
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Окт. 25, 2024
Язык: Английский
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Окт. 25, 2024
Язык: Английский
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Март 20, 2025
We develop herein an efficient copper-catalyzed dihydroboration of alkynes with HBpin to synthesize gem-diborylalkanes. This catalytic process features a broad substrate scope, good functional group tolerance, and excellent regioselectivity. Notably, the gram-scale reaction further product derivatizations demonstrate practicality this protocol. Preliminary mechanistic studies indicate that involves hydroboration alkyne vinylboronate intermediate.
Язык: Английский
Процитировано
0Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Апрель 3, 2025
The carbanion derived from chlorodiborylmethane can act as a soft nucleophile, while the halogen substituent subsequently function leaving group. Taking advantage of this feature, we herein have developed an efficient synthesis gem-diborylcyclopropyl ketones diverse range enone substrates. We also demonstrated synthetic utility protocol by leveraging highly transformable nature cyclopropyl moiety and C-B bonds.
Язык: Английский
Процитировано
0Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Апрель 11, 2025
Herein, we disclose a manganese-catalyzed approach that enables the direct iododiborylcarbofunctionalization of alkynes with (diboronmethyl)iodide under mild conditions. This grants access to range structurally unique and synthetically useful γ-iodine-substituted gem-bis(boronate)s, which have hitherto been inaccessible. atom-economical strategy displays excellent functional-group tolerance, encompasses wide applicable substrates, demonstrates high Z:E selectivity (up 96:4).
Язык: Английский
Процитировано
0Chem, Год журнала: 2024, Номер unknown
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
2Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Окт. 25, 2024
Язык: Английский
Процитировано
2