The Clinical Impact of Real-Time fMRI Neurofeedback on Emotion Regulation: A Systematic Review

Brain Sciences, Год журнала: 2024, Номер 14(7), С. 700 - 700

Опубликована: Июль 12, 2024

Emotion dysregulation has long been considered a key symptom in multiple psychiatric disorders. Difficulties emotion regulation have associated with neural fronto-limbic circuits. Real-time fMRI-based neurofeedback (rt-fMRI-NFB) become increasingly popular as potential treatment for emotional disorders, it is able to directly target the impaired However, clinical impact of these rt-fMRI-NFB protocols populations still largely unknown. Here we provide comprehensive overview primary studies from 2010 2023 that used regulation. We assessed 41 out 4001 original methodological quality and risk bias synthesised concerning frequency significant rt-fMRI-NFB-related effects on behaviour level. Successful modulation brain activity was reported between 25 50 percent study samples, while samples were more diverse than healthy samples. Interestingly, behavioural improvement over 75 showed improvements 0 percent. Concerning subsamples, observed up 100 major depressive disorder (MDD) post-traumatic stress (PTSD) Substance use benefits ranging Neural appeared be less frequent improvements: most outcomes ranged MDD substance PTSD. Using individualised regions interest (ROIs) training resulted solely based amygdala or prefrontal cortex. While studies, heterogeneous, which limits current evaluation putative dysregulation.

Язык: Английский

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Une revue narrative sur l’insula : Gardienne de la relation corps-cerveau ?

Cortica, Год журнала: 2024, Номер 3(1), С. 413 - 460

Опубликована: Март 20, 2024

Cet article propose une revue narrative exhaustive sur l'insula, région cérébrale complexe et stratégiquement située, son rôle central dans les interactions corps-cerveau-comportement. Il souligne l'importance de l'insula la perception interne (intéroception), le traitement émotionnel cognitif, ainsi que diverses fonctions neuropsychologiques. L'article évoque l'histoire découverte sa structure unique, ses connexions tentaculaires avec d'autres régions cérébrales, implication des sensorimotrices, émotionnelles, sociales, cognitives. aborde également régulation émotionnelle, mettant en lumière interaction cortex préfrontal ventromédian temporo-pariétal. La se concentre l'impact divers troubles psychiques tels dépression, alimentaires, syndrome stress post-traumatique, du spectre autistique, suggérant dysfonctionnements peuvent être un dénominateur commun à plusieurs pathologies mentales. Des approches thérapeutiques innovantes, telles méditation pleine conscience neurofeedback par IRMf, sont discutées comme moyens potentiels d'améliorer fonctionnalité traiter associés. cruciale poursuivre recherche pour mieux comprendre santé mentale physique, développer stratégies ciblées. En résumé, cette offre perspective complète évidence pivot l'intégration processus corporels, émotionnels cognitifs, potentiel tant cible thérapeutique psychiques.

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Intra- and Inter-Network Connectivity of the Default Mode Network Differentiating Treatment-Resistant Depression from Treatment-Sensitive Depression

Опубликована: Янв. 1, 2024

Understanding why some patients with depression remain resistant to antidepressant medication could be elucidated by investigating their associated neural features. Although research has consistently demonstrated abnormalities in the anterior cingulate cortex (ACC) – a region that is part of default mode network (DMN) - treatment-resistant (TRD), considerable gap exists discerning how these networks distinguish TRD from treatment-sensitive (TSD). In this context, we aimed evaluate resting-state functional connectivity (rsFC) ACC other regions DMN better understand role structure pathophysiology TRD. 35 patients, TSD and 38 healthy controls (HC) underwent MRI protocol. Seed-based analyses were performed, comparing three groups for between two subregions (the subgenual (sgACC) rostral (rACC)) (p<0.05 FWE corrected). Furthermore, inter-network was explored independent component (ICA) (p<0.01, FDR The results hyperconnectivity rACC posterior relative HC (F(2,105)=5.335, p<0.05). ICA also found lower default-mode somatomotor, cognitive control, salience limbic system group compared HC. These differentiate TSD, providing confirmatory evidence preliminary its interactions as key mechanisms underlying treatment non-responsiveness.

Язык: Английский

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Intra- and Inter-Network connectivity of the default mode network differentiates Treatment-Resistant depression from Treatment-Sensitive depression

NeuroImage Clinical, Год журнала: 2024, Номер 43, С. 103656 - 103656

Опубликована: Янв. 1, 2024

Understanding why some patients with depression remain resistant to antidepressant medication could be elucidated by investigating their associated neural features. Although research has consistently demonstrated abnormalities in the anterior cingulate cortex (ACC) - a region that is part of default mode network (DMN) treatment-resistant (TRD), considerable gap exists discerning how these networks distinguish TRD from treatment-sensitive (TSD). We aimed evaluate resting-state functional connectivity (rsFC) ACC other regions DMN better understand role this structure pathophysiology TRD. 35 patients, TSD and 38 healthy controls (HC) underwent MRI protocol. Seed-based analyses were performed, comparing three groups for between two subregions (the subgenual (sgACC) rostral (rACC)) (p < 0.05 FWE corrected). Furthermore, inter-network was explored independent component (ICA) 0.01, FDR The results hyperconnectivity rACC posterior relative HC (F(2,105) = 5.335, p 0.05). ICA found visual (TRDTSD), differentiating clinical groups. These provide confirmatory evidence preliminary its interactions as key mechanisms underlying treatment non-responsiveness.

Язык: Английский

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Modulation of High‐Frequency rTMS on Reward Circuitry in Individuals with Nicotine Dependence: A Preliminary fMRI Study

Neural Plasticity, Год журнала: 2024, Номер 2024(1)

Опубликована: Янв. 1, 2024

Although previous studies have shown that repetitive transcranial magnetic stimulation (rTMS) can ameliorate addictive behaviors and cravings, the underlying neural mechanisms remain unclear. This study aimed to investigate effect of high‐frequency rTMS with left dorsolateral prefrontal cortex (L‐DLPFC) as a target region on smoking addiction in nicotine‐dependent individuals by detecting change spontaneous brain activity reward circuitry. We recruited 17 nicotine‐dependence participants, who completed 10 sessions Hz over 2‐week period underwent evaluation several dependence‐related scales, resting‐state fMRI scan before after treatment. Functional connectivity (FC) analysis was conducted reward‐related regions seeds, including ventral tegmental area, bilateral nucleus accumbens (NAc), DLPFC, amygdala. found that, treatment, showed reduced nicotine dependence, alleviated tobacco withdrawal symptoms, diminished cravings. The right NAc increased FC fusiform gyrus, inferior temporal gyrus (ITG), calcarine fissure surrounding cortex, superior occipital (SOG), lingual cuneus. No significant changes were observed other seed regions. Moreover, between ITG well SOG negatively correlated scale scores. Our findings suggest L‐DLPFC‐rTMS reduces dependence improves dysfunctional circuitry may be mechanism for its therapeutic target.

Язык: Английский

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A network analysis of eating disorder, PTSD, major depression, state‐trait anxiety, and quality of life measures in eating disorder patients treated in residential care

European Eating Disorders Review, Год журнала: 2024, Номер unknown

Опубликована: Сен. 17, 2024

Abstract Background The network approach in the eating disorder (ED) field has confirmed important links between EDs and posttraumatic stress (PTSD) symptoms. However, studies including comorbid symptoms are scarce, which limits our understanding of potentially connections. We hypothesised that anxiety, depression poor quality life (QOL) would provide a more complete picture central, maintaining factors. Methods Network analysis using R was performed 2178 adult ED patients (91% female) admitted to residential treatment. Assessments included Examination Questionnaire (EDEQ), Eating Disorders Inventory (EDI‐2), PTSD Checklist for DSM‐5 (PTSD clusters (PCL‐5)), Patient Health (PHQ‐9), Spielberger State‐Trait Anxiety Scale (STAI), QOL (EDQOL), measure EDs, PTSD, major depression, state‐trait QOL, respectively. Results EDI‐2 ineffectiveness showed highest centrality (expected influence) followed by interoceptive awareness, STAI state EDEQ shape concern, EDQOL psychological subscale, cluster D (hyperarousal) Disorder Quality Life physical‐cognitive subscales PHQ‐9 depressive, anxiety PCL‐5 E (negative alterations mood cognition) bridge expected influence, suggesting their interactive role ED‐PTSD comorbidity. Conclusions This is first interaction include measures large clinical sample patients. Our results indicate several symptom likely maintain comorbidity may be targets integrated

Язык: Английский

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Exploring the impact of biological sex on intrinsic connectivity networks in PTSD: A data-driven approach

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Год журнала: 2024, Номер 136, С. 111180 - 111180

Опубликована: Окт. 22, 2024

Язык: Английский

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Genetic Vulnerability to Social Anxiety Disorder

Current topics in behavioral neurosciences, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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Meta-analytic connectivity perturbation analysis (MACPA): a new method for enhanced precision in fMRI connectivity analysis

Brain Structure and Function, Год журнала: 2024, Номер 230(1)

Опубликована: Дек. 24, 2024

Язык: Английский

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Eplerian Life Philosophy: Thinking and Feelings from Five Locations

Open Journal of Philosophy, Год журнала: 2023, Номер 13(02), С. 336 - 341

Опубликована: Янв. 1, 2023

The Eplerian Life Philosophy is “know who you are moment by moment” which means knowing where you’re thinking from, and that are. There five locations to think feel from including the head, heart, gut, body, mind. Limit head anger stress centers less than ten seconds. Feel heart with kindness yourself others. Be in mind solve problems help for people want improve their lives being true authentic self living best at home, work, community.

Язык: Английский

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