Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis
Neuroscience & Biobehavioral Reviews,
Год журнала:
2024,
Номер
163, С. 105782 - 105782
Опубликована: Июнь 27, 2024
Cognitive
challenges
and
brain
structure
variations
are
common
in
autism
spectrum
disorder
(ASD)
but
rarely
explored
middle-to-old
aged
autistic
adults.
deficits
that
overlap
between
young
individuals
elderlies
with
dementia
raise
an
important
question:
does
compromised
cognitive
ability
during
early
development
drive
adults
to
be
more
vulnerable
pathological
aging
conditions,
or
it
protect
them
from
further
decline?
To
answer
this
question,
we
have
synthesized
current
theoretical
models
of
ASD
conducted
a
systematic
literature
review
(Jan
1,
1980
-
Feb
29,
2024)
meta-analysis
summarize
empirical
studies
on
deviations
We
findings
support
different
theories
addressed
study
limitations
future
directions.
This
sheds
light
the
poorly
understood
consequences
question
raised
by
community
pave
way
for
identify
sensitive
reliable
measures
best
predict
onset,
progression,
prognosis
ASD.
Язык: Английский
Self-Reported Psychological, Somatic, and Vasomotor Symptoms at Different Stages of the Menopause for Autistic and Non-autistic People
Journal of Women s Health,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
Background:
There
is
growing
awareness
that
the
experiences
of
neurodivergent
people
during
menopause
are
not
well
understood.
Menopause
may
be
particularly
challenging
for
autistic
due
to
common
co-occurring
conditions
such
as
depression
and
differences
in
sensory
processing.
The
few
(mostly
qualitative)
studies
explore
autism
suggest
traits
exacerbated.
Methods:
In
an
online
cross-sectional
survey,
we
examined
self-reported
symptoms
342
(autistic,
n
=
242
non-autistic,
100)
at
different
stages
their
reproductive
life
(premenopausal
[∼20%
sample],
menopausal
[∼30%],
postmenopausal
[∼50%]).
Results:
Autistic
reported
significantly
higher
rates
bothersome
psychological
somatic
than
non-autistic
people,
but
no
were
observed
vasomotor
symptoms.
Results
indicated
patterns
psychological,
somatic,
between
groups.
People
postmenopause
groups
negative
changes
symptoms,
women
these
more
women.
Whether
this
finding
related
observation
report
before
requires
further
investigation.
Conclusion:
This
analysis
suggests
experience
compared
with
people.
Longitudinal
examining
change
required
fully
understand
variables
impact
individual
Язык: Английский
Aging Well and Autism: A Narrative Review and Recommendations for Future Research
Healthcare,
Год журнала:
2024,
Номер
12(12), С. 1207 - 1207
Опубликована: Июнь 17, 2024
With
autism
first
recognized
in
the
1940s,
early
cohorts
of
autistic
children
are
beginning
to
enter
older
adulthood.
Little
is
known
about
experiences
and
outcomes
adults.
In
general
population,
"successful
aging"
a
dominant
model
among
gerontologists
used
evaluate
This
narrative
review
aims
provide
framework
for
understanding
supporting
successful
aging
Using
Fernández-Ballesteros'
four-domain
"aging
well"
we
knowledge
on
by
examining
health
functioning,
cognitive
physical
positive
affect
control,
social
participation
engagement.
Findings
indicate
that
adults
generally
poor,
marked
increased
medical
conditions,
low
adaptive
skills,
elevated
risk
decline,
limited
activity,
high
rates
mental
quality
life,
reduced
or
community
participation.
Patterns
challenges
similar
across
abilities
profiles
traits.
Challenges
next
steps
research
identified,
future
directions
field
discussed.
Язык: Английский