Chemical Reviews,
Год журнала:
2018,
Номер
119(4), С. 2192 - 2452
Опубликована: Ноя. 27, 2018
C–H
activation
has
surfaced
as
an
increasingly
powerful
tool
for
molecular
sciences,
with
notable
applications
to
material
crop
protection,
drug
discovery,
and
pharmaceutical
industries,
among
others.
Despite
major
advances,
the
vast
majority
of
these
functionalizations
required
precious
4d
or
5d
transition
metal
catalysts.
Given
cost-effective
sustainable
nature
earth-abundant
first
row
metals,
development
less
toxic,
inexpensive
3d
catalysts
gained
considerable
recent
momentum
a
significantly
more
environmentally-benign
economically-attractive
alternative.
Herein,
we
provide
comprehensive
overview
on
until
summer
2018.
Chemical Society Reviews,
Год журнала:
2018,
Номер
47(17), С. 6603 - 6743
Опубликована: Янв. 1, 2018
The
present
review
is
devoted
to
summarizing
the
recent
advances
(2015-2017)
in
field
of
metal-catalysed
group-directed
C-H
functionalisation.
In
order
clearly
showcase
molecular
diversity
that
can
now
be
accessed
by
means
directed
functionalisation,
whole
organized
following
directing
groups
installed
on
a
substrate.
Its
aim
comprehensive
reference
work,
where
specific
group
easily
found,
together
with
transformations
which
have
been
carried
out
it.
Hence,
primary
format
this
schemes
accompanied
concise
explanatory
text,
are
ordered
sections
according
their
chemical
structure.
feature
typical
substrates
used,
products
obtained
as
well
required
reaction
conditions.
Importantly,
each
example
commented
respect
most
important
positive
features
and
drawbacks,
aspects
such
selectivity,
substrate
scope,
conditions,
removal,
greenness.
targeted
readership
both
experts
functionalisation
chemistry
(to
provide
overview
progress
made
last
years)
and,
even
more
so,
all
organic
chemists
who
want
introduce
way
thinking
for
design
straightforward,
efficient
step-economic
synthetic
routes
towards
molecules
interest
them.
Accordingly,
should
particular
also
scientists
from
industrial
R&D
sector.
overall
goal
promote
application
reactions
outside
research
dedicated
method
development
establishing
it
valuable
archetype
contemporary
R&D,
comparable
role
cross-coupling
play
date.
Chemical Reviews,
Год журнала:
2016,
Номер
117(13), С. 9163 - 9227
Опубликована: Дек. 12, 2016
The
transition-metal-catalyzed
addition
of
C–H
bonds
to
carbonyls,
imines,
and
related
polarized
π
has
emerged
as
a
particularly
efficient
powerful
approach
for
the
construction
an
incredibly
diverse
array
heteroatom-substituted
products.
Readily
available
stable
inputs
are
typically
employed,
reactions
often
proceed
with
very
high
functional
group
compatibility
without
production
waste
byproducts.
Additionally,
many
bond
additions
occur
within
cascade
reaction
sequences
provide
rapid
access
different
heterocyclic
well
carbocyclic
This
review
highlights
diversity
transformations
that
have
been
achieved,
catalysts
used,
types
products
prepared
through
bonds.
Advanced Synthesis & Catalysis,
Год журнала:
2017,
Номер
359(8), С. 1245 - 1262
Опубликована: Март 16, 2017
Abstract
High‐valent
(pentamethylcyclopentadienyl)cobalt(III)
[Cp*Co(III)]
catalysts
were
found
as
inexpensive
alternatives
to
(pentamethylcyclopentadienyl)rhodium(III)
[Cp*Rh(III)]
in
the
field
of
C—H
bond
functionalization,
and
applied
a
variety
transformations.
In
this
review,
after
discovery
early
examples
Cp*Co(III)‐catalyzed
functionalization
are
summarized,
unique
reactivity
selectivity
Cp*Co(III)
differences
between
cobalt
rhodium
catalysis
intensively
discussed.
Such
assumed
be
caused
by
lower
electronegativity,
hard
nature,
smaller
ionic
radius
cobalt.
magnified
image
Chemical Communications,
Год журнала:
2017,
Номер
53(22), С. 3165 - 3180
Опубликована: Янв. 1, 2017
Significant
progress
has
been
accomplished
in
directed
C–H
functionalization
through
the
use
of
earth-abundant
and
inexpensive
first-row
transition
metals.
Angewandte Chemie International Edition,
Год журнала:
2018,
Номер
57(47), С. 15425 - 15429
Опубликована: Окт. 6, 2018
The
enantioselective
cobalt(III)-catalyzed
C-H
alkylation
was
achieved
through
the
design
of
a
novel
chiral
acid.
activation
characterized
by
high
position-,
regio-
and
enantio-control
under
exceedingly
mild
reaction
conditions.
Thereby,
robust
cooperative
cobalt(III)
catalysis
proved
tolerant
valuable
electrophilic
functional
groups,
including
hydroxyl,
bromo,
iodo
substituents.
Mechanistic
studies
revealed
considerable
additive
effect
on
kinetics
negative
non-linear-effect.
Angewandte Chemie International Edition,
Год журнала:
2016,
Номер
55(48), С. 15166 - 15170
Опубликована: Окт. 27, 2016
Abstract
Herein,
we
report
an
unprecedented
regioselective
and
entirely
atom‐economic
cobalt(III)‐catalyzed
method
for
the
non‐annulative,
intermolecular
carboamination
of
alkenes.
The
methodology
enables
direct
synthesis
unnatural
amino
acid
derivatives
proceeds
under
redox‐neutral
conditions
with
a
completely
C−C
bond
C−N
formation.
Furthermore,
this
reaction
exemplifies
inherently
different
mechanistic
behavior
Cp*Co
III
catalyst
its
Cp*Rh
counterpart,
especially
towards
β‐H‐elimination.
Chemical Reviews,
Год журнала:
2022,
Номер
122(24), С. 17479 - 17646
Опубликована: Окт. 14, 2022
Alkenes
and
their
derivatives
are
featured
widely
in
a
variety
of
natural
products,
pharmaceuticals,
advanced
materials.
Significant
efforts
have
been
made
toward
the
development
new
practical
methods
to
access
this
important
class
compounds
by
selectively
activating
alkenyl
C(sp2)–H
bonds
recent
years.
In
comprehensive
review,
we
describe
state-of-the-art
strategies
for
direct
functionalization
sp2
C–H
C–F
until
June
2022.
Moreover,
metal-free,
photoredox,
electrochemical
also
covered.
For
clarity,
review
has
divided
into
two
parts;
first
part
focuses
on
currently
available
using
different
alkene
as
starting
materials,
second
describes
bond
easily
accessible
gem-difluoroalkenes
material.
This
includes
scope,
limitations,
mechanistic
studies,
stereoselective
control
(using
directing
groups
well
metal-migration
strategies),
applications
complex
molecule
synthesis
where
appropriate.
Overall,
aims
document
considerable
advancements,
current
status,
emerging
work
critically
summarizing
contributions
researchers
working
fascinating
area
is
expected
stimulate
novel,
innovative,
broadly
applicable
functionalizations
coming
Chemical Society Reviews,
Год журнала:
2021,
Номер
50(5), С. 3263 - 3314
Опубликована: Янв. 1, 2021
Olefinic
C-H
functionalization
represents
an
atom-
and
step
economic
approach
to
valuable
olefin
derivatives
from
simpler
ones,
but
controlling
the
selectivity
remains
a
challenge.
Remarkable
progress
has
been
made
in
site-selective
of
arenes
alkanes,
there
are
still
limited
examples
selective
olefins
presumably
due
lability
easy
decomposition
alkenyl
moiety.
Chelation-assisted
activation
efficient
protocol
for
site-
stereo-selective
construction
carbon-carbon
carbon-heteroatom
bonds.
This
review
highlights
recent
advances
vicinal-
geminal-group-directed
olefinic
functionalization,
including
alkenylation,
arylation,
alkynylation,
alkylation,
halogenation,
silylation,
cyanation
annulation
by
formation
exo-/endo-metallocycles.
In
particular,
is
covered
first
time,
as
well
distal-selective
under
palladium/norbornene
cooperative
catalysis,
which
provides
novel
disconnections
retrosynthetic
analysis
future
trend
green
chemistry.
