Recent development of Schiff-base metal complexes as therapeutic agents for lung cancer
Journal of Molecular Structure,
Год журнала:
2024,
Номер
1318, С. 139403 - 139403
Опубликована: Июль 22, 2024
Язык: Английский
Metal-Based Drug–DNA Interactions and Analytical Determination Methods
Molecules,
Год журнала:
2024,
Номер
29(18), С. 4361 - 4361
Опубликована: Сен. 13, 2024
DNA
structure
has
many
potential
places
where
endogenous
compounds
and
xenobiotics
can
bind.
Therefore,
bind
along
the
sites
of
nucleic
acid
with
aim
changing
its
structure,
genetic
message,
and,
implicitly,
functions.
Currently,
there
are
several
mechanisms
known
to
be
involved
in
binding.
These
covalent
non-covalent
interactions.
The
interaction
or
metal
base
coordination
is
an
irreversible
binding
it
represented
by
intra-/interstrand
cross-link.
generally
a
reversible
intercalation
between
pairs,
insertion,
major
and/or
minor
groove
binding,
electrostatic
interactions
sugar
phosphate
backbone.
In
present
review,
we
focus
on
types
DNA-metal
complex
(including
some
representative
examples)
presenting
methods
currently
used
study
them.
Язык: Английский
Two multifunctional zero-dimensional Gd(III) complexes: Magnetocaloric effect, inhibition of cell proliferation, migration and induction of apoptosis in lung cancer cells
Journal of Inorganic Biochemistry,
Год журнала:
2025,
Номер
265, С. 112832 - 112832
Опубликована: Янв. 22, 2025
Язык: Английский
Investigation of DNA Binding and Antibacterial Properties of a Zn(II) Complex with an N2OS Salophen-type Ligand
Journal of Molecular Structure,
Год журнала:
2025,
Номер
unknown, С. 142431 - 142431
Опубликована: Апрель 1, 2025
Язык: Английский
Indium Complexes with 2-((Pyridin-4-Ylmethylene)Amino)Phenols: Synthesis, Structure and Spectroscopic Properties
Опубликована: Янв. 1, 2025
Язык: Английский
A biophysical insight into the mechanism of anticancer activity of salicylidene cyclohexanediamine based cobalt and nickel complexes through CT-DNA, BSA binding and docking study
Journal of Molecular Structure,
Год журнала:
2024,
Номер
1322, С. 140285 - 140285
Опубликована: Окт. 6, 2024
Язык: Английский
Design and synthesis of a new pyrazole-naphthalene Schiff base: Al3+ recognition, DNA binding studies and theoretical calculations
Yanling Pang,
Xinshu Long,
Xiaomin Jin
и другие.
Journal of Molecular Structure,
Год журнала:
2024,
Номер
1317, С. 139095 - 139095
Опубликована: Дек. 1, 2024
Язык: Английский
Mononuclear Copper(II) Complexes with Polypyridyl Ligands: Synthesis, Characterization, DNA Interactions/Cleavages and in vitro Cytotoxicity towards Human Cancer Cells
Dalton Transactions,
Год журнала:
2024,
Номер
53(28), С. 11697 - 11712
Опубликована: Янв. 1, 2024
DNA
being
the
necessary
element
in
cell
regeneration,
controlled
cellular
apoptosis
Язык: Английский
A Simple and Rapid “Turn-On” Fluorescent Probe Based on Binuclear Schiff Base for Zn2+ and Its Application in Cell Imaging and Test Strips
Molecules,
Год журнала:
2024,
Номер
29(24), С. 5850 - 5850
Опубликована: Дек. 11, 2024
A
series
of
colorful
binuclear
Schiff
bases
derived
from
the
different
diamine
bridges
including
1,2-
ethylenediamine
(bis-Et-SA,
bis-Et-4-NEt2,
bis-Et-5-NO2,
bis-Et-Naph),
1,2-phenylenediamine
(bis-Ph-SA,
bis-Ph-4-NEt2,
bis-Ph-5-NO2,
bis-Ph-Naph),
dicyano-1,2-ethenediamine
(bis-CN-SA,
bis-CN-4-NEt2,
bis-CN-5-NO2,
bis-CN-Naph)
have
been
designed
and
prepared.
The
optical
properties
these
base
ligands
were
fully
determined
by
UV–Vis
absorption
spectroscopy,
fluorescence
emission
time-dependent-density
functional
theory
(TD-DFT)
calculations.
inclusion
D-A
systems
and/or
π-extended
in
not
only
enables
adjustable
RGB
light
spectra
(300~700
nm)
but
also
yields
high
quantum
efficiencies
up
to
0.84
MeCN
solution.
Then,
with
ESIPT
(excited-state
intramolecular
proton
transfer)
property,
analysis
showed
that
probe
bis-Et-SA
bis-Ph-SA
could
recognize
Zn2+
via
“turn
on”
mode
During
detection
process,
demonstrate
rapid
response
selectivity
upon
addition
Zn2+.
coordination
oxygen
atom
nitrogen
a
tetrahedral
geometry
is
confirmed
Job’s
plot,
FT-IR,
1H
NMR
spectroscopy.
In
addition,
paper
test
Hela
cells
successfully
carried
out
detect
Moreover,
sensitivity
much
better
than
those
containing
one
chelating
unit
[O^N^N^O].
Язык: Английский