GC/MS and LC Composition Analysis of Essential Oil and Extracts From Wild Rosemary: Evaluation of Their Antioxidant, Antimicrobial, and Anti‐Inflammatory Activities DOI

Nasma Mahboub,

Inasse Cherfi,

Salah Eddine Laouini

и другие.

Biomedical Chromatography, Год журнала: 2025, Номер 39(5)

Опубликована: Апрель 10, 2025

ABSTRACT Rosmarinus officinalis L. (rosemary) is a widely used medicinal plant known for its antioxidant, antimicrobial, and anti‐inflammatory properties. This study evaluates the bioactive potential of essential oil (EO), methanolic (ME), aqueous (AE) extracts. GC‐MS analysis identified α‐pinene (21.37%), bornanone (12.73%), eucalyptol (8.28%) as major EO components, while HPLC revealed ME's richness in salicylic acid (5.11 μg/mg) rutin (0.43 μg/mg). Antioxidant activity, assessed via DPPH FRAP assays, showed ME with strongest radical scavenging capacity (IC 50 = 27.30 ± 2.4%) reducing power 90.88 6.7%). Antimicrobial testing most effective, particularly against Staphylococcus aureus (33 mm inhibition zone) Bacillus subtilis (32 mm), AE exhibited moderate activity. Pseudomonas aeruginosa was resistant to all Additionally, demonstrated notable activity 55.88 1.02%). These findings highlight rosemary rich source compounds strong pharmacological potential, positioning best potent an effective agent.

Язык: Английский

GC/MS and LC Composition Analysis of Essential Oil and Extracts From Wild Rosemary: Evaluation of Their Antioxidant, Antimicrobial, and Anti‐Inflammatory Activities DOI

Nasma Mahboub,

Inasse Cherfi,

Salah Eddine Laouini

и другие.

Biomedical Chromatography, Год журнала: 2025, Номер 39(5)

Опубликована: Апрель 10, 2025

ABSTRACT Rosmarinus officinalis L. (rosemary) is a widely used medicinal plant known for its antioxidant, antimicrobial, and anti‐inflammatory properties. This study evaluates the bioactive potential of essential oil (EO), methanolic (ME), aqueous (AE) extracts. GC‐MS analysis identified α‐pinene (21.37%), bornanone (12.73%), eucalyptol (8.28%) as major EO components, while HPLC revealed ME's richness in salicylic acid (5.11 μg/mg) rutin (0.43 μg/mg). Antioxidant activity, assessed via DPPH FRAP assays, showed ME with strongest radical scavenging capacity (IC 50 = 27.30 ± 2.4%) reducing power 90.88 6.7%). Antimicrobial testing most effective, particularly against Staphylococcus aureus (33 mm inhibition zone) Bacillus subtilis (32 mm), AE exhibited moderate activity. Pseudomonas aeruginosa was resistant to all Additionally, demonstrated notable activity 55.88 1.02%). These findings highlight rosemary rich source compounds strong pharmacological potential, positioning best potent an effective agent.

Язык: Английский

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