Pure and Applied Chemistry,
Год журнала:
2022,
Номер
94(11-12), С. 1209 - 1224
Опубликована: Дек. 1, 2022
Abstract
Direct
deoxygenative
borylation
is
a
highly
enabling
chemical
transformation
considering
the
attractive
synthetic
features
of
oxygenous
feedstocks
and
organoboron
compounds.
Despite
ranking
among
ideality
in
different
settings,
such
space
remained
largely
uncharted
underutilized
until
recent
decades.
This
short
review
will
summarize
some
key
advances
field
direct
deoxy-borylation
alcohols,
ethers,
aldehydes,
ketones,
carboxylic
acids
organize
these
contributions
based
on
substrate
classes.
In
each
representative,
general
features,
including
reaction
conditions,
product
scopes
mechanistic
insights,
be
highlighted
discussed.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(14), С. 3544 - 3552
Опубликована: Янв. 1, 2023
Here,
we
report
a
Mo-catalyzed
carbonyl–carbonyl
olefination
reaction
for
the
syntheses
of
several
heterocycles,
such
as
indoles,
benzofurans,
benzothiophene,
2-pyrone,
coumarins
and
their
derivatives.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 18, 2024
Functional
group-directed
site-
and
enantioselective
C(sp3)–H
functionalization
of
alcohols
or
masked
represents
a
formidable
challenge.
We
herein
report
the
first
example
iridium-catalyzed
asymmetric
α-C(sp3)–H
borylation
primary
alcohol-derived
carbamates
by
judicious
choice
directing
groups.
A
variety
chiral
borylated
were
obtained
with
good
to
high
enantioselectivities.
also
demonstrated
synthetic
utility
taking
advantage
highly
transformable
feature
C–B
bonds
leaving
ability
carbamates.
Chinese Journal of Chemistry,
Год журнала:
2023,
Номер
41(24), С. 3593 - 3597
Опубликована: Сен. 10, 2023
Comprehensive
Summary
Aldehydes
are
a
kind
of
important
synthons
and
reagents
in
organic
synthesis.
The
efforts
on
transformations
aldehydes
highly
rewarding
have
always
attracted
considerable
attention.
Herein,
cross‐coupling
with
α‐haloboronates
has
been
achieved
under
dual
nickel/photoredox
catalysis
system.
Considering
the
can
be
easily
obtained
from
our
deoxygenative
difunctionalization
carbonyls
(DODC)
strategy,
this
protocol
provides
formal
to
one‐carbon‐prolonged
ketone
products.
mild
conditions
enabled
good
functional
group
tolerance
broad
substrate
applicability.
application
method
was
presented
via
tunable
synthesis
two
ketones
very
similar
skeletons
same
aldehydes.
ACS Organic & Inorganic Au,
Год журнала:
2023,
Номер
4(1), С. 1 - 25
Опубликована: Окт. 25, 2023
Radical
reactions
have
recently
experienced
a
resurgence
in
organic
chemistry
after
many
decades
of
being
considered
to
be
too
unselective
offer
viable
solution
for
complex
synthetic
problems.
intermediates
often
number
different
reaction
pathways
available
them
that
are
all
associated
with
insubstantial
barriers
so
outcomes
can
controlled
by
proximity
and
dynamics.
Cage
effects
consist
the
effect
surrounding
medium,
such
as
solvent
or
enzyme
pocket,
on
movement
radical
medium's
resulting
influence
over
selectivity.
substantially
affect
outcome
transformations
condensed
phases,
which
feature
intermediacy
pairs,
suitable
choice
cage
should
thus
constitute
key
optimization
parameter
reactions.
This
Perspective
provides
an
overview
aspects
importance
highlights
its
role
reported
forge
C-X
bonds
via
radicals.
Synlett,
Год журнала:
2023,
Номер
34(10), С. 1075 - 1078
Опубликована: Янв. 16, 2023
Abstract
By
merging
nickel
catalysis
and
photochemistry,
we
developed
a
deoxygenative
alkylboration
of
aldehydes
via
difunctionalization
carbonyls
strategy.
This
three-component
reaction
between
alkyl
halides,
B2Pin2,
represents
one
the
most
efficient
methods
to
furnish
versatile
secondary
α,α-dialkyl
boronates.
A
series
skeletons
can
be
gained
from
products
based
on
carbon–boron
bond
transformation.
In
addition,
arylboration
was
achieved.
Angewandte Chemie,
Год журнала:
2023,
Номер
135(18)
Опубликована: Март 8, 2023
Abstract
Transition‐metal‐catalyzed
asymmetric
carbon−carbon
bond
formation
to
forge
phosphonates
with
an
α‐chiral
carbon
center
through
C(sp
3
)−C(sp
)
and
2
couplings
has
been
successful.
However,
the
enantioselective
C(sp)−C(sp
coupling
not
yet
disclosed.
Reported
herein
is
unprecedented
enantioconvergent
cross‐coupling
of
alkynyl
bromides
α‐bromo
deliver
chiral
α‐alkynyl
phosphonates.
Pure and Applied Chemistry,
Год журнала:
2022,
Номер
94(11-12), С. 1209 - 1224
Опубликована: Дек. 1, 2022
Abstract
Direct
deoxygenative
borylation
is
a
highly
enabling
chemical
transformation
considering
the
attractive
synthetic
features
of
oxygenous
feedstocks
and
organoboron
compounds.
Despite
ranking
among
ideality
in
different
settings,
such
space
remained
largely
uncharted
underutilized
until
recent
decades.
This
short
review
will
summarize
some
key
advances
field
direct
deoxy-borylation
alcohols,
ethers,
aldehydes,
ketones,
carboxylic
acids
organize
these
contributions
based
on
substrate
classes.
In
each
representative,
general
features,
including
reaction
conditions,
product
scopes
mechanistic
insights,
be
highlighted
discussed.
