Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects
Critical Reviews in Biotechnology,
Год журнала:
2025,
Номер
unknown, С. 1 - 19
Опубликована: Янв. 6, 2025
This
comprehensive
review
aims
to
explore
and
consolidate
the
current
knowledge
on
dendrobine,
including
its
biological
activities,
molecular
mechanisms
of
action,
effects
various
physiological
processes,
potential
toxicity,
safety
considerations,
in
order
unlock
full
applications.
Dendrobine
has
diverse
effects,
anti-inflammatory,
antioxidant,
neuroprotective,
immunomodulatory,
anticancer
effects.
also
exerts
neuroprotective
by
boosting
neuronal
survival,
reducing
neuroinflammation,
regulating
neurotransmitter
release.
immunomodulatory
that
control
immune
cell
function
modify
immunological
responses.
exhibits
properties
decreasing
tumor
angiogenesis
metastasis,
causing
apoptosis
cancer
cells,
inhibiting
growth.
discusses
idea
a
circular
economy
produce
researching
cutting-edge
sustainable
methods
maximize
resource
efficiency
reduce
environmental
Additionally,
supporting
principles
for
production
outlining
future
study
areas,
this
discovery
will
help
use
dendrobine
variety
applications
while
preserving
environment.
Future
research
should
focus
advancing
application
personalized
medicine,
exploring
green
bioproduction
methods,
ensuring
ethical
sourcing
practices.
An
enhanced
understanding
synergistic
therapies
could
revolutionize
healthcare,
whereas
conservation
efforts
safeguard
ecological
impact.
Язык: Английский
Erianin isolated from Dendrobium huoshanense alleviated neuroinflammation in MPTP-induced Parkinson's disease model via NF-κB/NLRP3 pathway
Journal of Ethnopharmacology,
Год журнала:
2025,
Номер
unknown, С. 119620 - 119620
Опубликована: Март 1, 2025
Язык: Английский
Neuroprotective effects of dendrobium endophytes metabolites in SH-SY5Y cells via the Nrf2/Keap1 pathway
Heliyon,
Год журнала:
2024,
Номер
10(6), С. e28222 - e28222
Опубликована: Март 1, 2024
Recent
studies
have
revealed
that
endophytes
in
plants
can
produce
metabolites
with
activity
is
comparable
to
or
identical
the
host.
Dendrobine
has
attracted
much
attention
field
of
neurodegenerative
diseases
by
exhibiting
anti-oxidative
stress
and
neuroprotective
effects.
This
study
aimed
investigate
protective
effects
mechanisms
dendrobium
Pseudomonas
protegens
CM-YJ44
Priestia
megaterium
D-HT207
against
H2O2-induced
oxidative
injury
SH-SY5Y
cells.
Results
showed
there
were
50
compounds
72
D-HT207.
Those
both
increased
significantly
cell
viability,
decreased
contents
ROS
It
was
confirmed
inhibited
cells,
which
mechanism
related
inhibition
production,
alteration
MMP,
apoptosis
inflammatory
factors
expression
via
Nrf2/Keap1
pathway.
Язык: Английский