Therapeutic potential of flavonoids in gastrointestinal cancer: Focus on signaling pathways and improvement strategies (Review)
Molecular Medicine Reports,
Год журнала:
2025,
Номер
31(4), С. 1 - 34
Опубликована: Фев. 24, 2025
Flavonoids
are
a
group
of
polyphenolic
compounds
distributed
in
vegetables,
fruits
and
other
plants,
which
have
considerable
antioxidant,
anti‑tumor
anti‑inflammatory
activities.
Several
types
gastrointestinal
(GI)
cancer
the
most
common
malignant
tumors
world.
A
large
number
studies
shown
that
flavonoids
inhibitory
effects
on
cancer,
they
recognized
as
class
potential
drugs.
Therefore,
present
review
investigated
molecular
mechanisms
treatment
different
GI
summarized
drug
delivery
systems
commonly
used
to
improve
their
bioavailability.
First,
classification
therapeutic
various
human
diseases
were
briefly
introduced.
Then,
clarify
mechanism
action
body,
metabolic
process
body
associated
signaling
pathways
causing
five
discussed,
well
corresponding
targets
flavonoids.
Finally,
clinical
settings,
poor
water
solubility,
low
permeability
inferior
stability,
lead
absorption
efficiency
vivo.
three
widely
summarized.
Suggestions
for
improving
bioavailability
focus
next
stage
research
also
put
forward.
Язык: Английский
Therapeutic potential and limitation of condensed and hydrolyzed tannins in Parkinson's disease
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 141814 - 141814
Опубликована: Март 1, 2025
Язык: Английский
Comparative analysis of phytochemical and antioxidant potential in traditional medicinal plants: Insights from solvent-based extractions
Food Bioscience,
Год журнала:
2025,
Номер
unknown, С. 106603 - 106603
Опубликована: Апрель 1, 2025
Язык: Английский
Assessing the therapeutic potential of quercetin, a widely spread flavonoid, in the prevention and management of chronic and degenerative diseases through a modern Chinese medicine perspective
Pharmacological Research - Modern Chinese Medicine,
Год журнала:
2025,
Номер
15, С. 100630 - 100630
Опубликована: Май 29, 2025
Язык: Английский