Recent advances in the design of SERS substrates and sensing systems for (bio)sensing applications: Systems from single cell to single molecule detection DOI Creative Commons
Sai Ratnakar Tadi,

Ashwini G Shenoy,

Anirudh Bharadwaj

и другие.

F1000Research, Год журнала: 2025, Номер 13, С. 670 - 670

Опубликована: Март 18, 2025

The Raman effect originates from spontaneous inelastic scattering of photons by matter. These provide a characteristic fingerprint this matter, and are extensively utilized for chemical biological sensing. inherently lower generation these scattered photons, do not hold potential their direct use in sensing applications. Surface enhanced spectroscopy (SERS) overcomes the low sensitivity associated with assists diverse analytes, including ions, small molecules, inorganics, organics, radionucleotides, cells. Plasmonic nanoparticles exhibit localized surface plasmon resonance (LSPR) when they closely spaced, create hotspots where electromagnetic field is significantly enhanced. This amplifies signal may offer up to 10 14-fold SERS enhancement. development active substrates requires further consideration optimization several critical features such as periodicity, hotspot density, mitigation sample or autofluorescence, tuning hydrophilicities, specific (bio) recognition elements suitable linkers bioconjugation chemistries, appropriate optics obtain relevant outcomes terms sensitivity, cross-sensitivity, limit detection, signal-to-noise ratio (SNR), stability, shelf-life, disposability. article comprehensively reviews recent advancements on disposable materials commercial grades paper, textiles, glasses, polymers, some blue-ray digital versatile discs (DVDs) SERS-active point-of-use (POU) technologies have been reviewed critiqued analyte detection resource-limited settings, highlighting prospects applications ranging single-molecule single-cell detection. We conclude possible avenues developing viable deployable sensors holding immense environmental monitoring, food safety biomedical diagnostics.

Язык: Английский

Three Generations of Surface Nanocomposites Based on Hexagonally Ordered Gold Nanoparticle Layers and Their Application for Surface-Enhanced Raman Spectroscopy DOI Creative Commons

Shireen Zangana,

Tomáš Lednický, Attila Bonyár

и другие.

Chemosensors, Год журнала: 2023, Номер 11(4), С. 235 - 235

Опубликована: Апрель 10, 2023

The fabrication technology of surface nanocomposites based on hexagonally ordered gold nanoparticle (AuNP) layers (quasi-arrays) and their possible application as surface-enhanced Raman spectroscopy (SERS) substrates are presented in this paper. prepared using a nanotextured template formed by porous anodic alumina (PAA) combined with thin-film deposition subsequent solid-state dewetting. Three types hexagonal arrangements were different D/D0 values (where D is the interparticle gap, D0 diameter ellipsoidal particles) large area (~cm2 range), namely, 0.65 ± 0.12, 0.33 0.10 0.21 0.09. transfer particle to transparent was optimized through three generations, advantages disadvantages each discussed detail. Such densely packed high hot-spot density tunable gaps very beneficial for SERS applications, demonstrated two practical examples. substrate-based enhancement factor determined experimentally DNA monolayer found be between 4 × 104 2 106 arrangements. We also sensing characteristics small dye molecule, rhodamine 6G (R6G). By optimizing experimental conditions (e.g., laser power refractive index measurement medium an ethylene-glycol/water mixture), concentrations low 10−16 M could detected at 633 nm excitation.

Язык: Английский

Процитировано

9

Nanogap nanowires and its applications in biosensing DOI Creative Commons
Alaa Kamal Yousif Dafhalla,

Th. S. Dhahi,

A. Wesam Al-Mufti

и другие.

Sensing and Bio-Sensing Research, Год журнала: 2024, Номер 44, С. 100638 - 100638

Опубликована: Март 20, 2024

Nanogap nanowires have gained attention for their potential applications in biosensing due to unique physical properties, such as high surface-to-volume ratios and enhanced sensitivity. These can be used electrodes electrochemical biosensors, improving the sensitivity selectivity of these devices. They also integrated into sensor platforms using mature nano-fabrication procedures. advancements offer great developing highly sensitive accurate biosensors various applications, including biomedical diagnostics, environmental monitoring, food safety. revolutionized field by providing accuracy detecting biological molecules. been fabrication segmented chemical sensing, allowing more precise targeted detection specific analytes. shown promise protein biomarker analysis, enabling ultra-sensitive biomarkers at low levels. This review provides an overview recent Nanowires biosensing.

Язык: Английский

Процитировано

3

Enhancing an in situ-grown Ag/Cu2O/copper foam SERS substrate via an electromagnetic–chemical synergistic mechanism for trace detection of organic dyes DOI

Mengyu Xu,

Sheng Zhang, Ziyu Zhou

и другие.

New Journal of Chemistry, Год журнала: 2025, Номер 49(6), С. 2153 - 2160

Опубликована: Янв. 1, 2025

In this study, Ag/Cu 2 O/copper foam SERS substrates were prepared by high-temperature annealing combined with in situ growth, which realised the effective detection of organic dyes, and showed certain capability for environmental protection.

Язык: Английский

Процитировано

0

Increase the Reliability of SERS Measurements for Sodium Metabisulfite Using Highly Uniform AgNPs on Plasma‐Treated PDMS Substrate DOI Open Access
Trung Nguyen,

Toan Duc Nguyen,

Thi Ha Lien Nghiem

и другие.

Surface and Interface Analysis, Год журнала: 2025, Номер unknown

Опубликована: Фев. 20, 2025

ABSTRACT The surface‐enhanced Raman scattering (SERS), dependent on metal nanoparticle substrate structure and morphology, presents a powerful analytic tool across diverse fields such as food safety, environmental analysis, biomedical. Hard materials Si, glass, are often used in experimental research. They highly stable easy to manufacture. However, the surfaces of actual samples usually have different shapes, making using rigid substrates challenging, so developing flexible SERS is necessary. In this study, we focused blanket polydimethylsiloxane (PDMS) by spin coating with area concealed treated argon plasma jet. plasma‐treated area, PDMS surface transformed into hydrophilic form, causing nanoparticles spread flat, even layer evaporate quickly, leading better effect when analyzing liquid samples. results show that limit detection (LOD) sodium metabisulfite (SM) up 0.01 mg/mL relative standard deviation (RSD) 15.88%.

Язык: Английский

Процитировано

0

Recent advances in the design of SERS substrates and sensing systems for (bio)sensing applications: Systems from single cell to single molecule detection DOI Creative Commons
Sai Ratnakar Tadi,

Ashwini G Shenoy,

Anirudh Bharadwaj

и другие.

F1000Research, Год журнала: 2025, Номер 13, С. 670 - 670

Опубликована: Март 18, 2025

The Raman effect originates from spontaneous inelastic scattering of photons by matter. These provide a characteristic fingerprint this matter, and are extensively utilized for chemical biological sensing. inherently lower generation these scattered photons, do not hold potential their direct use in sensing applications. Surface enhanced spectroscopy (SERS) overcomes the low sensitivity associated with assists diverse analytes, including ions, small molecules, inorganics, organics, radionucleotides, cells. Plasmonic nanoparticles exhibit localized surface plasmon resonance (LSPR) when they closely spaced, create hotspots where electromagnetic field is significantly enhanced. This amplifies signal may offer up to 10 14-fold SERS enhancement. development active substrates requires further consideration optimization several critical features such as periodicity, hotspot density, mitigation sample or autofluorescence, tuning hydrophilicities, specific (bio) recognition elements suitable linkers bioconjugation chemistries, appropriate optics obtain relevant outcomes terms sensitivity, cross-sensitivity, limit detection, signal-to-noise ratio (SNR), stability, shelf-life, disposability. article comprehensively reviews recent advancements on disposable materials commercial grades paper, textiles, glasses, polymers, some blue-ray digital versatile discs (DVDs) SERS-active point-of-use (POU) technologies have been reviewed critiqued analyte detection resource-limited settings, highlighting prospects applications ranging single-molecule single-cell detection. We conclude possible avenues developing viable deployable sensors holding immense environmental monitoring, food safety biomedical diagnostics.

Язык: Английский

Процитировано

0