Advanced Synthesis & Catalysis,
Год журнала:
2017,
Номер
359(24), С. 4300 - 4304
Опубликована: Окт. 3, 2017
Abstract
A
Bronsted
acid
promoted
three‐component
synthesis
of
substituted
thieno[2,3‐
b
]indole
has
been
developed
starting
from
indoles,
alkenes
or
alkynes,
and
sulfur
powder.
N
,
‐Dimethylformamide
plays
an
important
role
to
convert
the
materials
into
fused
products.
Various
functional
groups
attached
substrates
were
well
tolerated
afford
corresponding
products
in
moderate
good
yields
under
very
simple
reaction
conditions.
magnified
image
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(12), С. 8632 - 8640
Опубликована: Июнь 6, 2024
Herein,
we
disclosed
a
highly
efficient
pathway
toward
3-selenylated
chromone
derivatives
via
electrocatalytic
cascade
selenylation/cyclization/deamination
of
2-hydroxyaryl
enaminones
with
diselenides.
This
method
showed
mild
conditions,
easy
operation,
wide
substrate
scope,
and
good
functional
group
tolerance.
Furthermore,
this
electrosynthesis
strategy
was
amendable
to
scale-up
the
reaction.
Additionally,
preliminary
experiments
revealed
that
reaction
probably
proceeded
cation
instead
radical
pathway.
Organic Letters,
Год журнала:
2017,
Номер
19(2), С. 408 - 411
Опубликована: Янв. 4, 2017
An
I2-promoted
domino
bicyclization
approach
via
multiple
sequential
C-H
functionalization
was
serendipitously
discovered
for
the
synthesis
of
1,2-fused
oxindoles
from
methyl
ketones
and
anilines.
This
optimized,
resulting
in
a
concise
atom-economical
one-pot
construction
anilines
rather
than
using
preexisting
indolin-3-ones
or
indoles.
Mechanistic
studies
revealed
that
key
step
involved
an
oxidative
cross-coupling
between
situ
generated
phenylglyoxal
α,α-diaminoketone.
Advanced Synthesis & Catalysis,
Год журнала:
2017,
Номер
359(24), С. 4300 - 4304
Опубликована: Окт. 3, 2017
Abstract
A
Bronsted
acid
promoted
three‐component
synthesis
of
substituted
thieno[2,3‐
b
]indole
has
been
developed
starting
from
indoles,
alkenes
or
alkynes,
and
sulfur
powder.
N
,
‐Dimethylformamide
plays
an
important
role
to
convert
the
materials
into
fused
products.
Various
functional
groups
attached
substrates
were
well
tolerated
afford
corresponding
products
in
moderate
good
yields
under
very
simple
reaction
conditions.
magnified
image
