Recent Progress in Electrochemiluminescence Sensing and Imaging

Analytical Chemistry, Год журнала: 2019, Номер 92(1), С. 431 - 454

Опубликована: Ноя. 4, 2019

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRecent Progress in Electrochemiluminescence Sensing and ImagingCheng MaCheng MaState Key Laboratory of Analytical Chemistry for Life Science, School Chemical Engineering, Nanjing University, 210023, P. R. ChinaMore by Cheng MaView Biographyhttp://orcid.org/0000-0001-5729-8483, Yue CaoYue CaoState CaoView Biographyhttp://orcid.org/0000-0002-8934-7195, Xiaodan GouXiaodan GouState GouView Biography, Jun-Jie Zhu*Jun-Jie ZhuState China*E-mail: [email protected]More ZhuView Biographyhttp://orcid.org/0000-0002-8201-1285Cite this: Anal. Chem. 2020, 92, 1, 431–454Publication Date (Web):November 3, 2019Publication History Published online4 November 2019Published inissue 7 January 2020https://pubs.acs.org/doi/10.1021/acs.analchem.9b04947https://doi.org/10.1021/acs.analchem.9b04947review-articleACS PublicationsCopyright © 2019 American SocietyRequest reuse permissionsArticle Views11665Altmetric-Citations354LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Electrodes,Genetics,Metal organic frameworks,Quantum dots,Sensors Get e-Alerts

Язык: Английский

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Recent Progress in the Development of Solid‐State Luminescent o‐Carboranes with Stimuli Responsivity

Angewandte Chemie International Edition, Год журнала: 2020, Номер 59(25), С. 9841 - 9855

Опубликована: Фев. 3, 2020

Abstract o ‐Carborane, a cluster compound containing boron and adjacent carbon atoms, displays intriguing luminescent properties. Recently, compounds ‐carborane units were found to show suppressed aggregation‐induced quenching intense solid‐state emission; they also potential for the development of stimuli‐responsive luminochromic materials. In this Minireview, we introduce three kinds fundamental photochemical properties: emission, twisted intramolecular charge transfer in crystals, environment‐sensitive excimer formation solids. Based on these properties, several types luminochromism, such as thermos‐, vapo‐, mechanochromism, have been discovered. mainly results from recent studies, illustrate mechanisms well unique behaviors derivatives.

Язык: Английский

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Dual Enhancement of Gold Nanocluster Electrochemiluminescence: Electrocatalytic Excitation and Aggregation‐Induced Emission

Angewandte Chemie International Edition, Год журнала: 2019, Номер 59(25), С. 9982 - 9985

Опубликована: Ноя. 6, 2019

Abstract Ligand‐protected gold nanoclusters (AuNCs) have emerged as a new class of electrochemiluminescence (ECL) luminophores for their interesting catalytic and emission properties, although quantum yield ( Φ ECL ) in aqueous medium is low with poor mechanistic understanding the process. Now it shown that drying AuNCs on electrodes enabled both enhanced electrochemical excitation by an electrocatalytic effect, aggregation‐induced (AIECL) 6‐aza‐2‐thiothymine (ATT) protected triethylamine (TEA) coreactant. The dried ATT‐AuNCs/TEA system resulted highly stable visual 78 %, similar enhancement was also achieved methionine‐capped AuNCs. dual‐enhancement mechanism has solved challenging problem AuNC probes, can guide further rational design emitters.

Язык: Английский

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Ultrafast Condensation of Carbon Nitride on Electrodes with Exceptional Boosted Photocurrent and Electrochemiluminescence

Angewandte Chemie International Edition, Год журнала: 2019, Номер 59(3), С. 1139 - 1143

Опубликована: Окт. 28, 2019

Semiconducting polymeric carbon nitride (CN) has drawn wide attention ranging from photocatalysis to more recent biosensing owing unique defect-tolerated optoelectronic properties and being metal-free, cheap, highly stable. However, at the core of electrical-optical interconversion, preparation CN photoelectrode is still challenging. Now, growth on electrodes achieved simply by microwave-assisted condensation in seconds. The ultrafast heating not only addressed thermodynamic contradiction precursor volatilization during polymerization but also led strongly adhesive layer with gradient carbon-rich texture, greatly accelerating electron-hole separation mobility. Consequently, exhibited a remarkable photocurrent record cathodic efficiency electrochemiluminescence up 7 times that benchmark Ru(bpy)3 Cl2 aqueous solution.

Язык: Английский

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Pre‐oxidation of Gold Nanoclusters Results in a 66 % Anodic Electrochemiluminescence Yield and Drives Mechanistic Insights

Angewandte Chemie International Edition, Год журнала: 2019, Номер 58(34), С. 11691 - 11694

Опубликована: Июнь 27, 2019

Gold nanoclusters (AuNCs) are attractive electrochemiluminescence (ECL) emitters because of their excellent stability, near IR emission, and biocompatibility. However, ECL quantum yield is relatively low, our limited fundamental understanding has hindered rational improvement this parameter. Herein, we report drastic enhancement the ligand-stabilized AuNCs by on-electrode pre-oxidation with triethylamine (TEA) as a co-reactant. The l-methionine-stabilized resulted in record high 66 %. This strategy was successfully extended to other AuNCs, it more effective for ligand shells that allow electron transfer. In addition, excitation pre-oxidized required lower potential than conventional methods, no additional instrument required. work opens avenues solving challenging problem AuNC-based probes enriches understanding, greatly broadening applications.

Язык: Английский

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Identifying Luminol Electrochemiluminescence at the Cathode via Single-Atom Catalysts Tuned Oxygen Reduction Reaction

Journal of the American Chemical Society, Год журнала: 2022, Номер 144(17), С. 7741 - 7749

Опубликована: Апрель 19, 2022

Luminol-based electrochemiluminescence (ECL) can be readily excited by various reactive oxygen species (ROS) electrogenerated with an reduction reaction (ORR). However, the multiple active intermediates involved in ORR catalyzed complex nanomaterials lead to recognizing role of ROS still elusive. Moreover, suffering from absence direct electrochemical oxidation luminol at cathode and poor transformation efficiency O2 ROS, weak cathodic ECL emission is often neglected. Herein, owing tunable coordination environment structure-dependent catalytic feature, single-atom catalysts (SACs) are employed uncover relationship between intrinsic activity behavior. Interestingly, traditionally negligible first boosted (ca. 70-fold) combination via SACs chemical luminol. The exhibits electron-transfer pathway-dependent response adjusting surrounding center metal atoms a controlled way selectively produce different intermediates. This work bridges performance behavior, which will guide development amplified sensing platform through rational tailoring potential-resolved assays based on high-efficiency reported.

Язык: Английский

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Carboranes in drug discovery, chemical biology and molecular imaging

Nature Reviews Chemistry, Год журнала: 2022, Номер 6(7), С. 486 - 504

Опубликована: Июнь 23, 2022

Язык: Английский

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Cas12a-based electrochemiluminescence biosensor for target amplification-free DNA detection

Biosensors and Bioelectronics, Год журнала: 2021, Номер 176, С. 112954 - 112954

Опубликована: Янв. 1, 2021

Язык: Английский

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Aggregation-Induced Electrochemiluminescence Frame of Silica-Confined Tetraphenylethylene Derivative Matrixes for CD44 Detection via Peptide Recognition

Analytical Chemistry, Год журнала: 2023, Номер 95(16), С. 6725 - 6731

Опубликована: Апрель 11, 2023

The theory of aggregation-induced electrochemiluminescence (AIECL) has introduced new vitality into preparing (ECL) emitters. However, the progress in application biosensing analysis been slow owing to lack AIECL-based functional nanomaterials. Herein, a biosensor was fabricated using mesoporous silica nanosphere (MSN) matrix-confined 1,1,2,2-tetra(4-carboxylphenyl)ethylene (TPE) as well-ordered ECL emitter and self-designed WHPWSYC (WC-7) heptapeptide target capturer for CD44 detection. TPE its co-reactant, triethylamine (TEA), were encapsulated MSN nanomatrix enhance radiation transition by limiting intramolecular rotation molecule benefit from spatial confinement effect, intensity is self-enhanced replacing electron free diffusion conventional system. MSN-TPE-TEA can act satisfactory sensing substrates that improve reproducibility batch-to-batch consistency biosensors functions stable signal label trace biomarkers. As substitute antibody hyaluronic acid, WC-7 significantly reduced steric hindrance interface affinity tests. Combined with DNA strand displacement reaction, this strategy shows good response standard antigen MCF-7 cells different concentrations, which another feasible method detecting body fluids or living cells.

Язык: Английский

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Self‐assembly Induced Enhanced Electrochemiluminescence of Copper Nanoclusters Using DNA Nanoribbon Templates

Angewandte Chemie International Edition, Год журнала: 2023, Номер 62(21)

Опубликована: Март 23, 2023

Abstract Copper nanoclusters (CuNCs) are attractive electrochemiluminescence (ECL) emitters as Cu is comparatively inexpensive, nontoxic, and highly abundant. However, their ECL yield relatively low. Herein, we report that orderly self‐assembly of CuNCs using DNA nanoribbon the template (DNR/CuNCs) conferred with improved properties compared individual in both annihilation co‐reactant processes. The DNR/CuNCs resulted a high 46.8 % K 2 S O 8 , which was ≈68 times higher than CuNCs. This strategy successfully extended to other emitters, such gold Ru(bpy) 3 2+ /TPrA system. Furthermore, an application DNR/CuNCs, DNR/CuNC‐based biosensor sensitivity constructed for dopamine determination (two orders magnitude lower previously reported), showing have potential bioanalysis new type superior luminophore candidate.

Язык: Английский

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