Metal‐Protein Hybrid Materials: Unlocking New Frontiers in Biomedical Applications
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 7, 2025
Abstract
Metal‐protein
hybrid
materials
represent
a
novel
class
of
functional
that
exhibit
exceptional
physicochemical
properties
and
tunable
structures,
rendering
them
remarkable
applications
in
diverse
fields,
including
engineering,
biocatalysis,
biosensing,
biomedicine.
The
design
development
multifunctional
biocompatible
metal‐protein
have
been
the
subject
extensive
research
key
aspiration
for
practical
clinical
settings.
This
review
provides
comprehensive
analysis
strategies,
intrinsic
properties,
biomedical
these
materials,
with
specific
emphasis
on
their
potential
cancer
therapy,
drug
vaccine
delivery,
antibacterial
treatments,
tissue
regeneration.
Through
rational
design,
stable
can
be
synthesized
using
straightforward
methods,
enabling
therapeutic,
immunomodulatory,
other
desired
functionalities.
Finally,
outlines
existing
limitations
challenges
associated
evaluates
translation,
providing
insights
into
implementation
within
applications.
Язык: Английский
Synthesis of Hybrid ZnO Nanohexagons and Nanorods with CNT Embedded in PVC Film for Advanced Insulation and Optoelectronic Applications
ECS Journal of Solid State Science and Technology,
Год журнала:
2025,
Номер
14(3), С. 031004 - 031004
Опубликована: Фев. 24, 2025
This
study
focuses
on
the
synthesis,
characterization,
and
application
of
a
novel
polyvinyl
chloride
(PVC)/carbon
nanotube
(CNT)/zinc
oxide
(ZnO)
hybrid
nanocomposite.
ZnO
nanostructures
with
two
distinct
morphologies
(nanohexagons
nanorods)
were
synthesized
embedded
within
PVC
matrix
alongside
CNTs
to
achieve
functional
composite.
TEM
analysis
revealed
presence
both
nanohexagon
nanorod
structures
CNTs.
SEM
EDX
analyses
confirmed
uniform
distribution
matrix.
FTIR
UV–vis
successful
integration
ZnO,
exhibiting
well-defined
high
aspect
ratio.
The
optical
properties
are
characterized
by
reduction
in
bandgap
from
5.40
eV
for
PVC/ZnO
4.60
PVC/ZnO/5%CNT,
indicating
an
increase
absorption
visible
spectrum.
Furthermore,
AC
conductivity
demonstrates
significant
frequency
dependence,
increasing
CNT
concentration
due
formation
conductive
pathways.
dielectric
constant
also
shows
enhanced
values
increased
content,
attributed
improved
interfacial
polarization.
simulation
electric
field
reveals
that
PVC/CNT/ZnO
nanocomposite
exhibits
more
than
conventional
PVC.
concludes
has
potential
applications
optoelectronics
devices.
Язык: Английский
Prussian blue nanohybrid hydrogel combined with specific far-infrared based on graphene devices for promoting diabetic wound healing
Materials & Design,
Год журнала:
2025,
Номер
unknown, С. 113839 - 113839
Опубликована: Март 1, 2025
Язык: Английский
Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism
Nanomedicine Nanotechnology Biology and Medicine,
Год журнала:
2025,
Номер
unknown, С. 102820 - 102820
Опубликована: Апрель 1, 2025
Язык: Английский
Biomedical Potential of Cellulose: Current Trends and Future Directions
Polymers for Advanced Technologies,
Год журнала:
2024,
Номер
35(12)
Опубликована: Ноя. 25, 2024
ABSTRACT
The
exploration
of
cellulose,
a
natural
polysaccharide
derived
from
renewable
biomass,
has
seen
significant
advancements
in
recent
years
due
to
its
biocompatibility,
biodegradability,
and
versatility.
This
review
paper
comprehensively
covers
the
latest
developments
cellulose
derivatives
as
functional
biomaterials
for
various
biomedical
applications.
Emphasis
is
placed
on
intrinsic
properties
such
mechanical
strength,
thermal
stability,
chemical
modifiability,
which
enable
wide‐ranging
use
drug
delivery
systems,
wound
dressings,
tissue
engineering,
biosensors.
article
further
delves
into
modification
techniques—such
oxidation,
esterification,
etherification—that
enhance
cellulose's
performance,
allowing
it
be
fine‐tuned
specialized
medical
applications,
including
creation
scaffolds
regeneration
smart
materials
responsive
release.
Additionally,
hybridization
with
inorganic
offers
potential
developing
superior
antimicrobial
improved
characteristics.
also
addresses
challenges
processing,
particularly
concerning
optimizing
structure
specific
while
highlighting
future
opportunities
field
personalized
medicine
intelligent
healthcare
devices.
By
examining
both
current
innovations
trends,
this
highlights
growing
importance
sustainable
versatile
resource
industry.
Язык: Английский
Reliable Fabrication of Mineral‐Graded Scaffolds by Spin‐Coating and Laser Machining for Use in Tendon‐to‐Bone Insertion Repair
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 5, 2024
A
reliable
method
for
fabricating
biomimetic
scaffolds
with
a
controllable
mineral
gradient
to
facilitate
the
surgical
repair
of
tendon-to-bone
injuries
and
regeneration
enthesis
is
reported.
The
in
content
created
by
sequentially
spin-coating
hydroxyapatite/poly(ε-caprolactone)
suspensions
containing
hydroxyapatite
nanoparticles
decreasing
concentrations.
To
produce
pores
cell
infiltration,
spin-coated
film
released
patterned
an
array
funnel-shaped
microchannels
laser
machining.
unique
design
provided
both
mechanical
(i.e.,
substrate
stiffness)
biochemical
(e.g.,
content)
cues
spatially
control
graded
differentiation
mesenchymal
stem
cells.
Immunocytochemical
analysis
human
cell-seeded
after
14
days
culture
demonstrated
formation
spatial
phenotypic
from
osteoblasts
mineralized
chondrocytes
based
on
level
mineralization
scaffold.
By
successfully
recreating
compositional
cellular
features
native
tendon
enthesis,
offer
promising
avenue
improved
repair.
Язык: Английский
Bioengineering nanomaterials for tumor therapy and anti-metastasis
Progress in Materials Science,
Год журнала:
2024,
Номер
unknown, С. 101375 - 101375
Опубликована: Сен. 1, 2024
Язык: Английский
Advanced Nanomaterials in Imaging and Diagnostics
Advances in chemical and materials engineering book series,
Год журнала:
2024,
Номер
unknown, С. 79 - 100
Опубликована: Окт. 22, 2024
The
science
of
imaging
and
diagnostics
has
been
completely
transformed
by
nanotechnology
biomedicine,
which
created
previously
unheard-of
prospects
for
early
illness
diagnosis,
precision
monitoring,
tailored
medication.
astounding
advancements
in
sophisticated
nanomaterials
have
the
potential
to
revolutionize
healthcare
offering
cutting-edge
approaches
diagnosis
individualized
treatment.
Nanomaterials
special
qualities
that
make
them
excellent
choices
biological
applications.
These
include
optical,
magnetic,
structural
adjustable
features.
Targeting
ligands,
stimuli-responsive
elements,
agents
increase
specificity
sensitivity,
making
identifying
diseases
tracking
treatment
outcomes
easier.
many
kinds
utilized
were
discussed,
including
metal
nanoparticles,
carbon-based
nanomaterials,
lipid-based
quantum
dots.
Язык: Английский
Editorial: Exploring the potential of nanobiomaterials in biomedical engineering: assessing biocompatibility, toxicity, and future prospects
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Окт. 23, 2024
The
future
of
NBMs
holds
immense
promise.
By
leveraging
the
capabilities
nanotechnology
and
emulating
intricate
structures
living
tissues,
offer
exciting
possibilities
for
diverse
biomedical
applications
(Figure
1).
These
include
targeted
drug
delivery
systems
to
advanced
implants
improve
human
health.
However,
this
progress
hinges
on
a
commitment
rigorous
safety
assessments
deep
understanding
how
interact
with
biological
systems.
Through
ongoing
research
development,
can
transform
we
diagnose,
treat,
prevent
diseases,
heralding
new
era
personalized
medicine.
This
special
issue
explores
vital
interactions
between
cells/tissues,
focusing
factors
such
as
size,
morphology,
shape,
surface
chemistry
NBM
influence
toxicity,
biocompatibility,
immunogenicity.
elucidating
these
structure-function
relationships,
aim
facilitate
creation
innovative
tailored
properties
applications.
includes
three
papers
two
review
articles
exploring
recent
advances
in
design,
preparation,
biocompatibility
assessment
NBMs.Guedri
et
al.
investigated
potential
using
alumina-ferrite
(Al2O3-Fe3O4)
hybrid
nanoparticles
thermal
various
fields,
including
biomedicine,
electronics,
mechanical
engineering.
11
Their
study
focused
interaction
blood
over
3D
surface,
considering
like
nonlinear
radiation,
stretching,
velocity
slippage,
magnetic
field.
A
mathematical
model
was
developed
nanofluid
similarity
rules.
Numerical
simulations
were
performed
analyze
behavior
within
blood.
results
showed
that
strong
field
effectively
controlled
motion
nanoparticles,
while
stretching
increased
fluid
movement.
Thermal
radiation
found
enhance
both
Al2O3-Fe3O4/blood
Al2O3/blood.
In
iron
sulfide-based
nanozymes
(ISNs),
Shan
highlighted
growing
interest
due
their
stability,
ease
tunability.
12
They
ISNs,
widely
studied
nanomaterial
enzyme-mimicking
properties,
outlining
classification
catalytic
mechanisms
followed
by
detailed
examination
use
biosensors,
tumor
therapy,
antibacterial
other
areas,
underlining
promise
improving
health.In
another
study,
Puri
explored
green
synthesis
selenium
(SeNPs)
Terminalia
arjuna
bark
extract.
13
abundant
phenolics,
flavonoids,
tannins
extract
acted
capping
stabilizing
agents,
enabling
formation
stable,
negatively
charged,
spherical
TA-SeNPs.
biogenic
SeNPs
exhibited
excellent
antioxidant,
antibacterial,
anticancer
activities,
making
them
promising
candidates
Notably,
TA-SeNP-incorporated
gel
displayed
desirable
topical
use.
highlights
safe
sustainable
development
nanomedicines.Roma
reviewed
advancements
graphene
its
derivatives
dental
14
Highlighting
unique
activity,
authors
discuss
methods,
material
characteristics,
uses
graphene-based
materials.
concludes
challenges
nanomaterials
dentistry,
aiming
stimulate
further
research.A
Dar
effects
nutrient
sources
rice
growth
yield.
15
Eight
practices
evaluated,
recommended
fertilizer
dose
(RFD),
RFD
silicon
supplement,
organic
manure
(FYM).
treatment
basal
application
Vigore
(a
commercial
product)
spray
at
panicle
initiation
(PI)
stage
(N3)
resulted
highest
plant
height,
number
tillers,
density,
weight,
grain
approach
yielded
22-25%
more
than
FYM
or
alone.
suggests
timing
significantly
yield.Altogether,
presented
highlight
significant
nanobiomaterials.
We
extend
our
sincere
gratitude
all
contributing
sharing
valuable
insights
solutions.
Special
thanks
go
editors
reviewers
whose
expertise
enhanced
quality
papers.
Despite
advancements,
remain.
Future
success
deeper
Continued
hold
revolutionize
disease
diagnosis,
treatment,
prevention,
paving
way
trust
will
be
informative
inspiring,
particularly
young
scholars
eager
contribute
research.
Язык: Английский