Neural Regeneration Research,
Год журнала:
2024,
Номер
20(12), С. 3501 - 3516
Опубликована: Дек. 16, 2024
Vision
restoration
presents
a
considerable
challenge
in
the
realm
of
regenerative
medicine,
while
recent
progress
ultrasound
stimulation
has
displayed
potential
as
non-invasive
therapeutic
approach.
This
narrative
review
offers
comprehensive
overview
current
research
on
ultrasound-stimulated
neuromodulation,
emphasizing
its
treatment
modality
for
various
nerve
injuries.
By
examining
efficacy
different
types
modulating
peripheral
and
optic
nerves,
we
can
delve
into
their
underlying
molecular
mechanisms.
Furthermore,
underscores
sonogenetics
vision
restoration,
which
involves
leveraging
pharmacological
genetic
manipulations
to
inhibit
or
enhance
expression
related
mechanosensitive
channels,
thereby
strength
response.
We
also
address
how
methods
such
viral
transcription
be
utilized
render
specific
neurons
organs
highly
responsive
ultrasound,
leading
significantly
improved
outcomes.
Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 10, 2024
Abstract
The
diagnosis
and
treatment
of
cancer
face
significant
challenges.
Thus,
precise
controllable
methods
for
effective
tumor
management
are
required.
Sonogenetics
which
combines
ultrasound
technology
with
genetic
engineering
provides
a
promising
solution.
This
approach
utilizes
the
non‐invasive
nature
deep
tissue
penetration
capabilities
to
enable
diagnostics
targeted
therapies
cancer.
review
explores
roles
sonogenetics‐mediated
in
theranostics.
fundamental
properties
mechanisms
underlying
sonogenetics
first
introduced.
Then,
this
work
summarizes
representative
applications
therapy,
including
cell‐based
therapies,
bacteria‐based
eradication
cells.
Additionally,
diagnosis,
focusing
on
engineered
gas
vesicles
(GVs)
situ
generation
GVs
diagnostic
purposes
presented.
Finally,
challenges
clinical
translation
potential
well
discussed.
Neural Regeneration Research,
Год журнала:
2024,
Номер
20(12), С. 3501 - 3516
Опубликована: Дек. 16, 2024
Vision
restoration
presents
a
considerable
challenge
in
the
realm
of
regenerative
medicine,
while
recent
progress
ultrasound
stimulation
has
displayed
potential
as
non-invasive
therapeutic
approach.
This
narrative
review
offers
comprehensive
overview
current
research
on
ultrasound-stimulated
neuromodulation,
emphasizing
its
treatment
modality
for
various
nerve
injuries.
By
examining
efficacy
different
types
modulating
peripheral
and
optic
nerves,
we
can
delve
into
their
underlying
molecular
mechanisms.
Furthermore,
underscores
sonogenetics
vision
restoration,
which
involves
leveraging
pharmacological
genetic
manipulations
to
inhibit
or
enhance
expression
related
mechanosensitive
channels,
thereby
strength
response.
We
also
address
how
methods
such
viral
transcription
be
utilized
render
specific
neurons
organs
highly
responsive
ultrasound,
leading
significantly
improved
outcomes.
