endoscopic closure procedures are commonly employed. Magnetic-driven microswarms have also been employed for sealing gastrointestinal perforation. However, intervention entails significant risk bleeding, while poses risks inadequate need subsequent removal clips. Moreover, efficacy is limited as they merely adhere perforated area, their effect diminishes upon magnetic field. Herein, we present a Fe&Mg@Lard-Paraffin micromotor (LPM) constructed from mixture lard paraffin coated with magnesium (Mg) microspheres iron (Fe) nanospheres sutureless perforations. Under control rotating field, this demonstrates precise over its movement on mucosal folds accurately targets area. The phase transition induced by high-frequency magnetothermal causes composed mixed oil change solid liquid phase. Mg subsequently exposed acidic acid environment produce protonation reaction, which turn generates hydrogen (H2) bubble recoil. Through Mg-based micropower traction, part could be pushed perforation, it would then solidify seal Experimental results show that can achieve long-term (>2 h) sealing. This innovative approach holds potential improving outcomes management.

Язык: Английский

Процитировано

0

Rapid purification and enrichment of viral particles using self-propelled micromotors DOI

Haipeng Cui,

Wenwei Pan,

Tiechuan Li

и другие.

Nanoscale, Год журнала: 2023, Номер 15(42), С. 17105 - 17112

Опубликована: Янв. 1, 2023

Schematic of the anti-SP-CSFA micromotors for virus enrichment.

Язык: Английский

Процитировано

0