Cobalt- or rhodium-catalyzed synthesis of 1,2-dihydrophosphete oxides via C–H activation and formal phosphoryl migration

Chemical Science, Год журнала: 2024, Номер 15(16), С. 6012 - 6021

Опубликована: Янв. 1, 2024

A highly stereo- and chemoselective intermolecular coupling of diverse heterocycles with dialkynylphosphine oxides has been realized

Язык: Английский

---

Spot the difference in reactivity: a comprehensive review of site-selective multicomponent conjugation exploiting multi-azide compounds

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

This review outlines methods and strategies to exploit specific azide positions for molecular conjugation in the presence of multiple azido groups. Illustrative examples spanning di-, tri- tetraazide click scaffolds are included.

Язык: Английский

---

Conversion of Alkyl Azides to Diazo Compounds and the Azide-Site Selectivity: One-Pot Phosphine-Mediated Transient Protection of Azido Groups and Deprotective Transformation to Diazo Groups

Опубликована: Фев. 9, 2024

A one-pot conversion of alkyl azides to diazo compounds is outlined. After azido group protection α-azidocarbonyl compounds, treatment the resulting phosphazides with silica gel in a wet solvent afforded α-diazo carbonyl products by azide-deprotective conversion. Competitive reactions α-azido amides and aryl demonstrate azide-site selectivity. Azide-site selective click functionalization this sequence also demonstrated diazido compounds.

Язык: Английский

---

Amphos-Mediated Conversion of Alkyl Azides to Diazo Compounds and One-Pot Azide-Site Selective Transient Protection, Click Conjugation, and Deprotective Transformation

Organic Letters, Год журнала: 2024, Номер 26(12), С. 2409 - 2413

Опубликована: Март 19, 2024

A one-pot conversion of alkyl azides to diazo compounds is outlined. After the reaction α-azidocarbonyl with Amphos, treatment resulting phosphazides silica gel in a wet solvent afforded α-diazo carbonyl products. Through azido group protection property inter- and intramolecular azide-site selective reactions protection, click functionalization, deprotection have been demonstrated one pot.

Язык: Английский

---

Effect of Substituents in Governing the Homolytic Gas-Phase P–H Bond Dissociation Enthalpies of Phosphine-type Oxides (R1R2P(=O)H)

Chemical Data Collections, Год журнала: 2024, Номер unknown, С. 101164 - 101164

Опубликована: Сен. 1, 2024

Язык: Английский

---