Journal of Polymer Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 10, 2024
ABSTRACT
The
growing
demand
for
lipid–polymer
conjugates
(LPCs)
in
biomedicine
highlights
the
need
efficient
synthesis
methods.
This
study
presents
a
novel
Y‐type
photoiniferter
reagent
(Lipid‐PIT)
with
diethyldithiocarbamate
group
and
diacylglycerol
group.
Lipid‐PIT
efficiently
initiated
polymerization
of
vinyl
monomers
such
as
oligo(ethylene
glycol)
methacrylate
(OEGMA),
N
,
‐dimethylacrylamide
(DMA),
tert
‐butyl
acrylate
(tBA),
n
(
BA)
under
UV
irradiation
at
room
temperature,
yielding
LPCs.
Proton
NMR
confirmed
presence
moieties
chain
ends.
kinetics
DMA
showed
linear
increase
molecular
weight
M
)
time,
polydispersity
(Đ)
below
1.50,
demonstrating
high
controllability.
Moreover,
allows
creation
block
copolymers
via
secondary
extension.
In
vitro
assays
revealed
that
LPCs
synthesized
from
OEGMA
successfully
modified
L929
HeLa
cell
surfaces
exhibited
good
biocompatibility.
offers
rapid,
method
LPC
promising
biomedical
applications.
Macromolecules,
Год журнала:
2024,
Номер
57(5), С. 2432 - 2445
Опубликована: Фев. 23, 2024
We
report
a
new
one-pot
low-viscosity
synthetic
route
to
high
molecular
weight
non-ionic
water-soluble
polymers
based
on
polymerization-induced
self-assembly
(PISA).
The
RAFT
aqueous
dispersion
polymerization
of
N-acryloylmorpholine
(NAM)
is
conducted
at
30
°C
using
suitable
redox
initiator
and
poly(2-hydroxyethyl
acrylamide)
(PHEAC)
precursor
in
the
presence
0.60
M
ammonium
sulfate.
This
relatively
low
level
added
electrolyte
sufficient
salt
out
PNAM
block,
while
steric
stabilization
conferred
by
short
salt-tolerant
PHEAC
block.
A
mean
degree
(DP)
up
6000
was
targeted
for
NAM
conversions
(>96%)
were
obtained
all
cases.
On
dilution
with
deionized
water,
as-synthesized
sterically
stabilized
particles
undergo
dissociation
afford
molecularly
dissolved
chains,
as
judged
dynamic
light
scattering
1H
NMR
spectroscopy
studies.
DMF
GPC
analysis
confirmed
chain
extension
efficiency
precursor,
but
broad
distributions
observed
PHEAC–PNAM
diblock
copolymer
chains
(Mw/Mn
>
1.9).
has
been
many
other
PISA
formulations
when
targeting
core-forming
block
DPs
tentatively
attributed
transfer
polymer,
which
well
known
polyacrylamide-based
polymers.
In
fact,
dispersities
are
actually
desirable
if
such
copolymers
be
used
viscosity
modifiers
because
solution
correlates
closely
Mw.
Static
studies
also
conducted,
Zimm
plot
indicating
an
absolute
Mw
approximately
2.5
×
106
g
mol–1
DP
6000.
Finally,
it
emphasized
that
leads
sulfur
content
this
latter
formulation
just
23
ppm,
minimizes
cost,
color,
malodor
associated
organosulfur
agent.
ACS Macro Letters,
Год журнала:
2025,
Номер
unknown, С. 306 - 312
Опубликована: Фев. 21, 2025
Simultaneous
control
over
macromolecular
chain
topology,
molecular
weight,
and
dispersity
is
an
important
synthetic
goal
in
polymer
chemistry.
The
synthesis
of
well-defined
poly(methyl
acrylate)
star
polymers
with
ultrahigh
weights
(>106
g
mol-1)
tunable
dispersities
realized
for
the
first
time
via
blue
light-controlled
photoiniferter
polymerization
using
a
tetrafunctional
switchable
RAFT
agent
(SRA4).
spectroscopic
properties
activity
SRA4
can
be
reversibly
tuned
by
addition
acid/base.
For
example,
protonation
4-toluenesulfonic
acid
(TsOH)
leads
to
enhanced
UV-visible
light
absorption,
faster
rate,
lower
resulting
polymer.
Star
were
prepared
predicted
(Mn
≈
80-1550
kg
(Đ
1.8-1.2)
when
targeting
degrees
range
1000-20000
presence
varying
amounts
TsOH.
High
end-group
fidelity
such
was
confirmed
one-pot
extension
experiments,
which
afforded
series
pseudoblock
copolymers
controlled
dispersities.
Finally,
rotational
rheology
used
examine
effect
dispersity,
topology
(whether
linear
or
star-shaped)
on
solution
viscosity.
Polymer Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
In
this
work,
we
highlight
the
impact
of
reaction
conditions
(
i.e.
monomer
conversion,
time,
and
light
intensity)
on
stability
thiocarbonylthio
group-containing
polymers
by
quantification
utilizing
TG-HPLC.
Russian Chemical Reviews,
Год журнала:
2025,
Номер
94(4), С. RCR5164 - RCR5164
Опубликована: Апрель 1, 2025
The
discovery
of
reversible
deactivation
radical
polymerization
(RDRP),
or
controlled
(CRP)
has
revolutionized
the
chemistry
synthetic
polymers.
This
strategy
opened
up
way
to
polymer
materials
with
architecture,
composition,
and
functions.
Currently,
owing
use
novel
approaches
related
chain
deactivation,
gone
beyond
synthesis.
It
can
be
used
obtain
not
only
macromolecular
organic
compounds,
but
also
organic-inorganic
hybrid
materials,
bioconjugates,
promising
polymers
for
electronics,
energy
production,
medicine,
other
high-tech
fields.
is
exceptionally
important
that
some
CRP
methods
have
a
clear-cut
environmental
component,
since
they
are
focused
on
compliance
most
principles
green
development
nature-like
processes
in
targeted
synthesis
well-defined
specified
set
properties
characteristics.
review
considers
particular
examples
analyzes
possible
prospects
practical
application
environmentally
benign
functional
A
comparative
analysis
performed
classical
living
wide
range
monomers
(reversible
inhibition,
addition
fragmentation
transfer,
atom
transfer
involving
transition
metal
complexes),
concept
photoredox
catalysis,
methodology
as
applied
gives
above
aspects,
including
procedural
details
photoinitiation
their
relationship
key
principles.
In
our
opinion,
this
will
interest
specialists
field
chemistry,
chemists
scientists.
<br>
bibliography
includes
242
references.
Journal of the American Chemical Society,
Год журнала:
2025,
Номер
147(19), С. 16390 - 16395
Опубликована: Апрель 30, 2025
Selectively
initiating
controlled
polymerizations
using
common
functional
groups
is
a
powerful
route
to
synthesizing
advanced
polymer
architectures.
Amines
are
one
of
the
most
in
small
molecules,
pharmaceuticals,
and
biomolecules,
thus
valuable
substituents
use
for
polymerizations.
In
this
study,
we
present
facile
initiation
radical
polymerization
from
α-carbon
primary
amine
via
an
electron
donor-acceptor
(EDA)
complex-triggered
deamination.
Through
method,
polymers
were
successfully
grafted
variety
amino
acid
derivatives.
The
resulting
had
good
matching
between
theoretical
experimental
molar
masses,
narrow
mass
distributions
(Đ
∼
1.1-1.2),
exceptional
α-chain
end
fidelities.
This
method
was
trialed
on
model
dipeptide,
demonstrating
viability
EDA-RAFT
synthesis
peptide-polymer
conjugates.
