Aptamer-enabled electrochemical bioplatform utilizing surface-modified g-C3N4/MoS2/PANI nanocomposite for detection of CA125 biomarker
Sensing and Bio-Sensing Research,
Год журнала:
2024,
Номер
45, С. 100669 - 100669
Опубликована: Июнь 28, 2024
Detecting
ovarian
cancer
at
an
early
stage
is
crucial
for
enhancing
patient
outcomes,
underscoring
the
demand
efficient
and
non-invasive
detection
method.
Cancer
antigen
125
(CA125)
a
vital
biomarker
in
detection,
there
pressing
to
develop
quick,
sensitive,
simple
Nanobiosensors
are
increasingly
being
used
by
scientists
due
their
high
selectivity
sensitivity,
allowing
swift
precise
of
wide
range
biomarkers.
This
study
aimed
design
fabricate
electrochemical
nanobiosensor
that
could
accurately
selectively
detect
CA125.
The
employed
graphitic
carbon
nitrides,
molybdenum
disulfide,
polyaniline
(g-C3N4/MoS2/PANI)
stabilize
aptamer
strands
on
modified
glassy
electrode.
aptasensor
was
perform
labeled
CA125,
utilizing
methylene
blue
label-free
ferrocyanide
methods.
Ferrocyanide
limits
were
determined
be
0.196
U.mL−1
blue,
with
linear
2–10
detection.
results
showed
electrode
exhibited
towards
CA125
superior
stability
compared
other
biomolecules.
also
displayed
impressive
performance
when
analyzing
serum
patients
healthy
people.
These
findings
hold
significant
promise
future
investigation
diagnosis.
novel
may
aid
management
cancer,
ultimately
leading
better
outcomes.
Язык: Английский
Cyclodextrin-based nanocarriers as promising scaffolds for overcoming challenges of doxorubicin delivery in cancer chemotherapy
Carbohydrate Polymer Technologies and Applications,
Год журнала:
2025,
Номер
unknown, С. 100677 - 100677
Опубликована: Янв. 1, 2025
Язык: Английский
A Density Functional Theory Study of the Physico-Chemical Properties of Alkali Metal Titanate Perovskites for Solar Cell Applications
Molecules,
Год журнала:
2024,
Номер
29(14), С. 3355 - 3355
Опубликована: Июль 17, 2024
The
urgent
need
to
shift
from
non-renewable
renewable
energy
sources
has
caused
widespread
interest
in
photovoltaic
technologies
that
allow
us
harness
readily
available
and
sustainable
solar
energy.
In
the
past
decade,
polymer
cells
(PSCs)
perovskite
(Per-SCs)
have
gained
attention
owing
their
low
price
easy
fabrication
process.
Charge
transport
layers
(CTLs),
transparent
conductive
electrodes
(TCEs),
metallic
top
are
important
constituents
of
PSCs
Per-SCs,
which
affect
efficiency
stability
these
cells.
Owing
disadvantages
current
materials,
including
instability
high
cost,
development
alternative
materials
attracted
significant
attention.
more
flexible
physical
chemical
characteristics,
ternary
oxides
considered
be
appealing
alternatives,
where
ATiO
Язык: Английский
Cyclodextrin nanocarriers in Coordination Chemistry: Enhancing encapsulation and targeted delivery of 5-Fluorouracil for cancer treatment
Results in Chemistry,
Год журнала:
2024,
Номер
12, С. 101878 - 101878
Опубликована: Окт. 30, 2024
Язык: Английский
Recent advancements in nanobiosensors for diagnosis of ovarian cancer: Analytical approaches
TrAC Trends in Analytical Chemistry,
Год журнала:
2024,
Номер
unknown, С. 118119 - 118119
Опубликована: Дек. 1, 2024
Язык: Английский
Recent Progress on Functional Electrospun Polymeric Nanofiber Membranes
Materials Today Communications,
Год журнала:
2024,
Номер
41, С. 110530 - 110530
Опубликована: Сен. 24, 2024
Язык: Английский
Preparation and Optimization of Electrospun Nylon‐6 Fiber‐Reinforced High Strength and Toughness Thermoplastic Polyurethane Composites for Potential Use in Prosthetic Heart Valves
Macromolecular Materials and Engineering,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 27, 2025
Abstract
The
interfacial
aspects
of
fiber
composites
are
widely
favored.
Here,
three
composite
strategies
based
on
hot‐pressing,
electrospinning,
and
impregnation
PA6
fibers
presented
for
the
preparation
fiber‐reinforced
thermoplastic
polyurethane
(PA6/TPU)
composites.
morphologies
electrospun
fiber/matrix
interface
mechanical
properties
PA6/TPU
investigated.
Under
optimal
conditions,
tensile
strength,
Young's
modulus,
toughness
H‐PA6/TPU
respectively
29.45
±
1.477
MPa,
47.28
2.61
38.03
1.996
MJ
m
−3
.
E‐PA6/TPU
28.03
1.411
73.81
4.16
24.12
1.265
,
respectively.
I‐PA6/TPU
elongation
at
break
is
≈240%.
Moreover,
without
loss
TPU
properties,
method
effectively
improves
adhesion
between
matrix,
significantly
improved
even
if
content
low.
simple
to
operate
can
be
extended
other
polymers
Язык: Английский
Optimizations of Electrospun Nylon Fibers Toward Potential Application in Artificial Heart Valve
Journal of Applied Polymer Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 28, 2025
ABSTRACT
Improving
the
mechanical
properties
of
novel
prosthetic
heart
valves
is
key
to
facilitating
application
biological
valves.
Screening
polymer
materials
that
can
be
used
for
basis
preparation
This
study
focused
on
screening
and
optimization
different
types
nylon
electrospun
fibers.
First,
nylon‐6
(PA
6),
nylon‐66
66),
nylon‐612
612),
nylon‐11
11),
nylon‐12
12)
were
selected
as
spinning
precursors,
only
PA
6,
66,
12
completely
dissolved
obtain
a
solution
with
concentration
16
wt%.
Among
them,
12,
66
fiber
membranes.
Then,
fibrous
membranes
obtained
under
conditions
19
kV,
distance
15–20
cm,
humidity
20%,
then
three
investigated
compared
each
other
fibers
nylon,
such
tensile
strength,
Young's
modulus,
toughness.
Finally,
we
chose
6
spinneret
designed
solutions
gradients,
subsequently
prepared
at
an
optimal
wt%
voltage
excellent
overall
performance:
diameter
was
concentrated
0.19
±
0.02
μm.
The
toughness
10.25
0.518
MPa,
101.12
5.85
2.51
0.145
MJ
m
−3
,
respectively.
promising
candidate
new
Язык: Английский
Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies
Results in Chemistry,
Год журнала:
2025,
Номер
unknown, С. 102298 - 102298
Опубликована: Апрель 1, 2025
Язык: Английский
A Polyurethane Electrospun Membrane Loaded with Bismuth Lipophilic Nanoparticles (BisBAL NPs): Proliferation, Bactericidal, and Antitumor Properties, and Effects on MRSA and Human Breast Cancer Cells
Journal of Functional Biomaterials,
Год журнала:
2024,
Номер
15(10), С. 309 - 309
Опубликована: Окт. 16, 2024
Electrospun
membranes
(EMs)
have
a
wide
range
of
applications,
including
use
as
local
delivery
systems.
In
this
study,
we
manufactured
polyurethane
Tecoflex™
EM
loaded
with
bismuth-based
lipophilic
nanoparticles
(Tecoflex™
EMs-BisBAL
NPs).
The
physicochemical
and
mechanical
characteristics,
along
the
antitumor
bactericidal
effects,
were
evaluated
using
breast
cancer
cell
line
methicillin-susceptible
resistant
Staphylococcus
aureus
(MRSA).
Drug-free
EMs
NPs
had
similar
fiber
diameters
4.65
±
1.42
µm
3.95
1.32
µm,
respectively.
did
not
negatively
impact
human
fibroblast
culture,
indicating
that
vehicle
is
biocompatible.
increased
94%
more
in
size
than
drug-free
EMs,
BisBAL
enhanced
hydration
capacity.
highly
against
both
S.
MRSA
clinical
isolates,
inhibiting
their
growth
by
93.11%
61.70%,
Additionally,
decreased
viability
MCF-7
tumor
cells
86%
after
24
h
exposure
70.1%
within
15
min.
Regarding
mechanism
action
NPs,
it
appears
to
disrupt
membrane.
conclusion,
constitute
an
innovative
low-cost
drug
system
for
postoperative
wound
infections.
Язык: Английский