Recent advances in multicomponent synthesis of pyrazoles
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Pyrazole
moiety
is
considered
as
an
important
N-heterocycle
in
pharmaceuticals
and
many
other
functional
molecules.
The
utilization
of
multicomponent
reaction
a
major
tool
the
current
approaches
pyrazole
synthesis.
Considering
power
significance
synthesis,
we
review
herein
latest
developments
this
field.
According
to
typical
features,
contents
are
divided
into
reactions
with
different
NN
fragment
sources,
such
hydrazine,
hydrazone,
amidine,
nitrile,
diazo
compounds,
ring
construction,
covering
works
published
since
2019
date.
Язык: Английский
Electrochemical Annulation of p-Alkoxy or p-Hydroxy Anilines with Enaminones for Selective Indole and Benzofuran Synthesis
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 11, 2025
The
green
and
sustainable
electrochemical
oxidative
cyclization
of
enaminones
with
p-methoxy/p-hydroxy
anilines
has
been
developed,
enabling
the
regioselective
synthesis
indoles
benzofurans.
methods
are
significant
advantage
not
only
due
to
mild
metal-free
conditions,
but
also
because
employment
easily
available
stable
aniline
substrates
replace
unstable
quinoneimide
for
a
similar
annulation
in
previous
work.
Язык: Английский