Organic Letters, Год журнала: 2024, Номер 26(46), С. 9978 - 9983

Опубликована: Ноя. 11, 2024

A generality-oriented and adaptive α-sulfonylation of alkynes via photoinduced multicomponent radical cross-coupling terminal with sulfinates a variety alcohols, thiophenols, or selenophenols has been explored. This protocol features mild conditions, good functional group tolerability, broad substrate scope, excellent chemo-, site-, stereoselectivity, applicability to late-stage functionalization. It provides modular platform for the synthesis value-added structurally diverse α-sulfonyl-containing multisubstituted alkenes from simple precursors.

Язык: Английский