Acceptorless dehydrogenation under neat reaction conditions: Synthesis of 2-aryl/alkyl quinazolinones using supported Ni NPs as catalyst
M. Vageesh,
Omkar Patil,
Raju Dey
и другие.
Synlett,
Год журнала:
2024,
Номер
35(20), С. 2496 - 2502
Опубликована: Авг. 15, 2024
Abstract
We
report
here
a
Ni-NPs-catalyzed
one-pot
synthesis
of
2-alkyl/aryl
quinazolinone
motifs
via
acceptorless
dehydrogenation
alcohol,
condensation
an
aldehyde
intermediate
with
2-aminobenzamide,
followed
by
second
the
cyclized
intermediate.
The
protocol
is
atom-economical
and
require
earth-abundant
Ni
as
catalyst.
present
involves
annulation
2-aminobenzamide
various
types
primary
alcohols,
including
aryl/heteroaryl
methanol,
aliphatic
produces
high
yields
desired
products
under
neat
conditions.
catalyst
was
synthesized
high-temperature
pyrolysis
strategy,
using
ZIF-8
sacrificial
template.
NPs@N-C
characterized
XPS,
HR-TEM,
HAADF-STEM,
XRD,
ICP-MS.
stable
even
in
air
at
room
temperature
displayed
excellent
activity
dehydrogenative
coupling
quinazolinones
could
be
recycled
five
times
without
appreciable
loss
its
activity.
Язык: Английский
Supported Nickel Nanoparticles as Catalyst in Direct sp3 C–H Alkylation of 9H‐Fluorene Using Alcohols as Alkylating Agent
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 14, 2024
Abstract
Herein,
we
report
an
inexpensive
first‐row
transition
metal
Ni
heterogeneous
catalytic
system
for
the
C
sp
3
‐mono
alkylation
of
fluorene
using
alcohols
as
alkylating
agents
via
borrowing
hydrogen
strategy.
The
protocol
displayed
versatility
with
high
yields
desired
products
various
types
primary
alcohols,
including
aryl/hetero
aryl
methanols,
and
aliphatic
agents.
catalyst
NPs@N−C
was
synthesized
high‐temperature
pyrolysis
strategy,
ZIF‐8
sacrificial
template.
characterized
by
XPS,
HR‐TEM,
HAADF‐STEM,
XRD
ICP‐MS.
is
stable
even
in
air
at
room
temperature,
excellent
activity
could
be
recycled
5
times
without
appreciable
loss
its
activity.
Язык: Английский