Photomechanochemistry: harnessing mechanical forces to enhance photochemical reactions
Beilstein Journal of Organic Chemistry,
Год журнала:
2025,
Номер
21, С. 458 - 472
Опубликована: Март 3, 2025
Photomechanochemistry,
i.e.,
the
merger
of
light
energy
and
mechanical
forces,
is
emerging
as
a
new
trend
in
organic
synthesis,
enabling
unique
reactivities
fleeting
excited
states
under
solvent-minimized
conditions.
Despite
its
transformative
potential,
field
faces
significant
technological
challenges
that
must
be
addressed
to
unlock
full
capabilities.
In
this
Perspective,
we
analyze
selected
examples
showcase
available
technologies
combine
including
manual
grinding,
vortex
shaker
mixing,
rod
milling,
ball
milling.
By
examining
advantages
limitations
each
approach,
aim
provide
an
overview
current
state
synthetic
photomechanochemistry
identify
opportunities
for
future
advancements
rapidly
evolving
area
research.
Язык: Английский
Mechanochemical Ball Milling Approach to C(sp3)‐H Functionalization of 8‐Methylquinolines
ChemCatChem,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 23, 2024
Abstract
A
mechanochemical,
highly
regioselective
rhodium(III)‐catalyzed
C─H
methylation
of
8‐methylquinolines
is
reported.
The
method
reported
in
this
study,
often
solvent‐free
or
uses
minimal
solvent
(liquid
assisted
grinding),
operates
without
external
heating
under
mild
reaction
conditions,
demonstrating
tolerance
for
various
functional
groups.
Moreover,
the
time
significantly
reduced
compared
to
solvent‐based
variant.
Notably,
can
be
carried
out
using
a
pestle
and
mortar
instead
ball
milling
as
well,
highlighting
operational
simplicity
approach
achieving
challenging
C(sp
3
)‐H
activation
more
sustainable
conditions.
Язык: Английский