Three-component tandem remote C-H functionalization of naphthalenes by ruthenium catalysis: Modular and concise synthesis of multifunctional naphthalenes DOI Creative Commons

Mao‐Gui Huang,

Yue-Liu-Ting Fu,

Jia‐Wei Li

и другие.

Chemical Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 12, 2024

A versatile multi-component strategy for synthesizing multi-functional naphthalenes via ruthenium-catalyzed tandem C5–H functionalization from readily available naphthalene, olefin and alkyl bromide compounds is disclosed.

Язык: Английский

Assembly of Heterocyclic C-Glycosides by Ru-Catalyzed C–H Activation/Cyclization with Carbonyl Sulfoxonium Ylide Glyco-Reagents DOI

Deng-Yin Liu,

Pengfei Wang,

Yu-Jun Ruan

и другие.

Organic Letters, Год журнала: 2024, Номер 26(24), С. 5092 - 5097

Опубликована: Июнь 7, 2024

New carbonyl sulfoxonium ylide glyco-reagents have been developed, enabling the synthesis of versatile heteroarene C-glycosides through a Ru-catalyzed C–H activation/annulation strategy. These reactions tolerate various saccharide donors and represent significant advance in stereoselective heterocyclic C-glycosides. Furthermore, strategy methods could be applied to large-scale late-stage modifications some structurally complex natural products or drugs.

Язык: Английский

Процитировано

2
Synthesis of C-glycosides enabled by palladium-catalyzed glycosylation reactions DOI

Wenli Tong,

Jie‐Ping Wan, Jianchao Liu

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(23), С. 6918 - 6941

Опубликована: Янв. 1, 2024

This review highlights the recent progress in palladium-catalyzed C -glycosylation reactions for synthesis of -glycosides.

Язык: Английский

Процитировано

2
Visible-light-promoted direct desulfurization of glycosyl thiols to access C-glycosides DOI Creative Commons

Demeng Xie,

Wei Zeng, Jian Yang

и другие.

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 24, 2024

C-Glycosides are essential for the study of biological processes and development carbohydrate-based drugs. Despite tremendous hurdles, glycochemists have often fantasized about efficient, highly stereoselective synthesis C-glycosides with shortest steps under mild conditions. Herein, we report a desulfurative radical protocol to synthesize C-alkyl glycosides coumarin visible-light induced conditions without need an extra photocatalyst, in which stable readily available glycosyl thiols that could be obtained from native sugars activated situ by pentafluoropyridine. The benefits this procedure include high stereoselectivity, broad substrate scope, easy handling. Mechanistic studies indicate produced tetrafluoropyridyl S-glycosides form key electron donor-acceptor (EDA) complexes Hantzsch ester (for glycosides) or Et

Язык: Английский

Процитировано

2
Synthesis of C-Oligosaccharides via Ni-Catalyzed Reductive Hydroglycosylation DOI

Tayyab Gulzar,

Yanhua Liu,

Yu‐Nong Xia

и другие.

Organic Letters, Год журнала: 2024, Номер 26(8), С. 1718 - 1722

Опубликована: Фев. 21, 2024

-Oligosaccharides are metabolically stable surrogates of native glycans containing

Язык: Английский

Процитировано

1
Three-component tandem remote C-H functionalization of naphthalenes by ruthenium catalysis: Modular and concise synthesis of multifunctional naphthalenes DOI Creative Commons

Mao‐Gui Huang,

Yue-Liu-Ting Fu,

Jia‐Wei Li

и другие.

Chemical Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 12, 2024

A versatile multi-component strategy for synthesizing multi-functional naphthalenes via ruthenium-catalyzed tandem C5–H functionalization from readily available naphthalene, olefin and alkyl bromide compounds is disclosed.

Язык: Английский

Процитировано

1