Preparation of Lipid–Polymer Conjugates by Photoiniferter Polymerization and Application to Cell Surface Modification DOI Open Access
Wenjin Wang, Shengjie Liu,

Yijia Yu

и другие.

Journal of Polymer Science, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 10, 2024

ABSTRACT The growing demand for lipid–polymer conjugates (LPCs) in biomedicine highlights the need efficient synthesis methods. This study presents a novel Y‐type photoiniferter reagent (Lipid‐PIT) with diethyldithiocarbamate group and diacylglycerol group. Lipid‐PIT efficiently initiated polymerization of vinyl monomers such as oligo(ethylene glycol) methacrylate (OEGMA), N , ‐dimethylacrylamide (DMA), tert ‐butyl acrylate (tBA), n ( BA) under UV irradiation at room temperature, yielding LPCs. Proton NMR confirmed presence moieties chain ends. kinetics DMA showed linear increase molecular weight M ) time, polydispersity (Đ) below 1.50, demonstrating high controllability. Moreover, allows creation block copolymers via secondary extension. In vitro assays revealed that LPCs synthesized from OEGMA successfully modified L929 HeLa cell surfaces exhibited good biocompatibility. offers rapid, method LPC promising biomedical applications.

Язык: Английский

Control of Molecular Weight Distribution through Photoresponsive RAFT Polymerization with a Temporal Program-Controlled System DOI

Jie Sui,

Xiaoyu Miao,

Xin Cao

и другие.

Polymer, Год журнала: 2024, Номер unknown, С. 127863 - 127863

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

1
Polymer dispersity modulation by statistical copolymerization of (α-alkyl)acrylate monomers with disparate reactivity: Enhanced monomer conversion and tailored dispersity for dielectric elastomer application DOI
Keling Hu, Yaojing Zhang, Shun Liu

и другие.

European Polymer Journal, Год журнала: 2024, Номер 216, С. 113265 - 113265

Опубликована: Июнь 27, 2024

Язык: Английский

Процитировано

0
Preparation of Lipid–Polymer Conjugates by Photoiniferter Polymerization and Application to Cell Surface Modification DOI Open Access
Wenjin Wang, Shengjie Liu,

Yijia Yu

и другие.

Journal of Polymer Science, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 10, 2024

ABSTRACT The growing demand for lipid–polymer conjugates (LPCs) in biomedicine highlights the need efficient synthesis methods. This study presents a novel Y‐type photoiniferter reagent (Lipid‐PIT) with diethyldithiocarbamate group and diacylglycerol group. Lipid‐PIT efficiently initiated polymerization of vinyl monomers such as oligo(ethylene glycol) methacrylate (OEGMA), N , ‐dimethylacrylamide (DMA), tert ‐butyl acrylate (tBA), n ( BA) under UV irradiation at room temperature, yielding LPCs. Proton NMR confirmed presence moieties chain ends. kinetics DMA showed linear increase molecular weight M ) time, polydispersity (Đ) below 1.50, demonstrating high controllability. Moreover, allows creation block copolymers via secondary extension. In vitro assays revealed that LPCs synthesized from OEGMA successfully modified L929 HeLa cell surfaces exhibited good biocompatibility. offers rapid, method LPC promising biomedical applications.

Язык: Английский

Процитировано

0