F1000Research,
Год журнала:
2025,
Номер
13, С. 670 - 670
Опубликована: Март 18, 2025
The
Raman
effect
originates
from
spontaneous
inelastic
scattering
of
photons
by
matter.
These
provide
a
characteristic
fingerprint
this
matter,
and
are
extensively
utilized
for
chemical
biological
sensing.
inherently
lower
generation
these
scattered
photons,
do
not
hold
potential
their
direct
use
in
sensing
applications.
Surface
enhanced
spectroscopy
(SERS)
overcomes
the
low
sensitivity
associated
with
assists
diverse
analytes,
including
ions,
small
molecules,
inorganics,
organics,
radionucleotides,
cells.
Plasmonic
nanoparticles
exhibit
localized
surface
plasmon
resonance
(LSPR)
when
they
closely
spaced,
create
hotspots
where
electromagnetic
field
is
significantly
enhanced.
This
amplifies
signal
may
offer
up
to
10
14-fold
SERS
enhancement.
development
active
substrates
requires
further
consideration
optimization
several
critical
features
such
as
periodicity,
hotspot
density,
mitigation
sample
or
autofluorescence,
tuning
hydrophilicities,
specific
(bio)
recognition
elements
suitable
linkers
bioconjugation
chemistries,
appropriate
optics
obtain
relevant
outcomes
terms
sensitivity,
cross-sensitivity,
limit
detection,
signal-to-noise
ratio
(SNR),
stability,
shelf-life,
disposability.
article
comprehensively
reviews
recent
advancements
on
disposable
materials
commercial
grades
paper,
textiles,
glasses,
polymers,
some
blue-ray
digital
versatile
discs
(DVDs)
SERS-active
point-of-use
(POU)
technologies
have
been
reviewed
critiqued
analyte
detection
resource-limited
settings,
highlighting
prospects
applications
ranging
single-molecule
single-cell
detection.
We
conclude
possible
avenues
developing
viable
deployable
sensors
holding
immense
environmental
monitoring,
food
safety
biomedical
diagnostics.
Chemosensors,
Год журнала:
2023,
Номер
11(4), С. 235 - 235
Опубликована: Апрель 10, 2023
The
fabrication
technology
of
surface
nanocomposites
based
on
hexagonally
ordered
gold
nanoparticle
(AuNP)
layers
(quasi-arrays)
and
their
possible
application
as
surface-enhanced
Raman
spectroscopy
(SERS)
substrates
are
presented
in
this
paper.
prepared
using
a
nanotextured
template
formed
by
porous
anodic
alumina
(PAA)
combined
with
thin-film
deposition
subsequent
solid-state
dewetting.
Three
types
hexagonal
arrangements
were
different
D/D0
values
(where
D
is
the
interparticle
gap,
D0
diameter
ellipsoidal
particles)
large
area
(~cm2
range),
namely,
0.65
±
0.12,
0.33
0.10
0.21
0.09.
transfer
particle
to
transparent
was
optimized
through
three
generations,
advantages
disadvantages
each
discussed
detail.
Such
densely
packed
high
hot-spot
density
tunable
gaps
very
beneficial
for
SERS
applications,
demonstrated
two
practical
examples.
substrate-based
enhancement
factor
determined
experimentally
DNA
monolayer
found
be
between
4
×
104
2
106
arrangements.
We
also
sensing
characteristics
small
dye
molecule,
rhodamine
6G
(R6G).
By
optimizing
experimental
conditions
(e.g.,
laser
power
refractive
index
measurement
medium
an
ethylene-glycol/water
mixture),
concentrations
low
10−16
M
could
detected
at
633
nm
excitation.
Sensing and Bio-Sensing Research,
Год журнала:
2024,
Номер
44, С. 100638 - 100638
Опубликована: Март 20, 2024
Nanogap
nanowires
have
gained
attention
for
their
potential
applications
in
biosensing
due
to
unique
physical
properties,
such
as
high
surface-to-volume
ratios
and
enhanced
sensitivity.
These
can
be
used
electrodes
electrochemical
biosensors,
improving
the
sensitivity
selectivity
of
these
devices.
They
also
integrated
into
sensor
platforms
using
mature
nano-fabrication
procedures.
advancements
offer
great
developing
highly
sensitive
accurate
biosensors
various
applications,
including
biomedical
diagnostics,
environmental
monitoring,
food
safety.
revolutionized
field
by
providing
accuracy
detecting
biological
molecules.
been
fabrication
segmented
chemical
sensing,
allowing
more
precise
targeted
detection
specific
analytes.
shown
promise
protein
biomarker
analysis,
enabling
ultra-sensitive
biomarkers
at
low
levels.
This
review
provides
an
overview
recent
Nanowires
biosensing.
New Journal of Chemistry,
Год журнала:
2025,
Номер
49(6), С. 2153 - 2160
Опубликована: Янв. 1, 2025
In
this
study,
Ag/Cu
2
O/copper
foam
SERS
substrates
were
prepared
by
high-temperature
annealing
combined
with
in
situ
growth,
which
realised
the
effective
detection
of
organic
dyes,
and
showed
certain
capability
for
environmental
protection.
Surface and Interface Analysis,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 20, 2025
ABSTRACT
The
surface‐enhanced
Raman
scattering
(SERS),
dependent
on
metal
nanoparticle
substrate
structure
and
morphology,
presents
a
powerful
analytic
tool
across
diverse
fields
such
as
food
safety,
environmental
analysis,
biomedical.
Hard
materials
Si,
glass,
are
often
used
in
experimental
research.
They
highly
stable
easy
to
manufacture.
However,
the
surfaces
of
actual
samples
usually
have
different
shapes,
making
using
rigid
substrates
challenging,
so
developing
flexible
SERS
is
necessary.
In
this
study,
we
focused
blanket
polydimethylsiloxane
(PDMS)
by
spin
coating
with
area
concealed
treated
argon
plasma
jet.
plasma‐treated
area,
PDMS
surface
transformed
into
hydrophilic
form,
causing
nanoparticles
spread
flat,
even
layer
evaporate
quickly,
leading
better
effect
when
analyzing
liquid
samples.
results
show
that
limit
detection
(LOD)
sodium
metabisulfite
(SM)
up
0.01
mg/mL
relative
standard
deviation
(RSD)
15.88%.
F1000Research,
Год журнала:
2025,
Номер
13, С. 670 - 670
Опубликована: Март 18, 2025
The
Raman
effect
originates
from
spontaneous
inelastic
scattering
of
photons
by
matter.
These
provide
a
characteristic
fingerprint
this
matter,
and
are
extensively
utilized
for
chemical
biological
sensing.
inherently
lower
generation
these
scattered
photons,
do
not
hold
potential
their
direct
use
in
sensing
applications.
Surface
enhanced
spectroscopy
(SERS)
overcomes
the
low
sensitivity
associated
with
assists
diverse
analytes,
including
ions,
small
molecules,
inorganics,
organics,
radionucleotides,
cells.
Plasmonic
nanoparticles
exhibit
localized
surface
plasmon
resonance
(LSPR)
when
they
closely
spaced,
create
hotspots
where
electromagnetic
field
is
significantly
enhanced.
This
amplifies
signal
may
offer
up
to
10
14-fold
SERS
enhancement.
development
active
substrates
requires
further
consideration
optimization
several
critical
features
such
as
periodicity,
hotspot
density,
mitigation
sample
or
autofluorescence,
tuning
hydrophilicities,
specific
(bio)
recognition
elements
suitable
linkers
bioconjugation
chemistries,
appropriate
optics
obtain
relevant
outcomes
terms
sensitivity,
cross-sensitivity,
limit
detection,
signal-to-noise
ratio
(SNR),
stability,
shelf-life,
disposability.
article
comprehensively
reviews
recent
advancements
on
disposable
materials
commercial
grades
paper,
textiles,
glasses,
polymers,
some
blue-ray
digital
versatile
discs
(DVDs)
SERS-active
point-of-use
(POU)
technologies
have
been
reviewed
critiqued
analyte
detection
resource-limited
settings,
highlighting
prospects
applications
ranging
single-molecule
single-cell
detection.
We
conclude
possible
avenues
developing
viable
deployable
sensors
holding
immense
environmental
monitoring,
food
safety
biomedical
diagnostics.