Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles DOI Creative Commons
Grace Neilsen,

Asha Maria Mathew,

J.M. Castro

и другие.

mBio, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

The coronavirus-induced disease 19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections, has had a devastating impact on millions of lives globally, with mortality rates and catastrophic social implications. Developing tools for effective vaccine strategies platforms is essential controlling preventing the recurrence such pandemics. Moreover, molecular virology that facilitate study viral pathogens, mutations, interactions various host proteins are essential. Viral replicon- virus-like particle (VLP)-based systems excellent examples tools. This review outlines importance, advantages, disadvantages both VLP-based have been developed SARS-CoV-2 helped scientific community in dimming intensity COVID-19 pandemic.

Язык: Английский

Staphylococcus Aureus-Related antibiotic resistance detection using synergy of Surface-Enhanced Raman spectroscopy and deep learning DOI
Zakarya Al‐Shaebi,

Fatma Uysal Ciloglu,

Mohammed Nasser

и другие.

Biomedical Signal Processing and Control, Год журнала: 2024, Номер 91, С. 105933 - 105933

Опубликована: Янв. 10, 2024

Язык: Английский

Процитировано

12

Innovative and versatile surface-enhanced Raman spectroscopy-inspired approaches for viral detection leading to clinical applications: A review DOI

Jaya Sitjar,

Jiunn‐Der Liao, Han Lee

и другие.

Analytica Chimica Acta, Год журнала: 2024, Номер 1325, С. 342917 - 342917

Опубликована: Июнь 27, 2024

Язык: Английский

Процитировано

3

Fast screening of COVID-19 inpatient samples by integrating machine learning and label-free SERS methods DOI

Jaya Sitjar,

Huey‐Pin Tsai, Han Lee

и другие.

Analytica Chimica Acta, Год журнала: 2025, Номер 1350, С. 343872 - 343872

Опубликована: Фев. 25, 2025

Язык: Английский

Процитировано

0

Single-shot, Receptor-Free, Rapid Detection and Classification of Five Respiratory Viruses by Machine learning Integrated SERS Sensing Platform DOI
Arti Yadav,

Rakesh Naik,

Ekta Gupta

и другие.

Biosensors and Bioelectronics, Год журнала: 2025, Номер unknown, С. 117394 - 117394

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Limit of Detection of Raman Spectroscopy Using Polystyrene Particles from 25 to 1000 nm in Aqueous Suspensions DOI Creative Commons
Cindy Mayorga, Shreya Milind Athalye,

Miad Boodaghidizaji

и другие.

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Raman spectroscopy is an analytical method capable of detecting various microorganisms and small particles. Here, we used 25-1000 nm polystyrene particles in aqueous suspensions, which are comparable size to viral aggregates, determine the limit detection (LOD) a confocal microscope. We collected spectra using 785 wavelength laser with power 300 mW 10 s exposure time 5× objective lens. detected most prominent peak at 1001 cm-1, corresponding ring breathing mode. established minimum maximum LOD (LODmin LODmax) Kernel partial least-squares model. The smallest 50 was identified as 1.80 × 1012-8.31 1012 particle/mL, for largest 1000 nm, 5.11 108-2.53 109 particle/mL. demonstrated that nondestructive under these conditions by comparing particle before after collecting dynamic light scattering. Due their similarity this systematic characterization provides detailed information on spectral signatures suspensions. These findings establish foundation suspensions highlight its potential tool real-time monitoring vaccine manufacturing.

Язык: Английский

Процитировано

0

Development of silver-based hybrid nanoparticles loaded with eEF2 K-siRNA and quercetin against triple-negative breast cancer DOI Creative Commons

Orhan Burak Eksi,

Ahsen Güler, Münevver Akdeniz

и другие.

Drug Delivery and Translational Research, Год журнала: 2025, Номер unknown

Опубликована: Апрель 23, 2025

Язык: Английский

Процитировано

0

Nanodelivery in Gene Therapy DOI

Orhan Burak Eksi,

Aybuke Ulku Kutlu,

Kübra Yumuk

и другие.

Springer eBooks, Год журнала: 2024, Номер unknown, С. 1 - 40

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

1

非相干拉曼显微技术及其生物医学应用(特邀) DOI Open Access

黎钰怡 Li Yuyi,

干越 Gan Yue,

牛犇 Niu Ben

и другие.

Laser & Optoelectronics Progress, Год журнала: 2024, Номер 61(6), С. 0618009 - 0618009

Опубликована: Янв. 1, 2024

拉曼技术具有非侵入、分子指纹、不受水干扰、制样简单、光谱分辨率高等优点,在很多领域都是一种广受欢迎的研究工具。尤其在生物医学领域,拉曼技术不仅可以本征地捕捉正常生理或病理所携带的不同化学信息,而且该技术适用于检测各种常见的生物和临床样品(包括细胞、组织、体液和微生物等),目前很多课题组的研究结果都表明拉曼技术在生物医学领域具有巨大的应用前景。本文首先介绍自发拉曼散射和表面增强拉曼散射的基本工作机理,接着介绍分析处理拉曼数据(光谱和图像)的步骤和算法,然后简单总结了近年来非相干拉曼显微技术在生物医学上的研究成果,最后指出拉曼技术目前面临的挑战并展望了其未来可能的发展方向。

Процитировано

1

Mammalian cells-based platforms for the generation of SARS-CoV-2 virus-like particles DOI

Ghada Elfayres,

Ricky Raj Paswan,

Laura Sika

и другие.

Journal of Virological Methods, Год журнала: 2023, Номер 322, С. 114835 - 114835

Опубликована: Окт. 21, 2023

Язык: Английский

Процитировано

3

Focused ion beam-fabricated nanorod substrate for label-free surface-enhanced Raman spectroscopy and enabling dual virus detection DOI
Han Lee,

Jiunn-Der Liao,

Huey‐Pin Tsai

и другие.

Talanta, Год журнала: 2024, Номер 278, С. 126466 - 126466

Опубликована: Июнь 22, 2024

Язык: Английский

Процитировано

0