Organic Letters,
Год журнала:
2020,
Номер
22(10), С. 3974 - 3978
Опубликована: Май 4, 2020
A
highly
chemoselective
base-metal
catalyzed
hydrogenation
and
acceptorless
dehydrogenation
of
N-heterocycles
is
presented.
well-defined
Mn
complex
operates
at
low
catalyst
loading
(as
as
2
mol
%)
under
mild
reaction
conditions.
The
described
catalytic
system
tolerates
various
functional
groups,
the
corresponding
reduced
heterocycles
can
be
obtained
in
high
yields.
Experimental
studies
indicate
a
metal-ligand
cooperative
catalysis
mechanism.
Angewandte Chemie International Edition,
Год журнала:
2021,
Номер
60(29), С. 16035 - 16043
Опубликована: Апрель 24, 2021
Reductive
transformations
of
easily
available
oxidized
matter
are
at
the
heart
synthetic
manipulation
and
chemical
valorization.
The
applications
catalytic
hydrofunctionalization
benefit
from
use
liquid
reducing
agents
operationally
facile
setups.
Metal-catalyzed
hydroborations
provide
a
highly
prolific
platform
for
reductive
valorizations
stable
C=X
electrophiles.
Here,
we
report
an
especially
facile,
broad-scope
reduction
various
functions
including
carbonyls,
carboxylates,
pyridines,
carbodiimides,
carbonates
under
very
mild
conditions
with
inexpensive
pre-catalyst
Mn(hmds)2
.
reaction
could
be
successfully
applied
to
depolymerizations.
Organic Letters,
Год журнала:
2020,
Номер
22(10), С. 3974 - 3978
Опубликована: Май 4, 2020
A
highly
chemoselective
base-metal
catalyzed
hydrogenation
and
acceptorless
dehydrogenation
of
N-heterocycles
is
presented.
well-defined
Mn
complex
operates
at
low
catalyst
loading
(as
as
2
mol
%)
under
mild
reaction
conditions.
The
described
catalytic
system
tolerates
various
functional
groups,
the
corresponding
reduced
heterocycles
can
be
obtained
in
high
yields.
Experimental
studies
indicate
a
metal-ligand
cooperative
catalysis
mechanism.
