Axially chiral α-boryl-homoallenyl boronic esters as versatile toolbox for accessing centrally and axially chiral molecules DOI Creative Commons

Yonghoon Jin,

Junseok Lee,

Woohyun Jo

и другие.

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 25, 2024

Язык: Английский

Copper-Catalyzed Regioselective Dihydroboration of Alkynes to Construct gem-Diborylalkanes DOI
Wenke Dong,

Zheming Liu,

Minghao Zhang

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 20, 2025

We develop herein an efficient copper-catalyzed dihydroboration of alkynes with HBpin to synthesize gem-diborylalkanes. This catalytic process features a broad substrate scope, good functional group tolerance, and excellent regioselectivity. Notably, the gram-scale reaction further product derivatizations demonstrate practicality this protocol. Preliminary mechanistic studies indicate that involves hydroboration alkyne vinylboronate intermediate.

Язык: Английский

Процитировано

0
Synthesis of gem-Diborylcyclopropyl Ketones via Conjugate Addition of Chlorodiborylmethane to α,β-Unsaturated Ketones DOI
Shuang Xu,

Peng‐Fei Ning,

Yi Wei

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 3, 2025

The carbanion derived from chlorodiborylmethane can act as a soft nucleophile, while the halogen substituent subsequently function leaving group. Taking advantage of this feature, we herein have developed an efficient synthesis gem-diborylcyclopropyl ketones diverse range enone substrates. We also demonstrated synthetic utility protocol by leveraging highly transformable nature cyclopropyl moiety and C-B bonds.

Язык: Английский

Процитировано

0
Synthesis of γ-Iodo-allylic Diboronic Esters via Atom Transfer Radical Addition of (Diborylmethyl)iodide to Alkynes DOI
Kun Zhang, Junling Zhang, Qing He

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 11, 2025

Herein, we disclose a manganese-catalyzed approach that enables the direct iododiborylcarbofunctionalization of alkynes with (diboronmethyl)iodide under mild conditions. This grants access to range structurally unique and synthetically useful γ-iodine-substituted gem-bis(boronate)s, which have hitherto been inaccessible. atom-economical strategy displays excellent functional-group tolerance, encompasses wide applicable substrates, demonstrates high Z:E selectivity (up 96:4).

Язык: Английский

Процитировано

0
Atom swap in triple bonds via nitrogen-deletion coupling with gem-diborylalkanes DOI

Liangxuan Xu,

Du Chen, Peng Zhang

и другие.

Chem, Год журнала: 2024, Номер unknown

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

2
Axially chiral α-boryl-homoallenyl boronic esters as versatile toolbox for accessing centrally and axially chiral molecules DOI Creative Commons

Yonghoon Jin,

Junseok Lee,

Woohyun Jo

и другие.

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 25, 2024

Язык: Английский

Процитировано

2